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A Study of Comparison of TACE Combination With and Without EBRT for Advanced HCC

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研究单位: [1]Shanghai Zhongshan Hospital [2]Changhai Hospital [3]Shanghai 10th People's Hospital [4]First Affiliated Hospital of Zhejiang University [5]The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School [6]Fujian Cancer Hospital [7]First Affiliated Hospital of Fujian Medical University [8]Zhongshan Hospital Xiamen University [9]West China Hospital [10]Peking University Cancer Hospital & Institute [11]Xinqiao Hospital of Chongqing [12]309th Hospital of Chinese People's Liberation Army [13]Heilongjiang Provincial Agricultural Reclamation General Hospital [14]Longyan First Hospital, Affiliated to Fujian Medical University [15]Peking University First Hospital [16]The Third Affiliated Hospital of Qiqihar Medical Universitiy [17]Anhui Provincial Hospital [18]First Affiliated Hospital of Xinjiang Medical University [19]Qingdao University [20]The 4th people's hospital of Wuxi City, Affiliated to Jiangnan University [21]Subei People's Hospital of Jiangsu Province,Yangzhou University [22]The Affiliated Zhongshan Hospital of Dalian University [23]Jilin University [24]First Affiliated Hospital of Guangxi Medical University [25]Fudan University [26]Shanghai East Hospital,Tongji University School of Medicine [27]Chinese PLA General Hospital [28]The 4th People's Hospital of Linfen City [29]Nanfang Hospital of Southern Medical University [30]Yunnan Cancer Hospital [31]Shandong Cancer Hospital and Institute [32]Sichuan Cancer Hospital and Research Institute [33]First Affiliated Hospital, Sun Yat-Sen University [34]The Second Affiliated Hospital of Chongqing Medical University [35]Fujian Medical University Union Hospital [36]The People's Hospital of Hunan Province

关键词: Hepatocellular Carcinoma external- beam radiotherapy (EBRT) transarterial chemoembolization (TACE)

研究目的:
This clinical trial is a prospective, randomized, controlled and multicenter study.And the trial is going to better control intrahepatic tumors for hepatocellular carcinoma(HCC) patients who meet the inclusion criterion.The patients were divided into two groups, the group A by TACE and the other group B by external- beam radiotherapy(EBRT) after 2 times TACE. Then the therapeutic effects and toxicities of TACE and EBRT are evaluated during the follow-up period. The study design plans to enroll 300 patients, and each group includes 150 cases.

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