研究单位:[1]Eli Lilly and Company[2]USO - Southern Cancer Center,Daphne,Alabama,United States,36526[3]CCI - Clearview Cancer Institute,Huntsville,Alabama,United States,35805[4]Infirmary Cancer Care,Mobile,Alabama,United States,36607[5]Banner MD Anderson Cancer Center,Gilbert,Arizona,United States,85234[6]Arizona Oncology Associates, P.C. - HOPE,Glendale,Arizona,United States,85308[7]St. Joseph's Hospital and Medical Center,Phoenix,Arizona,United States,85004[8]Mayo Clinic in Arizona - Phoenix,Phoenix,Arizona,United States,85054[9]USO - Arizona Oncology Associates - HOPE,Tucson,Arizona,United States,85711[10]The University of Arizona Cancer Center - North Campus,Tucson,Arizona,United States,85719[11]St. Bernards Medical Center,Jonesboro,Arkansas,United States,72401[12]Highlands Oncology Group,Springdale,Arkansas,United States,72762[13]CBCC Global Research, Inc.,Bakersfield,California,United States,93309[14]Women''s Cancer Research Network - COGI,Fresno,California,United States,93710[15]Scripps Green Hospital,La Jolla,California,United States,92037[16]Loma Linda University Cancer Center,Loma Linda,California,United States,92350-1700[17]Cancer and Blood Specialty Clinic,Los Alamitos,California,United States,90720[18]TRIO-US (Translational Research in Oncology-US),Los Angeles,California,United States,90024[19]Mercy UC Davis Cancer Center,Merced,California,United States,95340[20]Pacific Cancer Care,Monterey,California,United States,93940[21]Cancer Center El Camino Hospital,Mountain View,California,United States,94040[22]St. Joseph Hospital,Orange,California,United States,92868[23]University of California, Irvine (UCI) Health - UC Irvine Medical Center,Orange,California,United States,92868[24]University of California Davis (UC Davis) Comprehensive Cancer Center,Sacramento,California,United States,95817[25]Scripps MD Anderson - Prebys Cancer Center,San Diego,California,United States,92103[26]Kaiser Permanente San Diego Mission Road,San Diego,California,United States,92108[27]St. Mary''s Medical Center,San Francisco,California,United States,94117[28]UCSF Medical Center at Mission Bay,San Francisco,California,United States,94158[29]Torrance Memorial Physician Network / Cancer Care,Torrance,California,United States,90505[30]Anschutz Cancer Pavilion,Aurora,Colorado,United States,80045[31]UCHealth Memorial Hospital,Colorado Springs,Colorado,United States,80909[32]University of Colorado Health - Harmony,Fort Collins,Colorado,United States,80528[33]Banner MD Anderson Cancer Center at North Colorado Medical Center,Greeley,Colorado,United States,80631[34]USO - Rocky Mountain Cancer Centers,Lakewood,Colorado,United States,80228[35]Banner MD Anderson Cancer Center at McKee Medical Center,Loveland,Colorado,United States,80538[36]Yale-New Haven Hospital,New Haven,Connecticut,United States,06510[37]AdventHealth Altamonte Springs,Altamonte Springs,Florida,United States,32701[38]Holy Cross Hospital,Fort Lauderdale,Florida,United States,33308[39]Memorial Regional Hospital,Hollywood,Florida,United States,33021[40]Millennium Oncology Research Clinic,Hollywood,Florida,United States,33024[41]Mayo Clinic in Florida,Jacksonville,Florida,United States,32224[42]USO - Cancer Care