A Study of LY3537982 Plus Immunotherapy With or Without Chemotherapy in Participants With Non-Small Cell Lung Cancer (NSCLC) With a Change in a Gene Called KRAS G12C
研究单位:[1]Loxo Oncology, Inc.[2],Korea, Republic of,28644[3],Korea, Republic of,02841[4],Korea, Republic of,03722[5],Korea, Republic of,05505[6],Korea, Republic of,07345[7],Korea, Republic of,08308[8],Korea, Republic of,4763[9]Hospital Pulido Valente,Lisbon,Lisboa,Portugal,1769-001[10]Centro Hospitalar E Universitário De Coimbra,Coimbra,Portugal,3040[11]Hospital da Luz Lisboa,Lisboa,Portugal,1500-650[12]Centro Hospitalar do Porto - Hospital de Santo António,Porto,Portugal,4099-001[13]Hospital CUF Porto,Porto,Portugal,4100-180[14]Instituto Português de Oncologia do Porto Francisco Gentil, EPE,Porto,Portugal,4200-072[15]Lotus-Med,Bucharest,Bucuresti,Romania,012292[16]Institutul Oncologic,Cluj-Napoca,Cluj,Romania,400015[17]Ovidius Clinical Hospital OCH,Ovidiu,Constanța,Romania,905900[18]"Centrul de Oncologie ""Sfântul Nectarie"",Craiova,Dolj,Romania,200542[19]"S C Oncocenter Oncologie Clinica S R L,Timișoara,Timiș,Romania,300166[20]Cabinet Medical Oncomed,Timișoara,Timiș,Romania,300239[21]Centrul medical Focus,București,Romania,022548[22]Gral Medical Diagnostic Center,București,Romania,031422[23]CHUS - Hospital Clinico Universitario,Santiago de Compostela,A Coruña ,Spain,15706[24]CHUAC-Hospital Teresa Herrera,A Coruña,A Coruña [,Spain,15006[25]Hospital Universitari Son Espases,Palma De Mallorca,Balears ,Spain,07120[26]Parc de Salut Mar - Hospital del Mar,Barcelona,Barcelona ,Spain,08003[27]Hospital Universitari Vall d'Hebron,Barcelona,Barcelona ,Spain,8035[28]Instituto Catalan de Oncologia - Hospital Duran I Reynals,Hospitalet de Llobregat,Barcelona ,Spain,8907[29]Complejo Asistencial Universitario de León - Hospital de León,León,Castilla Y León,Spain,24071[30]Hospital Universitari Dexeusa,Barcelona,Catalunya ,Spain,08028[31]Hospital Jerez de la Frontera,Jerez De La Frontera,Cádiz,Spain,11407[32]Hospital Insular de Gran Canaria,Las Palmas de Gran Canaria,Las Palmas,Spain,35016[33]Hospital Universitario Ramón y Cajal,Madrid,Madrid, Comunidad De,Spain,28034[34]Hospital Universitario 12 de Octubre,Madrid,Madrid, Comunidad De,Spain,28041[35]Hospital Universitario Quironsalud Madrid,Pozuelo de Alarcon,Madrid,Spain,28223[36]Complejo Hospitalario de Navarra,Pamplona,Navarra,Spain,31009[37]Hospital Clinico de Valencia,Valencia,Valenciana, Comunitat,Spain,46010[38]Hospital Infanta Cristina,Badajoz,Spain,06006[39]Hospital Regional Universitario,Málaga,Spain,29011[40]Hospital Universitario Virgen Del Rocio,Sevilla,Spain,41013[41]Akademiska sjukhuset,Uppsala,Uppsala Län ,Sweden,751 85[42]Västmanlands Sjukhus Västerås,Västerås,Västmanlands Län ,Sweden,721 89[43]Kantonsspital Winterthur,Winterthur,Switzerland,8401[44]UniversitätsSpital Zürich,Zürich,Switzerland,8091[45]Changhua Christian Hospital,Changhua County,Changhua,Taiwan,50006[46]Hualien Tzu Chi Medical Center,Hualien City,Hualien,Taiwan,970[47]Chung Shan Medical University Hospital,Taichung City,Taichung,Taiwan,402[48]Chi Mei Hospital - Liouying Branch,Tainan City,Tainan,Taiwan,73657[49]National Taiwan University Cancer Center (NTUCC),Taipei City,Taipei,Taiwan,106[50]National Taiwan University Hospital Yun-Lin Branch Dou-Liou Region,Douliu City,Yunlin,Taiwan,640[51]Buddhist Dalin Tzu Chi General Hospital,Chiayi,Taiwan,622[52]Kaohsiung Medical University Hospital,Kaohsiung,Taiwan,807[53]Chang Gung Memorial Hospital at