研究单位：[1]Merck Sharp & Dohme LLC[2]European Network for Gynaecological Oncological Trial groups(ENGOT)[3]GOG Foundation[4]USA Mitchell Cancer Institute ( Site 4142),Mobile,Alabama,United States,36604[5]Alaska Womens Cancer Care ( Site 4122),Anchorage,Alaska,United States,99508[6]UCLA Hematology/Oncology - Westwood (Building 100)-Department of OBGYN, Division of Gynecologic Onc,Los Angeles,California,United States,90095[7]California Pacific Medical Center - Van Ness Campus ( Site 4129),San Francisco,California,United States,94109[8]Yale-New Haven Hospital-Smilow Cancer Hospital at Yale-New Haven ( Site 4114),New Haven,Connecticut,United States,06511[9]MedStar Washington Hospital Center ( Site 4108),Washington,District of Columbia,United States,20010[10]Mount Sinai Cancer Center ( Site 4117),Miami Beach,Florida,United States,33140[11]AdventHealth Orlando-AdventHealth Medical Group Gynecological Oncology ( Site 4113),Orlando,Florida,United States,32804[12]Centricity Research Columbus Cancer Center ( Site 4154),Columbus,Georgia,United States,31904[13]NorthShore University HealthSystem - Evanston Hospital ( Site 4110),Evanston,Illinois,United States,60201[14]Parkview Research Center at Parkview Regional Medical Center ( Site 4132),Fort Wayne,Indiana,United States,46845[15]University Medical Center New Orleans ( Site 4133),New Orleans,Louisiana,United States,70112[16]TRIALS 365 ( Site 4105),Shreveport,Louisiana,United States,71103[17]University of Massachusetts Memorial Medical Center ( Site 4103),Worcester,Massachusetts,United States,01605[18]Washington University School of Medicine-Obstetrics & Gynecology ( Site 4146),Saint Louis,Missouri,United States,63110[19]The Center of Hope ( Site 4109),Reno,Nevada,United States,89511[20]John Theurer Cancer Center at Hackensack University Medical Center ( Site 4118),Hackensack,New Jersey,United States,07601[21]Atlantic Health System Morristown Medical Center ( Site 4135),Morristown,New Jersey,United States,07960[22]Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 4156),Mineola,New York,United States,11501[23]Laura and Isaac Perlmutter Cancer Center ( Site 4106),New York,New York,United States,10016[24]Icahn School of Medicine at Mount Sinai-Department of Obstetrics, Gynecology, and Reproductive Scie,New York,New York,United States,10029[25]Good Samaritan Hospital Medical Center ( Site 4139),West Islip,New York,United States,11795[26]Duke Cancer Institute ( Site 4120),Durham,North Carolina,United States,27710[27]Sanford Health Roger Maris Cancer Center ( Site 4158),Fargo,North Dakota,United States,58102[28]University of Cincinnati Medical Center ( Site 4136),Cincinnati,Ohio,United States,45219[29]The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C,Columbus,Ohio,United States,43210[30]Sidney Kimmel Cancer Center - Jefferson Health ( Site 4157),Philadelphia,Pennsylvania,United States,19107[31]AHN West Penn Hospital-Gynecologic Oncology ( Site 4111),Pittsburgh,Pennsylvania,United States,15244[32]Asplundh Cancer Pavilion ( Site 4107),Willow Grove,Pennsylvania,United States,19090[33]Women & Infants Hospital ( Site 4138),Providence,Rhode Island,United States,02905[34]Sanford Cancer Center-Gynecologic Oncology ( Site 4121),Sioux Falls,South Dakota,United States,57104[35]The West Clinic, PLLC dba West Cancer Center ( Site 4102),Germantown,Tennessee,United States,38138[36]Houston Methodist Hospital-Obstetrics and Gynecology ( Site 4130),Houston,Texas,United States,77030[37]Hospital Británico de Buenos Aires-Oncology ( Site 1002),Ciudad autónoma de Buenos Aires,Buenos Aires,Argentina,C1280AEB[38]Instituto Argentino de Diagnóstico y Tratamiento (IADT) ( Site 1008),Buenos Aires,Caba,Argentina,C1122AAL[39]Instituto Alexander Fleming-Alexander Fleming ( Site 1007),Ciudad Autónoma de Buenos Aires,Caba,Argentina,1426[40]Hospital Aleman-Oncology ( Site 1001),Buenos Aires,Argentina,C1118AAT[41]Instituto de Oncología Angel H. Roffo ( Site 1003),Buenos Aires,Argentina,C1417DTB[42]Centro de Educación Médica e Investigaciones Clínicas (CEMIC) ( Site 1004),Buenos Aires,Argentina,C1431FWO[43]Fundación CORI para la Investigación y Prevención del Cáncer ( Site 1006),La Rioja,Argentina,F5300COE[44]GenesisCare North Shore ( Site 1103),St Leonards,New South Wales,Australia,2065[45]Blacktown Hospital ( Site 1101),Sydney,New South Wales,Australia,2148[46]Royal Brisbane and Women's Hospital ( Site 1102),Brisbane,Queensland,Australia,4029[47]Epworth Freemasons ( Site 1104),East Melbourne,Victoria,Australia,3002[48]Frankston Hospital ( Site 1105),Frankston,Victoria,Australia,3199[49]Medizinische Universitaet Innsbruck-Univ.