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Bacterial Proteins and Peptides as Potential Anticancer Agents: A Novel Search for Protein-based Therapeutics

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资源类型：
Pubmed体系：
作者：
Mahitha Pyla[1] * ; Sanjana Kankipati[1] * ; B. Sumithra[1,*2] ; Piyush Kumar Mishra[2] ; Bishwambhar Mishra[1] ; Sanjeeb Kumar Mandal[1] ; Jibanjyoti Panda[3] ; Hitesh Chopra[4] ; Avula Satya Kumar[5] ; Mohamed S. Attia[6] ; Yugal Kishore Mohanta[3] ; Mohammad Amjad Kamal[7,8,9,10,*1] ;
机构： [1]Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad -500075, Telangana, India [2]Department of Botany, B. N. College, Dhubri-783324, Assam, India [3]Nanobiotechnology and Translational Knowledge Laboratory, Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Techno City, 9th Mile, Baridua--793101, Ri-Bhoi, Meghalaya, India [4]Department of Biosciences, Saveetha School of Engineering,Saveetha Institute of Medical and Technical Sciences, Chennai-602105, Tamil Nadu, India [5]Natural andMedical Sciences Research Centre, University of Nizwa, Nizwa, 616, Oman [6]Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig44519, Egypt [7]Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, China [8]King Fahd Medical Research Center, King Abdulaziz University, Saudi Arabia [9]Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Bangladesh [10]Enzymoics, 7Peterlee place, Hebersham, NSW 2770,Novel Global Community Educational Foundation, Australia
出处：
DOI： 10.2174/0109298673253414231127162817
ISSN：

关键词： Cancer anti-cancer drugs bacterial peptides anti-cancer antibiotics anti-cancer enzymes bacteriocins bacterial toxins ribosomal peptides

摘要：
Tumor diseases remain among the world's primary causes of death despite substantial advances in cancer diagnosis and treatment. The adverse chemotherapy problems and sensitivity towards drugs for some cancer types are among the most promising challenges in modern treatment. Finding new anti-cancer agents and drugs is, therefore, essential. A significant class of biologically active substances and prospective medications against cancer is comprised of bacterial proteins and peptides. Among these bacterial peptides, some of them, such as anti-cancer antibiotics and many toxins like diphtheria are widely being used in the treatment of cancer. In contrast, the remaining bacterial peptides are either in clinical trials or under research in vitro studies. This study includes the most recent information on the characteristics and mechanism of action of the bacterial peptides that have anti-cancer activities, some of which are now being employed in cancer therapy while some are still undergoing research.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

基金：
This study is supported by the SERB-DST, Government of India, through a research grant provided to Nano-biotechnology and Translational Knowledge Laboratory (Grant No. SRG/2022/000641).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2024]版：
无
最新[2023]版：
大类 | 4 区 医学
小类 | 3 区 生化与分子生物学 3 区 药物化学 3 区 药学
第一作者：
第一作者机构： [1]Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad -500075, Telangana, India
共同第一作者：
通讯作者：
通讯机构： [1]Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad -500075, Telangana, India [7]Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, China [8]King Fahd Medical Research Center, King Abdulaziz University, Saudi Arabia [9]Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Bangladesh [10]Enzymoics, 7Peterlee place, Hebersham, NSW 2770,Novel Global Community Educational Foundation, Australia [*1]Enzymoics, 7Peterlee place, Hebersham, NSW 2770,Novel Global Community Educational Foundation, Australia [*2]Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad - 500075, Telangana, India
推荐引用方式(GB/T 7714)：
Mahitha Pyla,Sanjana Kankipati,B. Sumithra,et al.Bacterial Proteins and Peptides as Potential Anticancer Agents: A Novel Search for Protein-based Therapeutics[J].Current Medicinal Chemistry.2024,doi:10.2174/0109298673253414231127162817.
APA：
Mahitha Pyla,Sanjana Kankipati,B. Sumithra,Piyush Kumar Mishra,Bishwambhar Mishra...&Mohammad Amjad Kamal.(2024).Bacterial Proteins and Peptides as Potential Anticancer Agents: A Novel Search for Protein-based Therapeutics.Current Medicinal Chemistry,,
MLA：
Mahitha Pyla,et al."Bacterial Proteins and Peptides as Potential Anticancer Agents: A Novel Search for Protein-based Therapeutics".Current Medicinal Chemistry .(2024)

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