高级检索
当前位置: 首页 > 详情页

Use of albumin infusion for cirrhosis-related complications: An international position statement

文献详情

资源类型:
Pubmed体系:
机构: [1]Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China [2]Department of Life Sciences and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China [3]Liver Research Unit, Medica Sur Clinic and Foundation, National Autonomous University of Mexico, Mexico City, Mexico [4]Internal Medicine Department, Botucatu Medical School, São Paulo, Brazil [5]Medicina Interna 1, Azienda di Rilievo Nazionale ad Alta Specializzazione Civico-Di Cristina-Benfratelli, Palermo, Italy [6]Clinical and Translational Hepatology, The Liver Institute, Center of Excellence in GI Sciences, Rajagiri Hospital, Aluva, India [7]Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany [8]Division of Gastroenterology, Department of Internal Medicine, Bezmialem Vakif University, Istanbul, Turkey [9]Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy [10]Department of Gastroenterology and Hepatology, Theodor Bilharz Research Institute, Cairo, Egypt [11]Department of Gastroenterology and Hepatology, Changi General Hospital, Singapore [12]Serviço de Cuidados Intensivos, Unidade de Cuidados Intermédios Médico-Cirúrgica, Centro Hospitalar Universitário do Porto, Porto, Portugal [13]Department of Internal Medicine II, Division of Gastroenterology and Hepatology, Klinikum Hanau, Germany [14]Serviço de Gastrenterologia e Hepatologia, Hospital de Santa Maria-Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal [15]Sección Hepatología, Hospital Dr. Carlos B. Udaondo. Ciudad Autónoma de Buenos Aires, Argentina [16]Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand [17]Centre Hospitalier Universitaire de Besançon, Hôpital Jean Minjoz, Service d’Hépatologie et de Soins Intensifs Digestifs, Besançon, France [18]Kalinga Gastroenterology Foundation, Odisha, India [19]Section of Gastroenterology, Boston Medical Center, Boston, MA, USA [20]Department of Internal Medicine, Division of Hepatology, Sandra Atlas Bass Center for Liver Diseases & Transplantation, Donald and Barbara Zucker School of Medicine for Hofstra/Northwell Health, Manhasset, New York, USA [21]Department of Translational and Precision Medicine, “Sapienza” University of Rome, Rome, Italy [22]Department of Gastroenterology, Juntendo University, Hongo, Bunkyo-ku, Tokyo, Japan [23]First Department of Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece [24]Division of General Surgery and Liver Transplantation, San Camillo Hospital, Rome, Italy [25]Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China [26]Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India [27]Senior Department of Hepatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China [28]Department of Gastroenterology, University of Modena & Reggio Emilia and Azienda Ospedaliero-Universitaria di Modena, Italy [29]Institute of Clinical Research, University of Southern Denmark, Odense, Denmark [30]Department of Medicine, University of Toronto, Toronto, ON, Canada [31]Liver Failure Group, UCL Institute for Liver and Digestive Health, The Royal Free Hospital, University College London, London, UK [32]Division of Medicine, Royal Free Campus, London, UK [33]Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
出处:

关键词: Decompensated Human albumin Kidney injury Liver failure Management Portal hypertension Sepsis

摘要:
Numerous studies have evaluated the role of human albumin (HA) in managing various liver cirrhosis-related complications. However, their conclusions remain partially controversial, probably because HA was evaluated in different settings, including indications, patient characteristics, and dosage and duration of therapy.Thirty-three investigators from 19 countries with expertise in the management of liver cirrhosis-related complications were invited to organise an International Special Interest Group. A three-round Delphi consensus process was conducted to complete the international position statement on the use of HA for treatment of liver cirrhosis-related complications.Twelve clinically significant position statements were proposed. Short-term infusion of HA should be recommended for the management of hepatorenal syndrome, large volume paracentesis, and spontaneous bacterial peritonitis in liver cirrhosis. Its effects on the prevention or treatment of other liver cirrhosis-related complications should be further elucidated. Long-term HA administration can be considered in specific settings. Pulmonary oedema should be closely monitored as a potential adverse effect in cirrhotic patients receiving HA infusion.Based on the currently available evidence, the international position statement suggests the potential benefits of HA for the management of multiple liver cirrhosis-related complications and summarises its safety profile. However, its optimal timing and infusion strategy remain to be further elucidated.Thirty-three investigators from 19 countries proposed 12 position statements on the use of human albumin (HA) infusion in liver cirrhosis-related complications. Based on current evidence, short-term HA infusion should be recommended for the management of HRS, LVP, and SBP; whereas, long-term HA administration can be considered in the setting where budget and logistical issues can be resolved. However, pulmonary oedema should be closely monitored in cirrhotic patients who receive HA infusion.© 2023 The Author(s).

基金:
语种:
PubmedID:
中科院(CAS)分区:
出版当年[2023]版:
大类 | 1 区 医学
小类 | 2 区 胃肠肝病学
最新[2023]版:
大类 | 1 区 医学
小类 | 2 区 胃肠肝病学
第一作者:
第一作者机构: [1]Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China [2]Department of Life Sciences and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China
通讯作者:
通讯机构: [1]Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China [2]Department of Life Sciences and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China [33]Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy [*1]Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Northern Theater Command, 83 Wenhua Road, Shenyang, Liaoning Province, 110840, China [*2]Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, Bologna, 40138, Italy
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:46895 今日访问量:0 总访问量:3333 更新日期:2024-11-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 四川省肿瘤医院 技术支持:重庆聚合科技有限公司 地址:成都市人民南路四段55号