A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)
研究单位：[1]Hoffmann-La Roche[2]Arizona Clinical Research Center, Inc,Tucson,Arizona,United States,85715[3]Genesis Cancer and Blood Institute,Hot Springs,Arkansas,United States,71913[4]Stanford University,Palo Alto,California,United States,94305[5]Banner MD Anderson Cancer Center,Greeley,Colorado,United States,85234[6]Florida Cancer Specialists[7]Department of Oncology,Fort Myers,Florida,United States,33901-8101[8]Woodlands Medical Specialists, P.A.,Pensacola,Florida,United States,32503[9]Cancer Care Centers of Brevard,Rockledge,Florida,United States,32955[10]Florida Cancer Specialist, North Region,Saint Petersburg,Florida,United States,33705[11]Northwest Georgia Oncology Centers PC - Marietta,Marietta,Georgia,United States,30060[12]Illinois Cancer Care,Peoria,Illinois,United States,61615[13]New England Cancer Specialists,Brunswick,Maine,United States,04011[14]Southcoast Health System,Fairhaven,Massachusetts,United States,02719[15]Minnesota Oncology Hematology,Saint Paul,Minnesota,United States,55102[16]HCA Midwest Health,Kansas City,Missouri,United States,64132[17]Cox Health Systems,Springfield,Missouri,United States,65807[18]Optum Health Care,Las Vegas,Nevada,United States,89102[19]Comprehensive Cancer Centers of Nevada,Las Vegas,Nevada,United States,89128[20]Titan Health Partners LLC, d/b/a Astera Cancer Care,East Brunswick,New Jersey,United States,08816[21]San Juan Oncology Associates,Farmington,New Mexico,United States,87401[22]New York Oncology Hematology,P.C.-Albany,Albany,New York,United States,12208[23]Montefiore Medical Center,Bronx,New York,United States,10467[24]Mount Sinai Medical Center,New York,New York,United States,10029[25]Prisma Health ? Upstate,Greenville,South Carolina,United States,29615[26]Tennessee Oncology Chattanooga,Chattanooga,Tennessee,United States,37404[27]Tennessee Oncology[28]Sarah Cannon Research Institute,Nashville,Tennessee,United States,37203[29]Virginia Cancer Specialists,Fairfax,Virginia,United States,22031[30]Virginia Oncology Associates,Norfolk,Virginia,United States,23502[31]Cemic[32]Oncologia Clinica,Buenos Aires,Argentina,C1431FWN[33]Hospital Britanico de Buenos Aires,Ciudad Autonoma Buenos Aires,Argentina,C1284AEB[34]Clinica Universitaria Reina Fabiola,Cordoba,Argentina,X5004FHP[35]Sanatorio Parque S.A.,Rosario,Argentina,S2000QGB[36]Blacktown Hospital,Blacktown,New South Wales,Australia,2148[37]Macarthur Cancer Therapy Centre,Campbelltown,New South Wales,Australia,2560[38]St George Hospital[39]Cancer Care Centre,Kogarah,New South Wales,Australia,2217[40]Princess Alexandra Hospital,Woolloongabba,Queensland,Australia,4102[41]Flinders Medical Centre,Bedford Park,South Australia,Australia,5042[42]Fiona Stanley Hospital[43]FSH Cancer Centre Clinical Trials Unit,Bull Creek,Western Australia,Australia,6149[44]Monash Health Translational Precinct[45]Clinical Trials Centre, Level 3,Victoria,Australia,3168[46]Tiroler Landeskrankenanstalten Ges.M.B.H.[47]Innere Medizin Abt. Für Hämatologie & Onkologie,Innsbruck,Austria,6020[48]Kepler Universitätskliniken GmbH - Med Campus III[49]Abt. Für Lungenkrankheiten,Linz,Austria,4020[50]Klinik Penzing[51]Abteilung für Atemwegs- und Lungenkrankheiten,Wien,Austria,1140[52]GHdC Site Notre Dame,Charleroi,Belgium,6000[53]AZ Maria Middelares,Gent,Belgium,9000[54]Jessa Zkh (Campus Virga Jesse),Hasselt,Belgium,3500[55]Hospital Sao Rafael - HSR,Salvador,BA,Brazil,41253-190[56]Crio - Centro Regional Integrado de Oncologia,Fortaleza,CE,Brazil,60336-232[57]Centro Integrado de Oncologia de Curitiba,Curitiba,PR,Brazil,80810-050[58]Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda,Ijui,RS,Brazil,98700-000[59]Hospital Sao Lucas - PUCRS,Porto Alegre,RS,Brazil,90610-000[60]Hospital de Cancer de Barretos,Barretos,SP,Brazil,14784-400[61]Hospital de Base de Sao Jose do Rio Preto,Sao Jose do Rio Preto,SP,Brazil,15090-000[62]Instituto do Cancer do Estado de Sao Paulo - ICESP,Sao Paulo,SP,Brazil,01246-000[63]BC Cancer ? Abbotsford,Abbotsford,British Columbia,Canada,V2S 0C2[64]BC Cancer - Victoria,Victoria,British Columbia,Canada,V8R 6V5[65]Cancer Care Manitoba,Winnipeg,Manitoba,Canada,R3E 0V9[66]Royal Victoria Regional Health Centre[67]c/o Oncology Clinical Trials,Barrie,Ontario,Canada,L4M 6M2[68]William Osler Health System Brampton Civic Hospital,Brampton,Ontario,Canada,L6R 3J7[69]Ottawa Hospital Research Institute,Ottawa,Ontario,Canada,K1Y 4E9[70]Health Sciences North,Sudbury,Ontario,Canada,P3E 5J1[71]Peking Union Medical College Hospital,Beijing City,China,100032[72]Beijing Cancer Center[73]Renal Cancer And Melanoma Department.,Beijing City,China,100142[74]Beijing Chest Hospital[75]Oncology Department,Beijing,China,101149[76]Jilin Cancer Hospital,Changchun,China,132013[77]Xiangya Hospital Central South University,Changsha City,China,410008[78]Changzhou Cancer hospital,Changzhou,China,213000[79]Sichuan Provincial Cancer Hospital,Chengdu,China,610041[80]Chongqing Cancer Hospital,Chongqing,China,400030[81]Fujian Medical University Union Hospital,Fuzhou City,China,350001[82]Fujian Provincial Cancer Hospital,Fuzhou City,China,350014[83]Cancer Center, Sun Yat-sen University of Medical Sciences[84]Department of Medical Oncology,Guangzhou City,China,510060[85]Hangzhou Cancer Hospital,Hangzhou City,China,310002[86]Sir Run Run Shaw Hospital Zhejiang University,Hangzhou City,China,310016[87]Shandong Cancer Hospital,Jinan,China,250117
研究目的：
The purpose of this study is to evaluate the efficacy and safety of atezolizumab in combination with tiragolumab compared with durvalumab in participants with locally advanced, unresectable Stage III non-small cell lung cancer (NSCLC) who have received at least two cycles of concurrent platinum-based chemoradiotherapy (CRT) and have not had radiographic disease progression.