Centers of Brevard,Palm Bay,Florida,United States,32901[43]USO - Woodlands Medical Specialists,Pensacola,Florida,United States,32503[44]Winship Cancer Institute, Emory University,Atlanta,Georgia,United States,30322[45]Northside Hospital,Atlanta,Georgia,United States,30342[46]Augusta University,Augusta,Georgia,United States,30912[47]Summit Cancer Care DBA Candler Medical Oncology Practice,Savannah,Georgia,United States,31405[48]Kaiser Permanente Moanalua Medical Center,Honolulu,Hawaii,United States,96819[49]Kapiolani Medical Center for Women and Children,Honolulu,Hawaii,United States,96826[50]Saint Alphonsus Regional Medical Center,Boise,Idaho,United States,83706[51]Rush University Medical Center,Chicago,Illinois,United States,60607[52]University of Illinois at Chicago,Chicago,Illinois,United States,60612[53]Illinois Cancer Care,Peoria,Illinois,United States,61615[54]Simmons Cancer Institute at SIU,Springfield,Illinois,United States,62702[55]The University of Kansas Cancer Center - Westwood,Westwood,Kansas,United States,66205[56]Hematology Oncology Clinic,Baton Rouge,Louisiana,United States,70809[57]Pontchartrain Cancer Center,Hammond,Louisiana,United States,70403[58]Central Maine Medical Center,Lewiston,Maine,United States,04240[59]York Hospital,York,Maine,United States,03909[60]USO - Maryland Oncology Hematology,Annapolis,Maryland,United States,21401[61]Walter Reed National Military Medical Center,Bethesda,Maryland,United States,20889[62]Massachusetts General Hospital,Boston,Massachusetts,United States,02114[63]Dana-Farber Cancer Institute,Boston,Massachusetts,United States,02215[64]Southcoast Centers for Cancer Care,Fairhaven,Massachusetts,United States,02719[65]University of Massachusetts Medical School,Worcester,Massachusetts,United States,01655[66]M Health Fairview Cancer Clinic -Edina,Edina,Minnesota,United States,55435[67]USO - Minnesota Oncology Hematology,Minneapolis,Minnesota,United States,55404[68]Allina Health Cancer Institute,Minneapolis,Minnesota,United States,55407[69]Mayo Clinic in Rochester, Minnesota,Rochester,Minnesota,United States,55905[70]University of Missouri Hospital,Columbia,Missouri,United States,65212[71]Washington University School of Medicine,Saint Louis,Missouri,United States,63110[72]Nebraska Methodist Hospital,Omaha,Nebraska,United States,68114[73]Dartmouth-Hitchcock Medical Center,Lebanon,New Hampshire,United States,03756[74]Astera Cancer Care,East Brunswick,New Jersey,United States,08816[75]Regional Cancer Care Associates,Freehold,New Jersey,United States,07728[76]Regional Cancer Care Associates - Howell,Howell,New Jersey,United States,07731[77]Regional Cancer Care Associates,Little Silver,New Jersey,United States,07739[78]Rutgers Cancer Institute of New Jersey,New Brunswick,New Jersey,United States,08901[79]Capital Health Medical Center - Hopewell,Pennington,New Jersey,United States,08534[80]University of New Mexico Comprehensive Cancer Center,Albuquerque,New Mexico,United States,87131[81]Memorial Medical Center,Las Cruces,New Mexico,United States,88011[82]USO - New York Oncology Hematology,Albany,New York,United States,12206[83]Maimonides Cancer Center,Brooklyn,New York,United States,11220[84]USO - Broome Oncology