-Klinik f. Gynäkologie und Geburtshilfe ( Site 1201),Innsbruck,Tirol,Austria,6020[50]Medizinische Universität Wien ( Site 1202),Wien,Austria,1090[51]AZ Maria Middelares-IKG ( Site 1305),Gent,Oost-Vlaanderen,Belgium,9000[52]UZ Gent-Medical oncology ( Site 1303),Gent,Oost-Vlaanderen,Belgium,9000[53]UZ Leuven-Gynecologic Oncology ( Site 1301),Leuven,Vlaams-Brabant,Belgium,3000[54]AZ Delta vzw-Oncology ( Site 1302),Roeselare,West-Vlaanderen,Belgium,8800[55]CHU UCL Namur/Site Sainte Elisabeth-Trial Office ( Site 1304),Namur,Belgium,5000[56]Hospital São Domingos ( Site 1365),Sao Luis,Maranhao,Brazil,65060-645[57]Centro Oncologico do Triangulo ( Site 1360),Uberlândia,Minas Gerais,Brazil,38408-150[58]Hospital Moinhos de Vento ( Site 1359),Porto Alegre,Rio Grande Do Sul,Brazil,90035-001[59]Instituto Joinvilense de Hematologia e Oncologia ( Site 1353),Joinville,Santa Catarina,Brazil,89201260[60]Instituto de Ensino e Pesquisa ( Site 1355),Sorocaba,Sao Paulo,Brazil,18060-105[61]Instituto de Educação, Pesquisa e Gestão em Saúde ( Site 1352),Rio de Janeiro,Brazil,20775-001[62]A. C. Camargo Cancer Center ( Site 1351),Sao Paulo,Brazil,01509-010[63]BC Cancer Vancouver ( Site 1415),Vancouver,British Columbia,Canada,V5Z 4E6[64]CIUSSS- saguenay-Lac-Saint-Jean ( Site 1408),Chicoutimi,Quebec,Canada,G7H 5H6[65]Centre Hospitalier de l'Université de Montréal ( Site 1403),Montréal,Quebec,Canada,H2X 0C1[66]McGill University Health Centre ( Site 1404),Montréal,Quebec,Canada,H4A 3J1[67]James Lind Centro de Investigacion del Cancer ( Site 1504),Temuco,Araucania,Chile,4800827[68]Centro de Estudios Clínicos SAGA-CECSAGA ( Site 1505),Santiago,Region M. De Santiago,Chile,7501010[69]Pontificia Universidad Catolica de Chile ( Site 1503),Santiago,Region M. De Santiago,Chile,8330032[70]Bradfordhill-Clinical Area ( Site 1501),Santiago,Region M. De Santiago,Chile,8420383[71]Sun Yat-sen University Cancer Center ( Site 1604),Guangzhou,Guangdong,China,510555[72]Cancer Hospital of Shantou University Medical College ( Site 1642),Shantou,Guangdong,China,515041[73]Affiliated Hospital of Guangdong Medical University ( Site 1614),Zhanjiang,Guangdong,China,524004[74]Guangxi Medical University Affiliated Tumor Hospital-Gynecological oncology ( Site 1622),Nanning,Guangxi,China,530021[75]Henan Cancer Hospital ( Site 1618),Zhengzhou,Henan,China,450008[76]The Second Affiliated Hospital of Zhengzhou University ( Site 1640),Zhengzhou,Henan,China,450014[77]Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1621),Wuhan,Hubei,China,430010[78]Hubei Cancer Hospital-Hubei Cancer Hospital ( Site 1607),Wuhan,Hubei,China,430079[79]Nanjing First Hospital ( Site 1649),Nanjing,Jiangsu,China,210006[80]Jiangxi Maternal and Child Health Hospital-Oncology Department ( Site 1625),Nanchang,Jiangxi,China,330006[81]Shanghai First Maternity and Infant Hospital-Gynecology department ( Site 1626),Shanghai,Shanghai,China,201204[82]West China Second University Hospital, Sichuan University ( Site 1602),Chengdu,Sichuan,China,610000[83]Sichuan Cancer hospital-Oncology ( Site 1650),Chengdu,Sichuan,China,610042[84]Xinjiang Medical University Cancer Hospital - Urumqi ( Site 1648),Urumqi,Xinjiang,China,830000
Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with platinum based therapy (a type of chemotherapy) and immunotherapy. Immunotherapy is a treatment that helps the immune system fight cancer. This clinical study will compare MK-2870 sacituzumab tirumotecan to chemotherapy. The goal of the study is to learn if people who receive MK-2870 sacituzumab tirumotecan live longer overall and without the cancer getting worse compared to people who receive chemotherapy.