Kaohsiung,Kaohsiung,Taiwan,83301[54]Taichung Veterans General Hospital,Taichung,Taiwan,407[55]National Cheng Kung University Hospital,Tainan,Taiwan,704[56]National Taiwan University Hospital,Taipei,Taiwan,10002[57]Taipei Veterans General Hospital,Taipei,Taiwan,11217[58]Chang Gung Medical Foundation-Linkou Branch,Taoyuan,Taiwan,333[59]Adana Medical Park Seyhan Hastanesi,Adana,Turkey,01140[60]Adana City Hospital,Adana,Turkey,01370[61]Ankara Etlik City Hospital,Ankara,Turkey,06170[62]Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi,Ankara,Turkey,06200[63]Ankara City Hospital,Ankara,Turkey,06800[64]Akdeniz Universitesi Hastanesi,Antalya,Turkey,07059[65]Memorial Antalya Hospital,Antalya,Turkey,07090[66]Uludag Universitesi,Bursa,Turkey,16059[67]Dicle Üniversitesi,Diyarbakir,Turkey,21200[68]Bezmialem Vakf Üniversitesi,Istanbul,Turkey,34093[69]TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi,Istanbul,Turkey,34722[70]Ege Universitesi Hastanesi,Izmir,Turkey,35100[71]zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi,Izmir,Turkey,35360[72]Ophthalmology,Kocaeli,Turkey,41380[73]Ondokuz Mayıs Universitesi,Samsun,Turkey,55139[74]Aberdeen Royal Infirmary,Aberdeen,Aberdeen City,United Kingdom,AB25 2ZN[75]Ninewells Hospital and Medical School,Dundee,Angus,United Kingdom,DD1 9SY[76]Weston Park Hospital,Sheffield,England,United Kingdom,S10 2SJ[77]Cheltenham General Hospital,Cheltenham,Gloucestershire,United Kingdom,GL53 7AN[78]Mount Vernon Hospital,Northwood,Hillingdon,United Kingdom,HA6 2RN[79]The Christie NHS Foundation Trust,Manchester,Withington,United Kingdom,M20 4 BX[80]St James's University Hospital,Leeds,United Kingdom,LS9 7TF[81]New Cross Hospital,Wolverhampton,United Kingdom,WV10 0QP[82]Clearview Cancer Institute,Huntsville,Alabama,United States,35805[83]St. Joseph's Hospital and Medical Center,Phoenix,Arizona,United States,85004[84]The University of Arizona Cancer Center - North Campus,Tucson,Arizona,United States,85719[85]Highlands Oncology Group,Springdale,Arkansas,United States,72762[86]Cedars-Sinai Medical Center,Los Angeles,California,United States,90048[87]Mercy UC Davis Cancer Center,Merced,California,United States,95340[88]Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center,Torrance,California,United States,90502[89]USO - Rocky Mountain Cancer Centers,Lone Tree,Colorado,United States,80124[90]Yale University School of Medicine,New Haven,Connecticut,United States,06510[91]Sibley Memorial Hospital,Washington,District of Columbia,United States,20016[92]Millennium Oncology - Hollywood,Hollywood,Florida,United States,33024[93]Miami Cancer Institute at Baptist Health, Inc.,Miami,Florida,United States,33176[94]Ocala Oncology Center PL DBA Florida Cancer Affiliates - Ocala,Ocala,Florida,United States,34474[95]Comprehensive Hematology Oncology,Saint Petersburg,Florida,United States,33709[96]Tampa General Hospital,Tampa,Florida,United States,33606[97]Winship Cancer Institute, Emory University,Atlanta,Georgia,United States,30322[98]University of Illinois at Chicago,Chicago,Illinois,United States,60612-7230[99]University of Illinois at Chicago,Chicago,Illinois,United States,60612[100]University of Chicago Hospital,Chicago,Illinois,United States,60637[101]Springfield Clinic Main Campus,Springfield,Illinois,United States,62702[102]Indiana University Melvin and Bren Simon Cancer Center,Indianapolis,Indiana,United States,46202[103]Community Cancer Center North,Indianapolis,Indiana,United States,46250[104]The University