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A Phase Ib/II Clinical Study of HRS-1167 in Combination With Bevacizumab in Patients With Recurrent Ovarian Cancer

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研究单位: [1]Jiangsu HengRui Medicine Co., Ltd. [2]First Affiliated Hospital of University of Science and Technology of China,Hefei,Anhui,China,230002 [3]Cancer Hospital Chinese Academy of Medical Sciences,Beijing,Beijing,China,100021 [4]Beijing Cancer Hospital,Beijing,Beijing,China,100142 [5]Chongqing University Cancer Hospital,Chongqing,Chongqing,China,400000 [6]The First Affiliated Hospital of Chongqing Medical University,Chongqing,Chongqing,China,400016 [7]Guangxi Medical University Affiliated Tumor Hospital,Nanning,Guangxi,China,530022 [8]The Fourth Hospital of Hebei Medical University,Shijiazhuang,Hebei,China,050001 [9]Harbin Medical University Cancer Hospital,Harbin,Heilongjiang,China,150001 [10]Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology,Wuhan,Hubei,China,430030 [11]Hunan Cancer Hospital,Changsha,Hunan,China,410013 [12]Liaoning Cancer Hospital,Shenyang,Liaoning,China,110042 [13]Qilu Hospital of Shandong University,Jinan,Shandong,China,250000 [14]Shandong First Medical University Affiliated Cancer Hospital,Jinan,Shangdong,China,250117 [15]Shanxi Provincial Cancer Hospital,Taiyuan,Shanxi,China,030006 [16]Sichuan Cancer Hospital,Chengdu,Sichuan,China,610042 [17]Tianjin Cancer Hospital,Tianjin,Tianjin,China,300000 [18]Yunnan Cancer Hospital,Kunming,Yunnan,China,650118 [19]Zhejiang Cancer Hospital,Hangzhou,Zhejiang,China,310005

研究目的:
This study is a multicenter, open-label Phase Ib/II clinical trial to observe and evaluate the safety, tolerability and pharmacokinetics of HRS-1167 in combination with bevacizumab in patients with recurrent ovarian cancer mechanical characterization and preliminary evaluation of the efficacy of HRS-1167 in combination with bevacizumab in patients with recurrent ovarian cancer.

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