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Multi-Omics Testing for Immunotherapy Efficacy Evaluation (MOTIVATION)

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多中心研究:
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研究单位: [1]Xinqiao Hospital of Chongqing [2]GeneCast Biotechnology Co., Ltd. [3]Shanghai Pulmonary Hospital, Shanghai, China [4]Shanghai Chest Hospital [5]Wuhan University [6]Renmin Hospital of Wuhan University [7]Tongji Hospital [8]Southwest Hospital, China [9]Daping Hospital and the Research Institute of Surgery of the Third Military Medical University [10]People's Hospital of Chongqing [11]Sichuan Cancer Hospital and Research Institute [12]The Second Affiliated Hospital of Kunming Medical University [13]First Affiliated Hospital of Wenzhou Medical University [14]The Affiliated Hospital Of Southwest Medical University [15]Guizhou Provincial People's Hospital [16]The First Affiliated Hospital of Zhengzhou University [17]Shanxi Provincial Cancer Hospital [18]First Hospital of China Medical University [19]Fujian Provincial Hospital [20]Peking University Shenzhen Hospital [21]Affiliated Cancer Hospital of Shantou University Medical College [22]The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine [23]Second Affiliated Hospital of Army Medical University,Chongqing,Chongqing,China,400000

研究目的:
This multicenter prospective observational and exploratory study aims to develop and validate a novel multi-omics-based computational method for neoantigen prediction in non-small cell lung cancer (NSCLC), and discover biomarkers for evaluation of PD-1/PD-L1 inhibitor's efficacy in patients of advanced NSCLC.

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