研究单位:[1]Daiichi Sankyo, Inc.[2]AstraZeneca[3]Merck Sharp & Dohme LLC[4]Ironwood Cancer and Research Centers,Chandler,Arizona,United States,85224[5]Compassionate Cancer Care Medical Group,Riverside,California,United States,92501[6]UCHealth Memorial Hospital,Colorado Springs,Colorado,United States,80909[7]Cancer Specialist of North Florida,Jacksonville,Florida,United States,32256[8]American Oncology Partners of Maryland,Bethesda,Maryland,United States,20817[9]Astera Cancer Care,East Brunswick,New Jersey,United States,08816[10]Regional Cancer Care Associates LLC,Hackensack,New Jersey,United States,07601[11]North Shore Hematology Oncology Associates,Patchogue,New York,United States,11772[12]North Shore Hematology Oncology Associates DBA NY Cancer and Blood Specialists,Port Jefferson Station,New York,United States,11776[13]Utah Cancer Specialists IHO Corp,Salt Lake City,Utah,United States,84106[14]Providence Regional Cancer System,Lacey,Washington,United States,98503[15]CRSA/ St Andrews Hospital,Adelaide,Australia,5000[16]PSEHOG (Peninsula and South Eastern Haematology and Oncology Group),Frankston,Australia,3199[17]Southern Medical Day Care Centre,Wollongong,Australia,2500[18]Princess Alexandra Hospital,Woolloongabba,Australia,QLD 4102[19]CHU de Quebec -Universite Laval Hopital de L'Enfant-Jesus,Quebec City,Canada,G1J 1Z4[20]University of Electronic Science Technology of China UESTC - Sichuan Cancer Hospital Institute SIC,Chengdu,China,610041[21]Jiamusi Cancer Hospital,Jiamusi,China,154007[22]Zhongda Hospital, Southeast University,Nanjing,China,210009[23]Shanghai Chest Hospital,Shanghai,China,200052[24]Union Hospital of Tongji Medical College Huazhong University of Science and Technology,Wuhan,China,430022[25]Xiangyang Central Hospital,Xianyang,China,441021[26]The First Affiliated Hosptial of Xinjiang Medical University,Ürümqi,China,830000[27]Prince of Wales Hospital / The Chinese University of Hong Kong,Hong Kong,Hong Kong,99999[28]Kurume University Hospital,Azuma,Japan[29]Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital,Bunkyō-Ku,Japan,113-0021[30]Kyushu University Hospital,Fukuoka,Japan,812-0054[31]Matsusaka Municipal Hospital,Hataji,Japan[32]Kansai Medical University Hospital,Hirakata,Japan,573-1191[33]Iwakuni Clinical Center,Iwakuni,Japan,740-8510[34]Kanazawa University Hospital,Kanazawa-shi,Japan,920-8641[35]Juntendo University Hospital,Kanemaru,Japan[36]The Cancer Institute Hospital of JFCR,Koto,Japan,135-0063[37]NHO Shikoku Cancer Center,Kozuki,Japan[38]Social Welfare Organization Saiseikai Imperial Gift Foundation, Inc. Saiseikai Kumamoto Hospital,Kumamoto,Japan,861-4193[39]University Hospital Kyoto Prefectual University of Medicine,Kyoto,Japan,602-8566[40]Matsusaka City Hospital,Matsusaka,Japan,515-8544[41]Niigata Cancer Center Hospital,Niigata,Japan,951-8566[42]Kyushu Cancer Center,Okamato,Japan[43]Teine Keijinkai Hospital,Sapporo-shi,Japan,006-0811[44]Sendai Kousei Hospital,Sendai,Japan,980-0873[45]Dokkyo Medical University Hospital,Shimotsuga-gun,Japan,321-0293[46]Osaka Toneyama Medical Center,Toyonaka-shi,Japan,560-8552[47]Yamaguchi-Ube Medical Center,Ube-shi,Japan,755-0241[48]Kanagawa Cancer Center,Yokohama,Japan,241-8515[49]Chungbuk National University Hospital,Cheongjusi,Korea, Republic of,28644[50]Kyungpook National University Chilgok Hospital,Daegu,Korea, Republic of,41404[51]Samsung Medical Center,Gangnam-Gu,Korea, Republic of,6351[52]National Cancer Center,Goyang-si,Korea, Republic of,10408[53]Seoul National University Bundang Hospital,Seongnam-si,Korea, Republic of,13620[54]Asan Medical Center,Seoul,Korea, Republic of,05505[55]China Medical University Hospital,Hsia,Taiwan[56]National Taiwan University Hospital,Taipei,Taiwan,10055[57]Siriraj Hospital,Bangkok,Thailand,10700[58]Chiang Mai University CMU - Maharaj Nakhon Chiang Mai Hospital Nakorn Ch
This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab in combination with pemetrexed and platinum chemotherapy in participants with no prior therapy for advanced or metastatic non-squamous non-small cell lung cancer (NSCLC).