LLC,Johnson City,New York,United States,13790[85]Perlmutter Cancer Center at NYU Langone Hospital - Long Island,Mineola,New York,United States,11501[86]Laura and Isaac Perlmutter Cancer Center,New York,New York,United States,10016[87]NYC Health + Hospitals / Bellevue,New York,New York,United States,10016[88]Columbia University Medical Center,New York,New York,United States,10032[89]Memorial Sloan Kettering Cancer Center,New York,New York,United States,10065[90]University of Rochester,Rochester,New York,United States,14642[91]SUNY Upstate Medical University,Syracuse,New York,United States,13210[92]Messino Cancer Center,Asheville,North Carolina,United States,28806[93]Aultman Hospital - Timken Family Cancer Center,Canton,Ohio,United States,44710[94]The Christ Hospital Cancer Center,Cincinnati,Ohio,United States,45219[95]Mark H Zangmeister Center,Columbus,Ohio,United States,43219[96]Mercy Health - St. Vincent Medical Center,Toledo,Ohio,United States,43608[97]St. Elizabeth Youngstown Hospital,Youngstown,Ohio,United States,44501[98]Good Samaritan Regional Medical Center,Corvallis,Oregon,United States,97330[99]USO - Oncology Associates of Oregon,Eugene,Oregon,United States,97401[100]Oregon Health and Science University,Portland,Oregon,United States,97239[101]USO - Compass Oncology,Tigard,Oregon,United States,97223[102]St. Luke''s University Health Network,Bethlehem,Pennsylvania,United States,18015[103]Penn State Univ. Milton S. Hershey Medical Center,Hershey,Pennsylvania,United States,17033[104]USO - Alliance Cancer Specialists, PC,Horsham,Pennsylvania,United States,19044[105]Thomas Jefferson University - Clinical Research Institute,Philadelphia,Pennsylvania,United States,19107[106]Thomas Jefferson University, Aria Jefferson Health,Philadelphia,Pennsylvania,United States,19114[107]Asplundh Cancer Pavilion,Willow Grove,Pennsylvania,United States,19090[108]Rhode Island Hospital,Providence,Rhode Island,United States,02903[109]St Francis Cancer Center,Greenville,South Carolina,United States,29607[110]University of Tennessee Medical Center,Knoxville,Tennessee,United States,37920[111]Sarah Cannon Research Institute SCRI,Nashville,Tennessee,United States,37203[112]USO - Texas Oncology, P. A.,Austin,Texas,United States,78731[113]USO - Texas Oncology,Beaumont,Texas,United States,77702[114]Texas Oncology - Medical City Dallas,Dallas,Texas,United States,75230[115]USO - Texas Oncology, P. A.,Dallas,Texas,United States,75231[116]USO - Texas Oncology,Dallas,Texas,United States,75246[117]USO - Texas Oncology, P. A.,Denison,Texas,United States,75020[118]USO - Texas Oncology, P. A.,Denton,Texas,United States,76201[119]William Beaumont Army Medical Center,El Paso,Texas,United States,79918[120]USO - Texas Oncology, P. A.,Flower Mound,Texas,United States,75028[121]Brooke Army Medical Center,Fort Sam Houston,Texas,United States,78234[122]The Center for Cancer and Blood Disorders,Fort Worth,Texas,United States,76104[123]USO - Texas Oncology,Fort Worth,Texas,United States,76104[124]USO - Texas Oncology,Fredericksburg,Texas,United States,78624[125]Texas Oncology - McAllen,McAllen,Texas,United States,78503[126]USO - Texas Oncology,McKinney,Texas,United States,75071[127]USO - Texas Oncology,Plano,Texas,United States,75075[128]Mays Cancer Center,San Antonio,Texas,United States,78229[129]Oncology Consultants,Sugar Land,Texas,United States,77479[130]Baylor Scott & White Medical Center - Temple,Temple,Texas,United States,76508[131]US Oncology,The Woodlands,Texas,United States,77380[132]USO - Texas Oncology,The Woodlands,Texas,United States,77380[133]Texas Oncology - Tyler,Tyler,Texas,United States,75702[134]USO - Texas Oncology,Webster,Texas,United States,77598[135]The University of Vermont Medical Center Inc.,Burlington,Vermont,United States,05405[136]University of Virginia Health System,Charlottesville,Virginia,United States,22903[137]Inova Schar Cancer Institute,Fairfax,Virginia,United States,22031[138]Fort Belvoir Community Hospital,Fort Belvoir,Virginia,United States,22060[139]Bon Secours St. Francis Medical Center,Midlothian,Virginia,United States,23114[140]USO - Virginia Oncology Associates,Norfolk,Virginia,United States,23502[141]USO - Virginia Cancer Specialists,Reston,Virginia,United States,20190[142]Oncology and Hematology Associates of Southwest Virginia Inc,Roanoke,Virginia,United States,24014[143]Centro de Oncología e Investigación de Buenos Aires,Berazategui,Buenos Aires,Argentina,B1884BBF[144]Instituto Alexander Fleming,Ciudad Autónoma de Buenos Aire,Buenos Aires,Argentina,C1426ANZ[145]Instituto de Investigaciones Clínicas Mar del Plata,Mar del Plata,Buenos Aires,Argentina,7600[146]Go Centro Medico San Nicolás,San Nicolas,Buenos Aires,Argentina,2900[147]Investigaciones Clinicas Moleculares (ICM),Buenos Aires,Ciudad Aut,Argentina,1425[148]CIPREC,Caba,Ciudad Aut,Argentina,C1061AAS[149]Clinica Adventista Belgrano,Caba,Ciudad Aut,Argentina,C1430EGF[150]Mautalen Salud e Investigación,Buenos Aires,Ciudad Autónoma De Buenos Aire,Argentina,C1128AAF[151]Fundación Cenit Para La Investigación En Neurociencias,Caba,Ciudad Autónoma De Buenos Aire,Argentina,1125[152]Centro Medico Privado CEMAIC,Capital,Córdoba,Argentina,X5008HHW[153]Instituto Médico Río Cuarto,Río Cuarto,Córdoba,Argentina,X5800AEV[154]Clinica Viedma S. A,Viedma,Río Negro,Argentina,R8500ACE[155]Fundacion Estudios Clinicos,Rosario,Santa Fe,Argentina,S2000DEJ[156]Centro Medico San Roque,San Miguel de Tucumán,Tucumán,Argentina,T4000IAK[157]Centro Oncologico Korben,Buenos Aires,Argentina,1426[158]Fundación Respirar,Buenos Aires,Argentina,C1426ABP[159]Fundación CORI para la Investigación y Prevención del Cáncer,La Rioja,Argentina,F5300COE[160]Fundacion Scherbovsky,Mendoza,Argentina,5500[161]Centro Polivalente de Asistencia e Investigacion Clinica - CER San Juan,San Juan,Argentina,5400[162]Instituto San Marcos,San Juan,Argentina,5400[163]Coffs Harbour Health Campus,Coffs Harbour,New South Wales,Australia,2450[164]St Vincent''s Hospital,Darlinghurst,New South Wales,Australia,2010[165]Gosford Hospital,Gosford,New South Wales,Australia,2250[166]Liverpool Hospital,Liverpool,New South Wales,Australia,2170[167]Lake Macquarie Private Hospital,Newcastle,New South Wales,Australia,2290[168]Mater Hospital Sydney,Sydney,New South Wales,Australia,2060[169]The Townsville Hospital,Townsville,Queensland,Australia,4814[170]Hervey Bay Hospital,Urraween,Queensland,Australia,4655[171]Launceston