研究单位：[1]Johnson & Johnson Enterprise Innovation Inc.[2]Memorial Radiation Oncology Medical Group Laguna Hills,Laguna Hills,California,United States,92653[3]Hoag Memorial Hospital,Newport Beach,California,United States,92663[4]University of California San Francisco,San Francisco,California,United States,94158[5]Moffitt Cancer Center,Tampa,Florida,United States,33612[6]Christus St. Vincent Regional Cancer Center,Santa Fe,New Mexico,United States,87505[7]Herbert Irving Comprehensive Cancer Center Columbia University Medical Center,New York,New York,United States,10032[8]Richmond University Medical Center,Staten Island,New York,United States,10310[9]University of North Carolina at Chapel Hill,Chapel Hill,North Carolina,United States,27514[10]Stephenson Cancer Center,Oklahoma City,Oklahoma,United States,73104[11]Medizinische Universität Graz,Graz,Austria,8036[12]Ordensklinikum Linz GmbH Barmherzige Schwestern,Linz,Austria,4010[13]Medizinische Universitaet Wien,Wien,Austria,1090[14]Cliniques Universitaires Saint Luc,Brussels,Belgium,1200[15]Grand Hôpital de Charleroi - Site Saint-Joseph,Gilly,Belgium,6060[16]Universitair Ziekenhuis Leuven,Leuven,Belgium,3000[17]Fundacao Pio Xii - Hospital De Cancer De Barretos,Barretos,Brazil,14784[18]Nucleo de Ensino e Pesquisa do Instituto Mario Penna,Belo Horizonte,Brazil,30380 472[19]Centro Regional Integrado de Oncologia CRIO,Fortaleza,Brazil,60336 232[20]Hospital Amaral Carvalho,Jau,Brazil,17210120[21]Hospital Sao Lucas da PUCRS,Porto Alegre,Brazil,90610-000[22]Hospital Nossa Senhora da Conceicao,Porto Alegre,Brazil,91350-200[23]Grupo Oncoclinicas - Botafogo,Rio De Janeiro,Brazil,22250-905[24]Hospital Sirio Libanes Sao Paulo,Sao Paulo,Brazil,01308-050[25]Irmandade da Santa Casa de Misericordia de Porto Alegre,Sao Paulo,Brazil,90050-170[26]Hospital de Base de Sao Jose do Rio Preto,São José do Rio Preto,Brazil,15090-000[27]MHAT Uni Hospital,Panagyurishte,Bulgaria,4500[28]Specialized Hospital for Active Treatment in Oncology,Sofia,Bulgaria,1756[29]The Affiliated Hospital of Bengbu Medical College,Bengbu,China,233004[30]Xiangya Hospital Central South University,Changsha,China,410008[31]Hunan Cancer hospital,ChangSha,China,410013[32]Sichuan Cancer Hospital,Chengdu,China,610041[33]Dongguan People s Hospital,Dongguan,China,523109[34]Fujian Medical University Union Hospital,Fu Zhou Shi,China,350001[35]The First Affiliated Hospital of Fujian Medical University,Fuzhou,China,350005[36]Fujian Medical University Fujian Provincial Cancer Hospital,Fuzhou,China,350014[37]The First Affiliated Hospital of Guangdong Pharmaceutical University,Guangzhou,China,510080[38]Guangzhou Medical University Affiliated Oncology Hospital,Guangzhou,China,510095[39]Guangzhou First Municipal People''s Hospital,Guangzhou,China,510180
This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy and safety of JNJ-90301900 (NBTXR3) / radiation therapy (RT)±cetuximab versus RT±cetuximab in treatment-naïve, platinum-ineligible, elderly participants with locally advanced head and neck squamous cell carcinoma (LA-HNSCC).