of Kansas Cancer Center - Westwood,Westwood,Kansas,United States,66205[105]University of Kentucky Chandler Medical Center,Lexington,Kentucky,United States,40536[106]USO - Maryland Oncology Hematology,Annapolis,Maryland,United States,21401[107]Johns Hopkins Bayview Medical Center,Baltimore,Maryland,United States,21224[108]Boston Medical Center,Boston,Massachusetts,United States,02118[109]Lahey Hospital & Medical Center,Burlington,Massachusetts,United States,01805[110]University of Michigan,Ann Arbor,Michigan,United States,48109[111]Karmanos Cancer Institute,Detroit,Michigan,United States,48201[112]Cancer and Hematology Centers of Western Michigan,Grand Rapids,Michigan,United States,49503[113]Allina Health Cancer Institute,Minneapolis,Minnesota,United States,55407[114]HealthPartners Cancer Research Center,Saint Paul,Minnesota,United States,55101[115]Saint Louis University Cancer Center,Saint Louis,Missouri,United States,63110[116]Mercy Research,Saint Louis,Missouri,United States,63141[117]Dartmouth-Hitchcock Medical Center,Lebanon,New Hampshire,United States,03756[118]Summit Health,Florham Park,New Jersey,United States,07932[119]The Valley Hospital,Paramus,New Jersey,United States,07652[120]Capital Health Medical Center - Hopewell,Pennington,New Jersey,United States,08534[121]The Valley Hospital,Ridgewood,New Jersey,United States,07450[122]University of New Mexico Comprehensive Cancer Center,Albuquerque,New Mexico,United States,87131[123]New York Cancer and Blood Specialists - New Hyde Park,Bronx,New York,United States,10469[124]Perlmutter Cancer Center at NYU Langone Hospital - Long Island,Mineola,New York,United States,11501[125]Laura and Isaac Perlmutter Cancer Center,New York,New York,United States,10016[126]Manhattan Eye, Ear and Throat Hospital,New York,New York,United States,10065[127]Memorial Sloan Kettering Cancer Center,New York,New York,United States,10065[128]Clinical Research Alliance,Westbury,New York,United States,11590[129]University of North Carolina Medical Center,Chapel Hill,North Carolina,United States,27599[130]Duke Cancer Institute,Durham,North Carolina,United States,27710[131]USO - Oncology Associates of Oregon,Eugene,Oregon,United States,97401[132]Asante Rogue Regional Medical Center,Medford,Oregon,United States,97504[133]Providence Portland Medical Center,Portland,Oregon,United States,97213[134]Kaiser Permanente Interstate Medical Office Central,Portland,Oregon,United States,97227[135]Bryn Mawr Hospital,Bryn Mawr,Pennsylvania,United States,19010[136]USO - Alliance Cancer Specialists, PC,Horsham,Pennsylvania,United States,19044[137]Riddle Hospital,Media,Pennsylvania,United States,19063[138]Paoli Memorial Hospital,Paoli,Pennsylvania,United States,19301[139]Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office,Philadelphia,Pennsylvania,United States,19107[140]UPMC Hillman Cancer Center,Pittsburgh,Pennsylvania,United States,15232[141]Lankenau Medical Center,Wynnewood,Pennsylvania,United States,19096[142]Medical University of South Carolina,Charleston,South Carolina,United States,29425[143]Prisma Health Cancer Institute,Greenville,South Carolina,United States,29605[144]Tidelands Health Oncology,Murrells Inlet,South Carolina,United States,29576[145]Baptist Memorial Hospital-Memphis,Memphis,Tennessee,United States,38120[146]William Beaumont Army Medical Center,Fort Bliss,Texas,United States,79918[147]Brooke Army Medical Center,Fort Sam Houston,Texas,United States,78234[148]Houston Methodist