General Hospital,Launceston,Tasmania,Australia,7250[172]Ballarat Oncology and Haematology,Ballarat Central,Victoria,Australia,3350[173]Box Hill Hospital,Box Hill,Victoria,Australia,3128[174]Monash Health,Clayton,Victoria,Australia,3168[175]Barwon Health,Geelong,Victoria,Australia,3220[176]St Vincent''s Hospital,Melbourne,Victoria,Australia,3065[177]Northern Hospital,Melbourne,Victoria,Australia,3076[178]Maroondah Hospital,Melbourne,Victoria,Australia,3135[179]Goulburn Valley Health,Shepparton,Victoria,Australia,3630[180]Breast Cancer Research Centre-WA,Nedlands,Western Australia,Australia,6009[181]St. John of God Subiaco Hospital,Subiaco,Western Australia,Australia,6008[182]Medizinische Universität Graz,Graz,Steiermark,Austria,8036[183]Private Practice - Dr. Hubalek,Schwaz,Tirol,Austria,6130[184]Franziskus Spital GmbH,Vienna,Wien,Austria,1050[185]Medizinische Universität Wien,Vienna,Wien,Austria,1090[186]Krankenhaus Hietzing,Vienna,Wien,Austria,1130[187]Uniklinikum Salzburg,Salzburg,Austria,5020[188]Medizinische Universität Wien,Wien,Austria,1090[189]Clinique Saint Pierre,Ottignies,Brabant Wallon,Belgium,1340[190]Institut Jules Bordet,Anderlecht,Bruxelles-Capitale, Région De,Belgium,1070[191]CHIREC - site delta,Auderghem,Bruxelles-Capitale, Région De,Belgium,1160[192]CHU Saint-Pierre,Brussels,Bruxelles-Capitale, Région De,Belgium,1000[193]Cliniques universitaires Saint-Luc,Brussels,Bruxelles-Capitale, Région De,Belgium,1200[194]Grand Hôpital de Charleroi - Saint-Joseph,Charleroi,Hainaut,Belgium,6000[195]Groupe Jolimont,La Louvière,Hainaut,Belgium,7100[196]CHU de Charleroi - Hopital Civil Marie Curie,Lodelinsart,Hainaut,Belgium,6042[197]Jessa Ziekenhuis,Hasselt,Limburg,Belgium,3500[198]CHR Verviers - La Tourelle,Verviers,Liège,Belgium,4800[199]VITAZ,Sint-Niklaas,Oost-Vlaanderen,Belgium,B-9100[200]UZ Leuven,Leuven,Vlaams-Brabant,Belgium,3000[201]Jan Yperman Ziekenhuis,Ieper,West-Vlaanderen,Belgium,8900[202]AZ Groeninge Campus Kennedylaan,Kortrijk,West-Vlaanderen,Belgium,8500[203]Centre Hospitalier Universitaire Sart Tilman,Liège,Belgium,4000[204]CHU UCL Namur/Site Sainte Elisabeth,Namur,Belgium,5000[205]Nucleo de Oncologia da Bahia,Salvador,Bahia,Brazil,40170-110[206]Centro de Pesquisa Clínica do Instituto do Câncer do Ceará,Fortaleza,Ceará,Brazil,60430235[207]CEDOES,Vitória,Espírito Santo,Brazil,29055450[208]Hospital Araújo Jorge,Goiânia,Goiás,Brazil,74605070[209]Oncocentro de Minas Gerais,Belo Horizonte,Minas Gerais,Brazil,30180-060[210]Centro Integrado de Oncologia de Curitiba,Curitiba,Paraná,Brazil,80810050[211]Hospital de Cancer de Londrina,Londrina,Paraná,Brazil,86015-520[212]CTO - Centro de Tratamento Oncológico,Belem,Pará,Brazil,66063-495[213]Multihemo,Recife,Pernambuco,Brazil,50070-170[214]ONCOSITE - Centro de Pesquisa Clinica em Oncologia,Ijui,Rio Grande Do Sul,Brazil,98700-000[215]Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa,Porto Alegre,Rio Grande Do Sul,Brazil,90110-270[216]Hospital Moinhos de Vento,Porto Alegre,Rio Grande,Brazil,90035-001[217]Hospital de Amor Amazônia,Porto Velho,Rondônia,Brazil,76834-899[218]Fundação Pio XII - Hospital de Câncer de Barretos,Barretos,São Paulo,Brazil,14784400[219]Hospital de