研究单位：[1]Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital),Hangzhou,Zhejiang,China,310000[2]First Affiliated Hospital of Wenzhou Medical University[3]Liaoning Tumor Hospital & Institute[4]RenJi Hospital[5]Fujian Cancer Hospital[6]Sun Yat-sen University[7]The Second Affiliated Hospital of Harbin Medical University[8]Sichuan Cancer Hospital and Research Institute[9]Zhejiang Provincial Tongde Hospital[10]Yuhang District Hospital of Traditional Chinese Medicine[11]The First People's Hospital of Yuhang District[12]The First Affiliated Hospital of Anhui University of Chinese Medicine[13]BGI-Shenzhen[14]Shangyu People's Hospital[15]Xianju People's Hospital[16]Shanghai Zhongshan Hospital
This is a prospective, multi-center, observational cohort study and seeks to enroll 20000 patients with one malignant tumor of digestive tract or healthy individual. This study collected tongue coating samples non-invasively and analyzed the tongue coating metaproteomics, metagenomics and metabolomics profiles of patients with gastrointestinal malignancies. The performance characteristics(sensitivity and specificity) of tongue coating morphology, metaproteomics, metagenomics and metabolomics tests for detection of gastrointestinal malignancies are evaluated in comparison to pathology.