Hospital,Houston,Texas,United States,77030[149]University of Texas MD Anderson Cancer Center,Houston,Texas,United States,77030[150]Baylor Scott & White Medical Center - Temple,Temple,Texas,United States,76508[151]The University of Vermont Medical Center Inc.,Burlington,Vermont,United States,05401[152]VCU Health Adult Outpatient Pavillion,Richmond,Virginia,United States,23219[153]Kadlec Clinic Hematology and Oncology,Kennewick,Washington,United States,99336[154]Virginia Mason Medical Center,Seattle,Washington,United States,98101[155]Swedish Medical Center,Seattle,Washington,United States,98104[156]VA Puget Sound Health Care System,Seattle,Washington,United States,98108[157]Gosford Hospital,Gosford,New South Wales,Australia,2250[158]Icon Cancer Centre Wesley,Auchenflower,Queensland,Australia,4066[159]Sunshine Coast University Hospital,Birtinya,Queensland,Australia,4575[160]Mackay Base Hospital,Mackay,Queensland,Australia,4740[161]Gold Coast University Hospital,Southport,Queensland,Australia,4215[162]The Townsville Hospital,Townsville,Queensland,Australia,4814[163]Royal Adelaide Hospital,Adelaide,South Australia,Australia,5000[164]Ballarat Health Services,Ballarat Central,Victoria,Australia,3350[165]St Vincent's Hospital,Melbourne,Victoria,Australia,3065[166]Goulburn Valley Health,Shepparton,Victoria,Australia,3630[167]Sir Charles Gairdner Hospital,Perth,Western Australia,Australia,6009[168]Ordensklinikum Linz GmbH Elisabethinen,Linz,Oberösterreich,Austria,4020[169]Landeskrankenhaus Feldkirch,Feldkirch,Vorarlberg,Austria,6800[170]Klinik Floridsdorf,Wien,Austria,1210[171]ZNA Middelheim,Antwerp,Antwerpen,Belgium,2020[172]AZ Sint-Maarten, Campus Leopoldstraat 2,Mechelen,Antwerpen,Belgium,2800[173]Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godinne,Yvoir,Namur,Belgium,5000[174]UZ Gent,Gent,Oost-Vlaanderen,Belgium,9000[175]UZ Leuven,Leuven,Vlaams-Brabant,Belgium,3000[176]AZ Sint-Jan Brugge-Oostende AV,Brugge,West-Vlaanderen,Belgium,8000[177]AZ Groeninge Campus Kennedylaan,Kortrijk,West-Vlaanderen,Belgium,8500[178]Clinique Saint Pierre,Ottignies,Belgium,1340[179]AZ Glorieux Ronse,Ronse,Belgium,9600[180]Clinica Amo - Rio Vermelho,Salvador,Bahia,Brazil,41950-640[181]Centro de Pesquisa Clínica do Instituto do Câncer do Ceará,Fortaleza,Ceará,Brazil,60430235[182]Sirio-Libanes Brasilia - Centro de Oncologia - Asa Sul,Brasilia,Distrito Federal,Brazil,70200-730[183]Hospital Brasilia,Lago sul,Distrito Federal,Brazil,71635580[184]Hospital São Domingos,Bequimao,Maranhão,Brazil,65060-645[185]Oncominas,Pouso Alegre,Minas Gerais,Brazil,37554-216[186]Hospital Universitário Evangélico Mackenzie,Curitiba,Parana,Brazil,80730-150[187]Hospital de Cancer de Londrina,Londrina,Paraná,Brazil,86015-520[188]Liga Norte Riograndense Contra o Câncer,Natal,Rio Grande Do Norte,Brazil,59062-000[189]Hospital Tacchini,Bento Gonçalves,Rio Grande Do Sul,Brazil,95700-084[190]ONCOSITE - Centro de Pesquisa Clinica em Oncologia,Ijui,Rio Grande Do Sul,Brazil,98700-000[191]Hospital São Lucas da PUCRS,Porto Alegre,Rio Grande Do Sul,Brazil,90610[192]Faculdade de Medicina do ABC,Santo André,São Paulo,Brazil,09060-650[193]Hospital BP,Sao Paulo,São Paulo,Brazil,01321-001[194]Hospital Paulistano,Sao Paulo,São Paulo,Brazil,01321-001[195]Instituto D'Or de Pesquisa e Ensino (IDOR),Sao Paulo,São Paulo,Brazil,04543-000[196]COE Ensino e Pesquisa,São José dos Campos,São Paulo,Brazil,12242-660[197]Instituto Nacional de Câncer - INCA,Rio de Janeiro,Brazil,20231-050[198]Grupo Oncoclínicas