Clínicas de Ribeirão Preto,Ribeirão Preto,São Paulo,Brazil,14051-140[220]Faculdade de Medicina do ABC,Santo André,São Paulo,Brazil,09060-650[221]Hospital Sírio Libanês,Sao Paulo,São Paulo,Brazil,01308-060[222]BP - A Beneficencia Portuguesa de São Paulo,Sao Paulo,São Paulo,Brazil,01321-001[223]A. C. Camargo Cancer Center,Sao Paulo,São Paulo,Brazil,01509-010[224]Instituto D''Or de Pesquisa e Ensino (IDOR),Sao Paulo,São Paulo,Brazil,04543-000[225]Hospital Santa Paula,Sao Paulo,São Paulo,Brazil,04556-100[226]Hospital de Base de São José do Rio Preto,São José do Rio Preto,São Paulo,Brazil,15091-000[227]Hospital Sirio Libanes,Brasilia,Brazil,70200-730[228]Hospital São Lucas da PUCRS,Porto Alegre,Brazil,90610[229]Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA,Rio de Janeiro,Brazil,20560121[230]Hospital São Lucas Copacabana,Rio de Janeiro,Brazil,22061-080[231]Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA,Rio de Janeiro,Brazil,22250-905[232]Instituto de Educação, Pesquisa e Gestão em Saúde,Rio de Janeiro,Brazil,22793-080[233]IPITEC,São Paulo,Brazil,01223-001[234]NotreDame Intermedica Saude S.A,São Paulo,Brazil,01229-010[235]Instituto de Ensino e Pesquisa São Lucas,São Paulo,Brazil,01236030[236]Icesp - Instituto Do Câncer Do Estado de São Paulo,São Paulo,Brazil,01246-000[237]Clínica de Pesquisas e Centro de Estudos em Oncologia Ginecológica e Mamária Ltda,São Paulo,Brazil,01317-000[238]Hospital Alemao Oswaldo Cruz,São Paulo,Brazil,01327-001[239]Núcleo de Pesquisa Clínica da Rede São Camilo,São Paulo,Brazil,04014-002[240]Instituto de Assistência Médica ao Servidor Público Estadual - IAMSPE/HSPE-FMO Conhecer Centro de Oncologia para Ensaios Clínicos e Estudos,São Paulo,Brazil,04039-901[241]Tom Baker Cancer Center,Calgary,Alberta,Canada,T2N 4N2[242]BC Cancer Surrey,Surrey,British Columbia,Canada,V3V 1Z2[243]Victoria Hospital & Children''s Hospital - London Health Sciences Centre,London,Ontario,Canada,N6A 5W9[244]Humber River Hospital,Toronto,Ontario,Canada,M3M 0B2[245]Sunnybrook Research Institute - Odette Cancer Centre,Toronto,Ontario,Canada,M4N 3M5[246]Jewish General Hospital,Montreal,Quebec,Canada,H3T 1E2[247]Centre intégré universitaire de santé et de services sociaux du Nord-de-l''Île-de-Montréal (CIUSSS NÎM) - Hôpital du Sacré-Coeur de Montréal,Montreal,Quebec,Canada,H4J 1C5[248]Centre Hospitalier de l''Université de Montréal,Montréal,Quebec,Canada,H2X 3E4[249]Hopital Du Saint-Sacrement,Quebec City,Quebec,Canada,G1S 4L8[250]The First Afflilated Hospital of Bengbu Medical College,Bengbu,Anhui,China,233004[251]Beijing Hospital,Beijing,Beijing,China,100005[252]Cancer Hospital Chinese Academy of Medical Science,Beijing,Beijing,China,100021[253]Peking University People''s Hospital,Beijing,Beijing,China,100034[254]Beijing Friendship Hospital Affiliate of Capital University,Beijing,Beijing,China,100050[255]Sichuan Cancer hospital,Chengdu,Sichuan,China,610042[256]Fujian Medical University Union Hospital-1 Bingfanglou,Fuzhou Fujian,Fujian,China,350001[257]Fuzhou General hospital of Nanjing Military Command,Fuzhou,Fujian,China,350025[258]Sun Yat-Sen University Cancer Centre,Guangzhou,Guangdong,China,510060[259]Guangdong Maternity and Child Health Care