研究单位：[1]Akeso[2]Fudan University[3]Cancer Hospital of The University of Chinese Academy of Sciences[4]Memorial Sloan Kettering Cancer Center[5]City of Hope,Duarte,California,United States,91010[6]University of Michigan,Ann Arbor,Michigan,United States,48109[7]Icahn School of Medicine at Mount Sinai,New York,New York,United States,10029[8]Memorial Sloan Kettering Cancer Center,New York,New York,United States,10065[9]Blacktown Hospital,Blacktown,New South Wales,Australia,2148[10]Chris O'Brien Lifehouse,Camperdown,New South Wales,Australia[11]St Vincent''s Public Hospital Sydney,Darlinghurst,New South Wales,Australia,2010[12]Genesis Care North Shore,St Leonards,New South Wales,Australia,2065[13]The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui,China,230022[14]Fujian Cancer Hospital,Fuzhou,Fujian,China,350014[15]The First Affiliated Hospital of Xiamen University,Xiamen,Fujian,China,361003[16]Dongguan People''s Hospital,Dongguan,Guangdong,China,523058[17]The First Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong,China,510080[18]Affiliated Cancer Hospital and Institute of Guangzhou Medical University,Guangzhou,Guangdong,China,510095[19]Sun Yat-sen Memorial Hospital, Sun Yat-sen University,Guangzhou,Guangdong,China,510120[20]The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong,China,510120[21]Zhujiang Hospital of Southern Medical University,Guangzhou,Guangdong,China,510260[22]Nanfang Hospital, Southern Medical University,Guangzhou,Guangdong,China,510515[23]The Sixth Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong,China,510655[24]The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou,Guangdong,China,510699[25]Guangzhou Panyu Central Hospital,Guangzhou,Guangdong,China,511400[26]Jiangmen Central Hospital,Jiangmen,Guangdong,China,529000[27]Cancer Hospital of Shantou University Medical College,Shantou,Guangdong,China,515041[28]Shenzhen People''s Hospital,Shenzhen,Guangdong,China,518020[29]Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong,China,524000[30]The Fifth Affiliated Hospital of Sun Yat-sen University,Zhuhai,Guangdong,China,519000[31]Affiliated Hospital of Guilin Medical University,Guilin,Guangxi,China,541001[32]The People''s Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi,China,530016[33]Guangxi Medical University Cancer Hospital,Nanning,Guangxi,China,530021[34]The First Affiliated Hospital of Guangxi Medical University,Nanning,Guangxi,China,530021[35]Guizhou Cancer Hospital,Guiyang,Guizhou,China,550000[36]The First Affiliated Hospital of Hainan Medical University,Haikou,Hainan,China,570102[37]Hainan General Hospital,Haikou,Hainan,China,570311[38]Hubei Cancer Hospital,Wuhan,Hubei,China,430079[39]The Second Xiangya Hospital of Central South University,Changsha,Hunan,China,410012[40]Hunan Cancer Hospital,Changsha,Hunan,China,410031[41]The First Affiliated Hospital of University of South China,Hengyang,Hunan,China,421001[42]The Second Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,China,330002[43]Jiangxi Cancer Hospital,Nanchang,Jiangxi,China,330029[44]Fudan University Shanghai Cancer Center,Shanghai,Shanghai,China,200032[45]Sichuan Cancer Hospital,Chengdu,Sichuan,China,610042[46]The Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan,China,646000[47]Yunnan Cancer Hospital,Kunming,Yunnan,China,650118[48]Zhejiang Cancer Hospital,Hangzhou,Zhejiang,China,310005[49]Taizhou Hospital of Zhejiang Province,Taizhou,Zhejiang,China,317099
研究目的：
This study is a randomized, double-blind, multi-center phase III clinical study to compare the efficacy and safety of penpulimab combined with chemotherapy and placebo combined with chemotherapy in the first-line treatment of recurrent or metastatic nasopharyngeal carcinoma.