Botafogo,Rio de Janeiro,Brazil,22250-905[199]Icesp - Instituto Do Câncer Do Estado de São Paulo,São Paulo,Brazil,01246-000[200]Hospital Sírio Libanês,São Paulo,Brazil,01308-060[201]Centro Paulista de Oncologia Clínica,São Paulo,Brazil,01452-000[202]Núcleo de Pesquisa Clínica da Rede São Camilo,São Paulo,Brazil,04014-002[203]Instituto de Assist├ncia M├dica ao Servidor P,São Paulo,Brazil,04039-901[204]BC Cancer Vancouver,Vancouver,British Columbia,Canada,V5Z 4E6[205]CIUSSS- saguenay-Lac-Saint-Jean,Chicoutimi,Quebec,Canada,G7H 5H6[206]Unité de Recherche Clinique du CISSS des Laurentides,Saint-Jérôme,Quebec,Canada,J7Z 2V4[207]Wannan Medical College Yijishan Hospital,Wuhu,Anhui,China,241001[208]Cancer Hospital Chinese Academy of Medical Science,Beijing,Beijing,China,100021[209]Beijing Cancer hospital,Beijing,Beijing,China,100142[210]The First Affiliated Hospital of the Third Military Medical University,Shapingba,Chongqing,China,400038[211]Fujian Provincial Cancer Hospital,Fuzhou,Fujian,China,350014[212]The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong,China,510120[213]The First Affiliated Hospital, Sun Yat-sen University,Guangzhou,Guangdong,China[214]Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong,China,524004[215]Liuzhou People's Hospital,Liuzhou,Guangxi,China,545006[216]Hainan General Hospital,Haikou,Hainan,China,570311[217]Harbin Medical University Cancer Hospital,Harbin,Heilongjiang,China,150081[218]The First Affiliated Hospital of Xinxiang Medical University,Xinxiang,Henan,China,453100[219]Wuhan Union Hospital,Wuhan,Hubei,China,430022[220]Tongji Hospital Tongji Medical,Science & Technology,Wuhan,Hubei,China,430030[221]Renmin Hospital of Wuhan University,Wuhan,Hubei,China,430060[222]Xiangyang Central Hospital,Xiangyang,Hubei,China,441021[223]Yichang Central People's Hospital,Yichang,Hubei,China,443003[224]Xiangya Hospital Central South University,Changsha,Hunan,China,410008[225]Hunan Cancer Hospital,Changsha,Hunan,China,410013[226]ZhuZhou Central Hospital,Zhuzhou,Hunan,China,412007[227]The First People's Hospital of Changzhou,Changzhou,Jiangsu,China,213003[228]Nanjing First Hospital,Nanjing,Jiangsu,China,210012[229]Jiangsu Province Hospital,Nanjing,Jiangsu,China,210029[230]Nantong Tumor Hospital,Nantong,Jiangsu,China,226361[231]The First Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,China,330006[232]Jilin Cancer Hospital,Changchun,Jilin,China,132000[233]Tangdu Hospital of Fourth Military Medical University of Chinese People's Liberation Army,Xi'an,Shaanxi,China,710038[234]The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,Shaanxi,China,710061[235]Jinan Central Hospital,Jinan,Shandong,China,250013[236]Shanghai Chest Hospital,Shanghai,Shanghai,China,200030[237]Zhongshan Hospital,Fudan University,Shanghai,Shanghai,China,200032[238]The Third People's Hospital of Chengdu (CDTPH),Chengdu,Sichuan,China,610031[239]Tianjin Medical University Cancer Institute and Hospital,Tianjin,Tianjin,China,300060[240]The First Affiliated Hospital of Xinjiang Medical University,Urumchi,Xinjiang,China,830054[241]Xinjiang Medical University Cancer Hospital - Urumqi,Urumqi,Xinjiang,China,830000[242]The First Affiliated Hospital, Zhejiang University,Hangzhou,Zhejiang,China,310003[243]Sir Run Run Shaw Hospital,Hangzhou,Zhejiang,China,310016[244]Zhejiang Cancer Hospital,Hangzhou,Zhejiang,China,310022[245]Taizhou Hospital of Zhejiang Province,Linhai,Zhejiang,China,317099[246]Hwa Mei Hospital University of Chinese Academy