Hospital,Guangzhou,Guangdong,China,511400[260]Jiangmen Center Hospital,Jiangmen,Guangdong,China[261]ShenZhen People''s Hospital,Shenzhen,Guangdong,China,518020[262]Hainan General Hospital,Haikou,Hainan,China,570311[263]Affiliated Hospital of Hebei University,Baoding,Hebei,China,071066[264]Hebei General Hospital,ShiJiazhuang,Hebei,China,050051[265]The First Affiliated Hospital of Henan University of Science &Technology,Luoyang,Henan,China,471003[266]People''s Hospital of Henan Province,Zhengzhou,Henan,China,450003[267]Wuhan Union Hospital,Wuhan,Hubei,China,430022[268]Renmin Hospital of Wuhan University,Wuhan,Hubei,China,430060[269]Hubei Cancer Hospital,Wuhan,Hubei,China,430079[270]Xiangyang Central Hospital,Xiangyang,Hubei,China,441021[271]The First People''s Hospital of Changde City,Changde,Hunan,China,415003[272]Hunan Provincial People''s Hospital,ChangSha,Hunan,China,410005[273]Xiangya Hospital Central South University,Changsha,Hunan,China,410008[274]Hunan Cancer Hospital,Changsha,Hunan,China,421000[275]The First People''s Hospital of Yueyang,Yueyang,Hunan,China,414000[276]Jiangsu provincial people''s hospital,Nanjing,Jiangsu,China,210029[277]The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215006[278]The Third Hospital of Nanchang,Nanchang,Jiangxi,China,330009[279]The First Hospital of Jilin University,Changchun,Jilin,China,130021[280]The Second Hospital of Jilin University,Changchun,Jilin,China[281]Dalian University - The Affiliated Zhongshan Hospital,Dalian,Liaoning,China,116001[282]The First Affiliated Hospital of Xi''an Jiaotong University,Xi''an,Shaanxi,China,710061[283]The First Affiliated Hospital of Xi''an Jiaotong University,Xi''an,Shaanxi,China,710061[284]Jining Medical University - Affiliated Hospital,Jining,Shandong,China,272100[285]Fudan University Shanghai Cancer Center,Shanghai,Shanghai,China,200032[286]Yuncheng Central Hospital - Eastern Hospital,Yuncheng Shi,Shanxi,China,044000[287]Sichuan Cancer hospital,Chengdu,Sichuan,China,610042[288]The Second People''s Hospital of Neijiang,Neijiang,Sichuan,China,641000[289]Tianjin Medical University Cancer Institute and Hospital,Tianjing,Tianjin,China,300060[290]Yunnan Province Cancer Hospital,Kunming,Yunnan,China,650106[291]The First People''s Hospital of Hangzhou,Hangzhou,Zhejiang,China,310000[292]Zhejiang Provincial People''s Hospital,Hangzhou,Zhejiang,China,310014[293]Ningbo First Hospital,Ningbo,Zhejiang,China,315010[294]The Affiliated People''s Hospital of Ningbo University,Ningbo,Zhejiang,China,315040[295]Shaoxing People''s Hospital,Shaoxing,Zhejiang,China,312000[296]Nemocnice Horovice,Horovice,Beroun,Czechia,268 31[297]Masarykuv onkologicky ustav,Brno,Brno-město,Czechia,656 53[298]Fakultni nemocnice Ostrava,Ostrava,Moravskoslezský Kraj,Czechia,708 52[299]Multiscan,Pardubice,Pardubický Kraj,Czechia,53203[300]Thomayerova nemocnice,Prague,Praha 4,Czechia,14059
研究目的:
The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy in participants with early breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have already taken endocrine therapy for two to five years and must have a higher-than-average risk for their cancer to return. Study participation could last up to 10 years.