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Peptide-driven approaches in advanced wound healing materials

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收录情况： ◇ SCIE

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机构： [1]Department of General Surgery, Wusheng County People's Hospital (Wusheng Hospital Affiliated Hospital of North Sichuan Medical College), Guangan 638400, China. [2]Preventive Medicine, Shandong Academy of Occupational Health and Occupational Medicine, Occupational Disease Hospital of Shandong First Medical University (Shandong Province Hospital Occupational Disease Hospital), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, Shandong, China. [3]Department of Pharmacology and NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore. [4]Department of Urology, Kidney and Urology Center, Pelvic Floor Disorders Center, Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518107, China. [5]Department of Radiation Oncology, Precision Radiation in Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan 610041, China.

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关键词： peptide-based materials wound healing antimicrobial peptides tissue regeneration bioactive hydrogels

摘要：

Peptide-based materials, such as antimicrobial peptides (AMPs), cell-penetrating peptides (CPPs), angiogenic peptides, and extracellular matrix (ECM)-mimetic peptides, offer unique multifunctional benefits for wound healing, including infection control, enhanced angiogenesis, immunomodulation, and tissue regeneration. Representative platforms, including hydrogels, nanofibers, functionalized dressings, and delivery systems, leverage these peptides for sustained therapeutic action and improved healing. Despite these promising advances, significant translational barriers remain, including peptide stability, enzymatic degradation, manufacturing scalability, and regulatory approval. Addressing these barriers through optimized peptide engineering and delivery strategies is essential for the clinical translation and wider clinical adoption of peptide-driven wound therapies.Copyright © 2025 Elsevier Ltd. All rights reserved.

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出版当年[2025]版中科院分区表Review为是的期刊

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大类 | 2 区医学

小类 | 2 区药学

最新[2025]版

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大类 | 2 区医学

小类 | 2 区药学

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出版当年[2024]版：

Q1 PHARMACOLOGY & PHARMACY

最新[2024]版：

Q1 PHARMACOLOGY & PHARMACY

影响因子： 7.5 最新[2024版] 8.1 最新五年平均 7.5 出版当年[2024版] 0 出版当年五年平均 7.5 出版前一年[2024版]

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第一作者机构： [1]Department of General Surgery, Wusheng County People's Hospital (Wusheng Hospital Affiliated Hospital of North Sichuan Medical College), Guangan 638400, China.

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