of Sciences,Ningbo,Zhejiang,China,315099[247]Sichuan Cancer hospital,Chengdu,China,610041[248]Yichang Central People's Hospital,Yichang,China,443003[249]Nemocnice AGEL Ostrava - Vitkovice a.s.,Ostrava,Ostrava Mě,Czechia,703 84[250]Fakultni nemocnice Bulovka,Prague,Praha 8,Czechia,180 81[251]Næstved Sygehus,Næstved,Sjælland,Denmark,4700[252]Roskilde University Hospital,Roskilde,Sjælland,Denmark,4000[253]Centre Antoine-Lacassagne,Nice,Alpes-Maritimes,France,06189[254]Nouvel Hôpital Civil (NHC),Strasbourg,Alsace,France,67091[255]CHU Bordeaux Haut-Leveque,Pessac,Aquitaine,France,33600[256]CHU de Toulouse - Hopital Larrey,Toulouse,Haute-Garonne,France,31059[257]Hôpital Foch,Suresnes,Hauts-de-Seine,France,92151[258]Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou,Rennes,Ille-et-Vilaine,France,35033[259]Centre de Cancérologie du Grand Montpellier,Montpellier,Languedoc-Roussillon,France,34070[260]Institut de Cancérologie de l'Ouest,Saint Herblain,Loire-Atlantique,France,44805[261]Hôpital Robert Schuman,Vantoux,Lorraine,France,57070[262]Institut Jean Godinot,Reims,Marne,France,51726[263]CHU Lille - Institut Coeur Poumon,Lille Cedex,Nord,France,59037[264]Centre Hospitalier intercommunal de Toulon La Seyne sur Mer,Toulon,Provence-Alpes-Côte-d'Azur,France,83100[265]Centre Leon Berard,Lyon,Rhône-Alpes,France,69373[266]Hospices Civils de Lyon - Hopital Louis Pradel,Bron,Rhône,France,69677[267]Gustave Roussy,Villejuif,Val-de-Marne,France,94800[268]Sainte Catherine Institut du Cancer Avignon Provence,Avignon,Vaucluse,France,84918[269]Centre Hospitalier Universitaire de Poitiers,Poitiers,Vienne,France,86021[270]Institut Curie,Paris,France,75248[271]Universitaetsklinikum Freiburg,Freiburg,Baden-Württemberg,Germany,79106[272]Thoraxklinik-Heidelberg gGmbH,Heidelberg,Baden-Württemberg,Germany,69126[273]Universitaetsklinikum Tuebingen,Tübingen,Baden-Württemberg,Germany,72076[274]Asklepios Fachkliniken München-Gauting,Gauting,Bayern,Germany,82131[275]Klinikum Nürnberg Nord,Nürnberg,Bayern,Germany,90419[276]Universitätsklinikum Münster - Albert Schweitzer Campus,Münster,Nordrhein-Westfalen,Germany,48149[277]Krankenhaus Martha-Maria Halle-Dölau,Halle,Sachsen-Anhalt,Germany,06120[278]LungenClinic Grosshansdorf,Grosshansdorf,Schleswig-Holstein,Germany,22927[279]Städtisches Krankenhaus Kiel,Kiel,Schleswig-Holstein,Germany,24116[280]SRH Wald-Klinikum Gera,Gera,Thüringen,Germany,07548[281]Evangelische Lungenklinik Berlin,Berlin,Germany,13125[282]Charité Campus Virchow-Klinikum,Berlin,Germany,13353[283]Helios Klinikum Emil von Behring Berlin-Zehlendorf,Berlin,Germany,14165[284]Hämato-Onkologie Hamburg, Prof. Laack und Partner,Hamburg,Germany,20251[285]University Hospital of Patras,Patras,Achaḯa,Greece,26504[286]Agios Savvas Regional Cancer Hospital,Athens,Attikí,Greece,115 22[287]Errikos Dunant Hospital Center,Athens,Attikí,Greece,115 26[288]Sotiria Thoracic Diseases Hospital of Athens,Athens,Attikí,Greece,115 27[289]University General Hospital of Heraklion,Heraklion,Irakleío,Greece,715 00[290]European Interbalkan Medical Center,Thessaloniki,Thessaloníki,Greece,570 01[291]G. Papanikolaou General Hospital,Thessaloniki,Thessaloníki,Greece,570 10[292]Bacs-Kiskun Varmegyei Oktatokorhaz,Kecskemét,Bács-Kiskun,Hungary,6000[293]Országos Korányi Pulmonológiai Intézet,Budapest,Pest,Hungary,1121[294]Farkasgyepui Tudogyogyintezet,Farkasgyepű,Veszprém,Hungary,8582[295]Országos Onkológiai Intézet,Budapest,Hungary,1122[296]Uzsoki Utcai Kórház,Budapest,Hungary,1145[297]Rajiv