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The Role of Mesenchymal Stem Cells in Cancer Immunotherapy

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WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Yueshui Zhao[1,2] ; Xianmei Zhong[1,2,9] ; Fukuan Du[1,2] ; Xu Wu[1,2] ; Mingxing Li[1,2] ; Qinglian Wen[3] ; Jing Shen[1,2] ; Yu Chen[1,2] ; Xinyi Zhang[4] ; Zhongming Yang[5] ; Ying Deng[6] ; Xiang Liu[6] ; Chang Zou[7,*3] ; Yu Du[6,*2] ; Zhangang Xiao[1,8,*1] ;
机构： [1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, China. [2]South Sichuan Institute of Translational Medicine, Luzhou, Sichuan, China. [3]Department of Pharmacy, People's Hospital of Nanbu County, Nanchong, Sichuan China. [4]Department of Oncology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China. [5]School of Data Science, The Chinese University of Hong Kong, Shenzhen, China. [6]Department of Oncology and Hematology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China. [7]Medical Cosmetology Center, Affiliated of Traditional Chinese Medicine, Southwest Medical University, Luzhou, Sichuan, PR China. [8]Clinical Medical Research Center, the Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, PR China. [9]Cell Therapy & Cell Drugs of Luzhou Key Laboratory, Luzhou, Sichuan, China.
出处：
DOI： 10.2174/1574888X18666230103120302
ISSN：

关键词： Mesenchymal stem cells tumor cancer immunotherapy cytokine storm chimeric antigen receptor cellular immune cell therapy (CAR-T)

摘要：
Mesenchymal stem cells (MSCs) are getting attention in the field of cancer immunotherapy. The main effects of MSCs on tumors are homing and regulation of inflammatory and immune responses. Indeed, cancer immunotherapy has become a promising treatment and MSCs play a potential role in regulating the efficacy of immunotherapy. In addition, MSCs are an ideal carrier for immunomodulatory protein transmission. As such MSCs combined with immunotherapy drugs could act synergistically against tumors, throwing a great impact on cancer therapy. And MSCs may have potential in the treatment of cytokine storm or cytokine release syndrome (CRS). It is assumed that MSCs can form chimeric antigen receptor MSCs (CAR-MSCs). Whether CAR-MSCs can provide a new idea of cancer immunotherapy is unknown. It is a prime time to review the latest progress of MSCs in cancer immunotherapy, in order to clarify to fully understand the role of MSCs in cancer therapy in clinical practice.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

基金：
National Natural Science Foundation of China (Grant no.81972643) and Sichuan Science and Technology Project (Grant nos. 2018JY0079 and 2021YJ0201).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类 | 4 区 医学
小类 | 4 区 细胞与组织工程 4 区 细胞生物学
最新[2023]版：
大类 | 4 区 医学
小类 | 4 区 细胞与组织工程 4 区 细胞生物学
JCR分区：
出版当年[2023]版：
Q4 CELL & TISSUE ENGINEERING Q4 CELL BIOLOGY
最新[2023]版：
Q4 CELL & TISSUE ENGINEERING Q4 CELL BIOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

第一作者：
第一作者机构： [1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, China. [2]South Sichuan Institute of Translational Medicine, Luzhou, Sichuan, China.
共同第一作者：
通讯作者：
通讯机构： [1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, China. [6]Department of Oncology and Hematology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China. [7]Medical Cosmetology Center, Affiliated of Traditional Chinese Medicine, Southwest Medical University, Luzhou, Sichuan, PR China. [8]Clinical Medical Research Center, the Second Clinical Medical College of Jinan University, Shenzhen People's Hospital, Shenzhen, PR China. [*1]Laboratory of Molecular Pharmacology, School of Pharmacy, Department of Pharmacology, Southwest Medical University, Luzhou, Sichuan, China [*2]Medical Cosmetology Center, Affiliated of Traditional Chinese Medicine, Southwest Medical University, Luzhou, Sichuan, PR China [*3]Clinical Medical Research Center, the Second Clinical Medical College of Jinan University, Shenzhen People’s Hospital, Shenzhen, PR China
推荐引用方式(GB/T 7714)：
Yueshui Zhao,Xianmei Zhong,Fukuan Du,et al.The Role of Mesenchymal Stem Cells in Cancer Immunotherapy[J].CURRENT STEM CELL RESEARCH & THERAPY.2023,18(8):1056-1068.doi:10.2174/1574888X18666230103120302.
APA：
Yueshui Zhao,Xianmei Zhong,Fukuan Du,Xu Wu,Mingxing Li...&Zhangang Xiao.(2023).The Role of Mesenchymal Stem Cells in Cancer Immunotherapy.CURRENT STEM CELL RESEARCH & THERAPY,18,(8)
MLA：
Yueshui Zhao,et al."The Role of Mesenchymal Stem Cells in Cancer Immunotherapy".CURRENT STEM CELL RESEARCH & THERAPY 18..8(2023):1056-1068

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