研究单位:[1]Xinqiao Hospital of Chongqing[2]GeneCast Biotechnology Co., Ltd.[3]Shanghai Pulmonary Hospital, Shanghai, China[4]Shanghai Chest Hospital[5]Wuhan University[6]Renmin Hospital of Wuhan University[7]Tongji Hospital[8]Southwest Hospital, China[9]Daping Hospital and the Research Institute of Surgery of the Third Military Medical University[10]People's Hospital of Chongqing[11]Sichuan Cancer Hospital and Research Institute[12]The Second Affiliated Hospital of Kunming Medical University[13]First Affiliated Hospital of Wenzhou Medical University[14]The Affiliated Hospital Of Southwest Medical University[15]Guizhou Provincial People's Hospital[16]The First Affiliated Hospital of Zhengzhou University[17]Shanxi Provincial Cancer Hospital[18]First Hospital of China Medical University[19]Fujian Provincial Hospital[20]Peking University Shenzhen Hospital[21]Affiliated Cancer Hospital of Shantou University Medical College[22]The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine[23]Second Affiliated Hospital of Army Medical University,Chongqing,Chongqing,China,400000
研究目的:
This multicenter prospective observational and exploratory study aims to develop and validate a novel multi-omics-based computational method for neoantigen prediction in non-small cell lung cancer (NSCLC), and discover biomarkers for evaluation of PD-1/PD-L1 inhibitor's efficacy in patients of advanced NSCLC.