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Expert consensus on perioperative immunotherapy for local advanced non-small cell lung cancer

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机构: [1]Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China [2]Department of Thoracic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China [3]Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China [4]Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, China [5]Department of Thoracic Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China [6]Department of Thoracic Surgery, Cancer Hospital of University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China [7]Institute of Cancer and Basic Medicine (IBMC), Chinese Academy of Science, Hangzhou, China [8]Department of Thoracic Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China [9]Department of Thoracic Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China [10]Department of Thoracic Surgery, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China [11]Department of Thoracic Surgery, Jiangsu Cancer Hospital (Nanjing Medical University Affiliated Cancer Hospital) and Jiangsu Institute of Cancer Research, Nanjing, China [12]Department of Thoracic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China [13]Department of Thoracic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China [14]Department of Thoracic Surgery, Yunnan Cancer Hospital, Kunming, China [15]Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China [16]Department of Thoracic Surgery, The First Affiliated Hospital of Xiamen University, Xiamen, China [17]Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi’an, China [18]Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China [19]Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China [20]Department of Thoracic Surgery, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China [21]Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China [22]Department of Thoracic Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, China [23]Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China [24]Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China [25]Department of Thoracic Surgery, Chinese PLA General Hospital, Beijing, China [26]Department of Thoracic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China [27]Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China [28]Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China [29]Department of Thoracic Surgery, Tumor Hospital Affiliated to Guangxi Medical University, Nanning, China [30]Department of Thoracic Surgery, Fujian Provincial Hospital, Fuzhou, China [31]Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China [32]Department of Thoracic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China [33]Department of Cardiothoracic Surgery, Affiliated Taikang Xianlin Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China [34]Department of Thoracic Surgery II, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, China [35]Henan Provincial People’s Hospital, Zhengzhou, China [36]Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China [37]Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China [38]Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China [39]Department of Thoracic Surgery, Harbin Medical University Cancer Hospital, Harbin, China [40]Department of Thoracic Surgery, Shenzhen People’s Hospital, 2nd Clinical Medical College of Jinan University, Shenzhen, China [41]Department of Thoracic Cardiovascular Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China [42]Department of Thoracic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangdong Esophageal Cancer Institute, Guangzhou, China [43]Department of Thoracic Surgery, Xuanwu Hospital of Capital Medical University, Beijing, China [44]Department of Lung Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China [45]Department of Thoracic Surgery, Fujian Cancer Hospital and Fujian Medical University Cancer Hospital, Fuzhou, Fujian, China [46]Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China [47]Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea [48]Department of Internal Medicine, Chonnam National University Medical School and Hwasun Hospital, Jeonnam, Korea [49]Department of Respiratory Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan [50]Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan [51]Department of Thoracic Surgery, Aichi Cancer Center Hospital, Nagoya, Japan [52]Division of Medical Oncology, Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan [53]Lung Cancer Center, Central Japan International Medical Center, Gifu, Japan [54]Department of Respiratory Medicine, Tokyo Saiseikai Central Hospital, Tokyo, Japan [55]Department of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan [56]Department of Tumor Pathology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan [57]Department of Medical Oncology and Translational Research Institute, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar [58]Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy [59]Imaging Institute of the Southern Switzerland (IIMSI), Ente Ospedaliero Cantonale (EOC), Università della Svizzera Italiana, Lugano, Switzerland [60]Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, China [61]Department of Thoracic Surgery, University Campus Bio-Medico, Rome, Italy [62]Precision Medicine Lung Cancer Center, Konkuk University Medical Center, Seoul, Korea [63]Department of Radiation Oncology, MAASTRO Clinic, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands [64]Division of Hematology, Oncology and Blood and Marrow Transplantation, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA [65]Department of Radiology and Biomedical Engineering, University of Iowa, Iowa City, IA, USA [66]Department of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA [67]Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA [68]Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA [69]Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy [70]Department of Medical Oncology, The Christie NHS Foundation Trust and Division of Cancer Sciences, The University of Manchester, Manchester, UK [71]Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy [72]Medical Oncology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain [73]Laboratory of Clinical and Experimental Pathology, FHU OncoAge, Pasteur Hospital, BB-0033- 00025, CHU Nice, Université Côte d’Azur, Nice, France
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摘要:
The treatment of lung cancer is one of the major challenges in the field of oncology. According to statistics from the National Cancer Center of China in 2015, lung cancer has the highest incidence and mortality, with 733,300 new cases and 610,200 deaths across the country (1). About 85% of lung cancers are non-small cell lung cancer (NSCLC), of which 30% to 40% are considered resectable tumors, including most stage I-II and a small portion of stage IIIA tumors (2). Very early-stage NSCLC (IA) can be cured by surgery. However, more than 50% of NSCLC patients who undergo surgical treatment will relapse or metastasize within 5 years. Even if there is no lymph node metastasis and the primary

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大类 | 2 区 医学
小类 | 2 区 肿瘤学 2 区 呼吸系统
最新[2023]版:
大类 | 2 区 医学
小类 | 3 区 肿瘤学 3 区 呼吸系统
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出版当年[2021]版:
Q2 ONCOLOGY Q2 RESPIRATORY SYSTEM
最新[2023]版:
Q1 RESPIRATORY SYSTEM Q2 ONCOLOGY

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第一作者机构: [1]Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
通讯作者:
通讯机构: [1]Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China [*1]Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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