机构：[1]School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610041四川省人民医院[2]College of Physical Education, Sichuan Agricultural University, Ya'an, Sichuan 625000[3]Second Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000[4]Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Radiation Oncology Key Laboratory of Sichuan Province, Chengdu, Sichuan 610041, P.R. China四川省人民医院四川省肿瘤医院
Colorectal cancer is the third most common type of cancer, with high morbidity and mortality rates. In particular, locally advanced rectal cancer (LARC) is difficult to treat and has a high recurrence rate. Neoadjuvant chemoradiotherapy (NCRT) is one of the standard treatment programs of LARC. If the response to treatment and prognosis in patients with LARC can be predicted, it will guide clinical decision‑making. Radiomics is characterized by the extraction of high‑dimensional quantitative features from medical imaging data, followed by data analysis and model construction, which can be used for tumor diagnosis, staging, prediction of treatment response and prognosis. In recent years, a number of studies have assessed the role of radiomics in NCRT for LARC. MRI‑based radiomics provides valuable data and is expected to become an imaging biomarker for predicting treatment response and prognosis. The potential of radiomics to guide personalized medicine is widely recognized; however, current limitations and challenges prevent its application to clinical decision‑making. The present review summarizes the applications, limitations and prospects of MRI‑based radiomics in LARC.
基金：
Sichuan Science and Technology Program (grant no. 2021YFG0320 and 2020YJ0446).
第一作者机构：[1]School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610041
共同第一作者：
通讯作者：
通讯机构：[4]Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Radiation Oncology Key Laboratory of Sichuan Province, Chengdu, Sichuan 610041, P.R. China[*1]Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Radiation Oncology Key Laboratory of Sichuan Province, 55 Section 4 South Renmin Road, Wuhou, Chengdu, Sichuan 610041, P.R. China
推荐引用方式(GB/T 7714)：
Zhang Siyu,Yu Mingrong,Chen Dan,et al.Role of MRI‑based radiomics in locally advanced rectal cancer (Review).[J].ONCOLOGY REPORTS.2022,47(2):doi:10.3892/or.2021.8245.
APA：
Zhang Siyu,Yu Mingrong,Chen Dan,Li Peidong,Tang Bin&Li Jie.(2022).Role of MRI‑based radiomics in locally advanced rectal cancer (Review)..ONCOLOGY REPORTS,47,(2)
MLA：
Zhang Siyu,et al."Role of MRI‑based radiomics in locally advanced rectal cancer (Review).".ONCOLOGY REPORTS 47..2(2022)