Gandhi Cancer Institute And Research Centre,New Delhi,Delhi,India,110085[298]KLES Dr. Prabhakar Kore Hospital & M.R.C,Belagave,Karnataka,India,590010[299]SRV Hospitals,Bengaluru,Karnataka,India,560027[300]Regional Cancer Centre - Thiruvananthapuram,Thiruvananthapuram,Kerala,India,695011[301]Krishna Institute of Medical Sciences - Karad,Karad,Maharashtra,India,415539[302]Kolhapur Cancer Centre Private Limited,Kolhāpur,Maharashtra,India,416234[303]Tata Memorial Hospital,Mumbai,Maharashtra,India,400012[304]HCG Manavata Cancer Centre,Nashik,Maharashtra,India,422001[305]Grant Medical Foundation - Ruby Hall Clinic,Pune,Maharashtra,India,411001[306]Sahyadri Super Speciality Hospital,Pune,Maharashtra,India,411004[307]All India Institute of Medical Sciences,Bhubaneswar,Odisha,India,751019[308]Ashwin Hospital,Coimbatore,Tamil Nadu,India,641012[309]Nizam's Institute of Medical Sciences,Hyderabad,Telangana,India,500082[310]Tata Memorial Centre - Homi Bhabha Cancer Hospital,Varanasi,Uttar Pradesh,India,221002[311]Banaras Hindu University,Varanasi,Uttar Pradesh,India,221005[312]Tata Medical Center,Kolkata,West Bengal,India,700160[313]Postgraduate Institute of Medical Education & Research,Chandigarh,India,160012[314]Jawaharlal Institute Of Postgraduate Medical Education And Research,Puducherry,India,605006[315]Istituto Nazionale Tumori IRCCS Fondazione Pascale,Napoli,Campania,Italy,80131[316]Fondazione Policlinico Universitario Agostino Gemelli,Roma,Lazio,Italy,00168[317]Fondazione IRCCS Istituto Nazionale dei Tumori,Milan,Lombardia,Italy,20133[318]Istituto Nazionale Tumori Regina Elena,Rome,Roma,Italy,00144[319]"Policlinico ""G. Rodolico"",Catania,Sicilia,Italy,95123[320]"Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento,Verona,Veneto,Italy,37126[321]IRCCS - AOU di Bologna,Bologna,Italy,40138[322]Istituto Oncologico Veneto IRCCS,Padova,Italy,35128[323]Ospedale di Circolo e Fondazione Macchi Varese,Varese,Italy,21100[324]Aichi Cancer Center Hospital,Nagoya,Aichi,Japan,464-8681[325]National Cancer Center Hospital East,Kashiwa,Chiba,Japan,277-8577[326]National Hospital Organization Shikoku Cancer Center,Matsuyama,Ehime,Japan,791-0280[327]Hokkaido University Hospital,Sapporo,Hokkaido,Japan,060-8648[328]Himeji Medical Center,Himeji,Hyogo,Japan,670-8520[329]Kanazawa University Hospital,Kanazawa,Ishikawa,Japan,920-8641[330]Kanagawa Cardiovascular and Respiratory Center,Yokohama,Kanagawa,Japan,236-0051[331]Kanagawa cancer center,Yokohama,Kanagawa,Japan,2418515[332]Miyagi Cancer Center,Natori,Miyagi,Japan,981-1293[333]Niigata Cancer Center Hospital,Niigata-shi,Niigata,Japan,951-8566[334]Kansai Medical University Hospital,Hirakata,Osaka,Japan,573-1191[335]Kindai University Hospital- Osakasayama Campus,Osakasayama,Osaka,Japan,589-8511[336]National Hospital Organization Kinki-chuo Chest Medical Center,Sakai,Osaka,Japan,591-8555[337]Saitama Medical University International Medical Center,Hidaka,Saitama,Japan,350-1298[338]Tominaga Hospital,Nagaizumi-cho,Sunto-gun,Shizuoka,Japan,411-8777[339]Juntendo University Hospital,Bunkyo-ku,Tokyo,Japan,113-8431[340]Tokyo Metropolitan Komagome Hospital,Bunkyō-Ku,Tokyo,Japan,113-8677[341]Japanese Foundation for Cancer Research,Koto,Tokyo,Japan,135-8550[342]Tottori University Hospital,Yonago,Tottori,Japan,683-8504[343]National Hospital Organization Yamaguchi Ube Medical Center,Ube,Yamaguchi,Japan,755-0241[344]National Hospital Organization Kyushu Cancer Center,Fukuoka,Japan,811-1395[345]Kyushu