机构：[1]Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangdong, Guangzhou, China[2]Jibla University for Medical Sciences, Jibla Hospital, Ibb City, Yemen[3]Guanghua Stomatology Hospital, Sun Yat-Sen University, Guangdong, Guangzhou, China[4]Department of Craniomaxillofacial and Plastic Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt[5]State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China[6]Department of Oral Pathology, Dalian Medical University, China[7]Maxillofacial Surgery Unit, General Surgery Department, Faculty of Medicine, Assiut University, Assiut, Egypt
An evidence regarding which bony flap for reconstruction of mandibular defects following tumour resection is associated with the highest survival rate is still lacking. This network meta-analysis (NMA) aimed to guide surgeons selecting which vascularized osseous flap is associated with the highest survival rate for mandibular reconstruction.From inception to March 2021, PubMed, Embase, Scopus, and Cochrane library were searched to identify the eligible studies. The outcome variable was the flap survival rate. The Bayesian NMA accompanied by a random effect model and 95% credible intervals (CrI) was calculated.Twenty-two studies with a total of 1513 patients, comparing four osseous flaps namely fibula free flap (FFF), deep circumferential iliac artery flap (DCIA), scapula flap, and osteocutaneous radial forearm flap (ORFF) were included. The respective survival rates of FFF, DCIA, Scapula, and ORFF were 94.50%, 93.12%, 97%, and 95.95%. The NMA failed to show a statistically significant difference between all comparators (FFF versus DCIA (Odd ratio, 1.8; CrI, 0.58,5.0); FFF versus ORFF (Odd ratio, 0.57; CrI, 0.077; 2.9); FFF versus scapula flap (Odd ratio, 0.25; CrI, 0.026; 1.5); DCIA versus ORFF (Odd ratio, 0.32; CrI, 0.037; 2.1); DCIA versus scapula flap (Odd ratio, 0.14; CrI, 0.015; 1.1) and ORFF versus scapula flap (Odd ratio, 2.3; CrI, 0.16; 34)).Within the limitations of the current NMA, FFF, DCIA, Scapula, and ORFF showed a comparable survival rate for mandibular reconstruction. Although the scapula flap reported the highest survival rate compared to other osseous flaps for mandibular reconstruction; however, the decision making when choosing an osseous flap should be based on many factors rather than simply flap survival rate.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类|3 区综合性期刊
小类|3 区综合性期刊
最新[2023]版：
大类|3 区综合性期刊
小类|3 区综合性期刊
第一作者：
第一作者机构：[1]Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangdong, Guangzhou, China[2]Jibla University for Medical Sciences, Jibla Hospital, Ibb City, Yemen
共同第一作者：
通讯作者：
通讯机构：[1]Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangdong, Guangzhou, China[2]Jibla University for Medical Sciences, Jibla Hospital, Ibb City, Yemen
推荐引用方式(GB/T 7714)：
Mashrah Mubarak Ahmed,Aldhohrah Taghrid,Abdelrehem Ahmed,et al.Survival of vascularized osseous flaps in mandibular reconstruction: A network meta-analysis.[J].PloS one.2021,16(10):e0257457.doi:10.1371/journal.pone.0257457.
APA：
Mashrah Mubarak Ahmed,Aldhohrah Taghrid,Abdelrehem Ahmed,Sakran Karim Ahmed,Ahmad Hyat...&Wang Liping.(2021).Survival of vascularized osseous flaps in mandibular reconstruction: A network meta-analysis..PloS one,16,(10)
MLA：
Mashrah Mubarak Ahmed,et al."Survival of vascularized osseous flaps in mandibular reconstruction: A network meta-analysis.".PloS one 16..10(2021):e0257457
