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Neoadjuvant Chemotherapy Plus Camrelizumab for FIGO Stage IB1 Cervical Cancer

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研究单位: [1]Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan,Hubei,China,430030 [2]Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University [3]Women Hospital, School of Medicine, Zhejiang University [4]Third Military Medical University [5]Beijing Friendship Hospital [6]Sichuan Cancer Hospital and Research Institute [7]Tianjin Medical University [8]West China Second University Hospital [9]Xiangya Hospital of Central South University [10]Qilu Hospital of Shandong University [11]Gansu Cancer Hospital [12]Zhejiang Cancer Hospital [13]Shengjing Hospital [14]Anhui Provincial Cancer Hospital

研究目的:
This multicenter, prospective clinical trial is designed to enroll PD-L1 expression-positive patients with stage IB1 cervical cancer who desire fertility preservation to undergo neoadjuvant chemotherapy in combination with a PD-1 inhibitor to evaluate the rate of complete pathologic remission, treatment-related adverse events, pregnancy rate, miscarriage rate, preterm birth rate, live birth rate, PFS and OS.

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