研究单位:[1]Jilin Provincial Tumor Hospital[2]BeiGene[3]The Second Hospital of Anhui Medical University,Hefei,Anhui,China,230601[4]Beijing Hospital,Beijing,Beijing,China,100005[5]China-Japan Friendship Hospital,Beijing,Beijing,China,100029[6]Chinese PLA General Hospital,Beijing,Beijing,China,100039[7]The Third Hospital of Peking University,Beijing,Beijing,China,100191[8]Peking Union Medical College Hospital, Chinese Academy of Medical Sciences,Beijing,Beijing,China,100730[9]Name:Peking University International Hospital,Beijing,Beijing,China,102206[10]Beijing Cancer Hospital,Beijing,Beijing,China[11]Army Special Medical Center (Daping Hospital),Chongqing,Chongqing,China,400042[12]Fujian Cancer Hospital,Fuzhou,Fujian,China,350014[13]Fujian Medical University Union Hospital,Fuzhou,Fujian,China,361003[14]First Affiliated Hospital of Xiamen University,Xiamen,Fujian,China,361003[15]First Hospital of Lanzhou University,Lanzhou,Gansu,China,730000[16]Cancer Center of Guangzhou Medical University,Guangzhou,Guangdong,China,510059[17]The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong,China,510059[18]Guangdong Provincial People's Hospital,Guangzhou,Guangdong,China,510080[19]Affiliated Hospital of Guilin Medical University,Guilin,Guangxi,China,541001[20]Guangxi Zhuang Autonomous Region People''s Hospital,Nanning,Guangxi,China,168600[21]Affiliated Tumor Hospital of Guangxi Medical University,Nanning,Guangxi,China,530021[22]Affiliated Tumor Hospital of Harbin Medical University,Harbin,Heilongjiang,China,150081[23]Henan Cancer Hospital,Zhengzhou,Henan,China,450008[24]First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China,450052[25]Tongji Hospital Tongji Medical College Huazhong University of Sciences and Technology,Wuhan,Hubei,China,430000[26]Union Hospital Tongji Medical College Huazhong University of Sciences and Technology,Wuhan,Hubei,China,430000[27]The Central Hospital Wuhan,Wuhan,Hubei,China,430014[28]Hunan Cancer Hospital,Changsha,Hunan,China,410006[29]Xiangya Hospital, Central South University,Changsha,Hunan,China,410008[30]Changsha Central Hospital,Changsha,Hunan,China,410018[31]General Hospital of Nanjing Military Command,Nanjing,Jiangsu,China,210002[32]Nanjing Chest Hospital,Nanjing,Jiangsu,China,210029[33]The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215006[34]Jilin Cancer Hospital,Changchun,Jilin,China,130012[35]The First Affiliated Hospital of China Medical University,Shenyang,Liaoning,China,110001[36]Liaoning Cancer Hospital,Shenyang,Liaoning,China,110042[37]Jinan Central Hospital,Jinan,Shandong,China,250013[38]Shandong Cancer Hospital,Jinan,Shandong,China,250117[39]Affiliated hospital of Qingdao University,Qingdao,Shandong,China,266003[40]Yantai Yuhuangding Hospital,Yantai,Shandong,China,264000[41]Shanghai Chest Hospital,Shanghai,Shanghai,China,200030[42]Shanghai Pulmonary Hospital,Shanghai,Shanghai,China,200433[43]Shannxi Provincial Cancer Hospital,Xi''an,Shannxi,China,710061[44]The First Affiliated Hospital of Xi ''an Jiaotong University,Xi''an,Shannxi,China,710061[45]West China Hospital · Sichuan University,Chengdu,Sichuan,China,610041[46]Sichuan Cancer Hospital,Chengdu,Sichuan,China,610042[47]Tianjin Cancer Hospital,Tianjin,Tianjin,China,300060[48]General Hospital of Tianjin Medical University,Tianjin,Tianjin,China,300070[49]Affiliated Tumor Hospital of Xinjiang Medical University,Ürümqi,Xinjiang,China,830000[50]Yunnan Cancer Hospital,Kunming,Yunnan,China,650118[51]The First Affiliated Hospital of Zhejiang University Medical College,Hangzhou,Zhejiang,China,310003[52]Zhejiang Cancer Hospital,Hangzhou,Zhejiang,China,310022
研究目的:
This is a randomized, double-blind, placebo-controlled, multicenter, Phase 3 study to compare the efficacy of tislelizumab + cisplatin or carboplatin + etoposide (Arm A) and placebo + cisplatin or carboplatin + etoposide (Arm B) as first-line treatment in approximately 455 participants who have previously untreated extensive-stage small cell lung cancer (ES-SCLC)