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Assessment of the Minimal Residual Disease in Ovarian Cancer From Circulating Tumor DNA and Immune Repertoire

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研究单位: [1]Geneplus-Beijing Co. Ltd. [2]Peking Union Medical College Hospital [3]Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University,Changsha,Hunan,China [4]The First Affiliated Hospital of Xi'an Jiaotong University,Xi''an,Shaanxi,China [5]Sichuan Cancer Hospital,Chengdu,Sichuan,China [6]Affiliated Cancer Hospital of Xinjiang Medical University,Ürümqi,Xinjiang,China [7]Peking Union Medical College Hospital,Beijing,China [8]Peking University International Hospital,Beijing,China

研究目的:
To analyze the proportion of hereditary tumors in ovarian cancer patients in China, as well as the spectrum of variations; the ctDNA characteristics in patients with ovarian cancer; the correlation between the clonal status of mutations and therapy response; whether ctDNA detection can be used to predict the risk of ovarian cancer recurrence; and the characteristics of immune repertoire before and after treatment in patients with ovarian cancer.

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