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Radiotherapy combined icaritin promote cytotoxic T cell infiltration in tumor microenvironment

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收录情况: ◇ SCIE ◇ CPCI(ISTP)

机构: [1]Chengdu Univ Tradit Chinese Med, Sch Basic Med Sci, Chengdu, Peoples R China [2]Univ Elect Sci & Technol China, Sch Med, Chengdu, Peoples R China [3]Univ Elect Sci & Technol China, Affiliated Canc Hosp, Sichuan Clin Res Ctr Canc, Sichuan Canc Ctr,Basic Res Ctr,Sichuan Canc Hosp, Chengdu, Peoples R China [4]Univ Elect Sci & Technol China, Affiliated Canc Hosp, Sichuan Canc Hosp & Inst,Radiat Oncol Key Lab Sic, Sichuan Canc Ctr,Dept Radiat Oncol,Sichuan Clin R, Chengdu, Peoples R China
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关键词: tumor microenvironment cytotoxic T cell

摘要:
Radiotherapy played pivotal roles in curing cancer itself as well as shaping tumor immune microenvironment. Recent studies have been focused on combined strategies to magnify tumor control with local radiotherapy. Icaritin is a prenylflavonoid derivative from plants of the Epimedium genus, recently been implicated as a novel immune-modulator in cancer treatment. Here we investigated the anti-tumor potential of icaritin combined radiotherapy and its immune mechanisms.

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最新[2023]版:
大类 | 1 区 医学
小类 | 2 区 肿瘤学 2 区 核医学
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出版当年[2024]版:
最新[2023]版:
Q1 ONCOLOGY Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2023版]

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第一作者机构: [1]Chengdu Univ Tradit Chinese Med, Sch Basic Med Sci, Chengdu, Peoples R China
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