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Outcome of primary intraosseous carcinoma: Case review of a single institution.

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WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Long En[1] * ; You Dongling[1] * ; Wang Shubin[2] * ; Lu Shun[3,4] ; Xu Peng[3] ; Zhou Jie[3] ; Li Lu[3] ; Wu Jian[1] ; Zhang Biqin[2] ; Zhu Guiquan[5,6,*1] ; Lang Jinyi[1,3,4,*2] ;
机构： [1]Department of Oncology, Southwest Medical University, Luzhou, China. [2]School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. [3]Department of radiation oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Prevention and Control Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. [4]Department of Radiological Protection, Radiation Oncology Key Laboratory of Sichuan Province, Chengdu, China. [5]Department of Head and Neck Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Prevention and Control Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. [6]State Key Laboratory of Oral Diseases, Department of Head and Neck Oncology, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
出处：
DOI： 10.1111/odi.14233
ISSN：

关键词： oral cancer primary intraosseous carcinoma prognosis radiotherapy

摘要：
The purpose of this study was to investigate the prognostic factors and treatment of primary intraosseous carcinoma (PIOC).Patients diagnosed with POIC and received treatment in Sichuan Cancer Hospital from 2000 to 2019 were followed up and retrospectively reviewed.A total of 28 patients were included in the study, with a mean age of 60 years (60 ± 10.11). The 2-year and 5-year overall survival (OS) were 60.7% and 38.5%, respectively. In the univariate analysis, surgery combined with adjuvant therapy improved the OS compared with surgery or radiotherapy alone (p = 0.035), and patients who received postoperative adjuvant radiotherapy had a higher OS than those who received radical radiotherapy (p = 0.01). In addition, patients with well-differentiated tumors have increased progression-free survival (p = 0.01). Multivariate analyses showed that radiotherapy was an independent indicator for OS (p = 0.007).Surgery combined with adjuvant therapy is the superior treatment strategy for PIOC at present. This study is the first to confirm the positive role of radiotherapy in treating PIOC with data to back it up.© 2022 The Authors. Oral Diseases published by Wiley Periodicals LLC.

基金：
National Natural Science Foundation of China, Grant/Award Number: 81672690 and 81872196; Department of Science and Technology of Sichuan Province, Grant/Award Number: 2021JDRC0146 and 2021YFH0138
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类 | 3 区 医学
小类 | 4 区 牙科与口腔外科
最新[2023]版：
大类 | 3 区 医学
小类 | 4 区 牙科与口腔外科
JCR分区：
出版当年[2023]版：
Q1 DENTISTRY, ORAL SURGERY & MEDICINE
最新[2023]版：
Q1 DENTISTRY, ORAL SURGERY & MEDICINE

影响因子： 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

第一作者：
第一作者机构： [1]Department of Oncology, Southwest Medical University, Luzhou, China.
共同第一作者：
通讯作者：
通讯机构： [1]Department of Oncology, Southwest Medical University, Luzhou, China. [3]Department of radiation oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Prevention and Control Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. [4]Department of Radiological Protection, Radiation Oncology Key Laboratory of Sichuan Province, Chengdu, China. [5]Department of Head and Neck Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Prevention and Control Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. [6]State Key Laboratory of Oral Diseases, Department of Head and Neck Oncology, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. [*1]Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, No. 14, Section 3, Renmin South Road, 610041 Chengdu, Sichuan, PR China. [*2]Department of radiation oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Prevention and Control Center, School of Medicine, University of Electronic Science and Technology of China, 610041 Chengdu, China.
推荐引用方式(GB/T 7714)：
Long En,You Dongling,Wang Shubin,et al.Outcome of primary intraosseous carcinoma: Case review of a single institution.[J].ORAL DISEASES.2023,29(5):2027-2033.doi:10.1111/odi.14233.
APA：
Long En,You Dongling,Wang Shubin,Lu Shun,Xu Peng...&Lang Jinyi.(2023).Outcome of primary intraosseous carcinoma: Case review of a single institution..ORAL DISEASES,29,(5)
MLA：
Long En,et al."Outcome of primary intraosseous carcinoma: Case review of a single institution.".ORAL DISEASES 29..5(2023):2027-2033

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