University Hospital,Fukuoka,Japan,812-8582[346]University Hospital,Kyoto Prefectural University of Medicine,Kyoto,Japan,602-8566[347]Okayama University Hospital,Okayama,Japan,700-8558[348]Wakayama Medical University Hospital,Wakayama,Japan,641-8510[349]Chonnam National University Hwasun Hospital,Hwasun,Jeonranamdo,Korea, Republic of,58128[350]National Cancer Center,Goyang-si,Kyǒnggi-do,Korea, Republic of,10408[351]The Catholic University Of Korea St. Vincent's Hospital,Suwon-si,Kyǒnggi-do,Korea, Republic of,16247[352]Pusan National University Yangsan Hospital,Yangsan,Kyǒngsangnam-do,Korea, Republic of,KS011[353]Samsung Medical Center,Seoul,Seoul-teukbyeolsi,Korea, Republic of,06351[354]Kyungpook National University Chilgok Hospital,Daegu,Taegu-Kwangyǒkshi,Korea, Republic of,41404[355]Keimyung University Dongsan Hospital,Daegu,Taegu-Kwangyǒkshi,Korea, Republic of,42601[356]Health Pharma Professional Research S.A. de C.V:,Ciudad de México,Distrito Federal,Mexico,03100[357]Centro Onco-Hematológico Roma (COHR),Mexico City,Distrito Federal,Mexico,06700[358]Higiea Oncologia,Mexico City,Distrito Federal,Mexico,11819[359]Preparaciones Oncológicas S.C.,León,Guanajuato,Mexico,37178[360]CIO - Centro de Inmuno-Oncología de Occidente,Guadalajara,Jalisco,Mexico,44630[361]PanAmerican Clinical Research - Guadalajara,Guadalajara,Jalisco,Mexico,44670[362]Actualidad Basada en la Investigación del Cáncer,Guadalajara,Jalisco,Mexico,44680[363]Renati Innovation,Guadalajara,Jalisco,Mexico,44680[364]Dr. Jose Eleuterio Gonzalez,Monterrey,Nuevo León,Mexico,64460[365]Avix Investigación Clinica, S.C.,Monterrey,Nuevo León,Mexico,64710[366]Oncare - Unidad Valle,San Pedro Garza García,Nuevo León,Mexico,66220[367]Health Pharma Querétaro,Juriquilla,Querétaro,Mexico,76230[368]Centro de Investigacion Clinica de Oaxaca,Oaxaca,Mexico,68020[369]Clinica Integral Internacional de Oncología,Puebla,Mexico,72530[370]Arké SMO S.A de C.V,Veracruz,Mexico,91910[371]Medische Centrum Leeuwarden,Leeuwarden,Fryslân,Netherlands,8934 AD[372]Jeroen Bosch ziekenhuis,Den Bosch,Noord-Brabant,Netherlands,5223 GZ[373]ETZ Elisabeth,Tilburg,Noord-Brabant,Netherlands,5022 GC[374]Medisch Spectrum Twente,Enschede,Overijssel,Netherlands,7512 KZ[375]Leids Universitair Medisch Centrum,Leiden,Zuid-Holland,Netherlands,2333 ZA[376]Erasmus Medisch Centrum,Rotterdam,Zuid-Holland,Netherlands,3015 GD[377]St. Antonius Ziekenhuis, locatie Utrecht,Utrecht,Netherlands,3543 AZ[378]Akershus Universitetssykehus,Lørenskog,Akershus,Norway,1478[379]Drammen Sykehus, Vestre Viken HF,Drammen,Buskerud,Norway,3004[380]Haukeland Universitetssjukehus,Bergen,Hordaland,Norway,5021[381]Sykehuset Innlandet HF Gjøvik,Gjøvik,Oppland,Norway,2819[382]Stavanger Universitetssykehus,Stavanger,Rogaland,Norway,4011[383]St. Olavs Hospital,Trondheim,Sør-Trøndelag,Norway,7030[384]Oslo Universitetssykehus Ullevål,Oslo,Norway,0450[385]MICS Centrum Medyczne Torun,Torun,Kujawsko-pomorskie,Poland,87-100[386]Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej,Kielce,Świętokrzyskie,Poland,25-734[387]Champalimaud Foundation,Lisbon,Lisboa,Portugal,1400-038
研究目的:
The purpose of this study is to assess if adding LY3537982 in combination with standard of care anti-cancer drugs is more effective than standard of care in participants with untreated advanced NSCLC. NSCLC must have a change in a gene called KRAS G12C. Study participation, including follow-up, could last up to 3 years, depending on how you and your lung cancer are doing.