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Potential Strategies to Improve the Effectiveness of Drug Therapy by Changing Factors Related to Tumor Microenvironment.

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机构： [1]Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China [2]West China School of Medicine, Sichuan University, Chengdu, China

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关键词： tumor microenvironment cancer-associated fibroblasts tumor-associated macrophages drug therapy targeted therapy

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A tumor microenvironment (TME) is composed of various cell types and extracellular components. It contains tumor cells and is nourished by a network of blood vessels. The TME not only plays a significant role in the occurrence, development, and metastasis of tumors but also has a far-reaching impact on the effect of therapeutics. Continuous interaction between tumor cells and the environment, which is mediated by their environment, may lead to drug resistance. In this review, we focus on the key cellular components of the TME and the potential strategies to improve the effectiveness of drug therapy by changing their related factors.Copyright © 2021 Cao, Naiyila, Li, Huang, Chen, Chen, Li, Guo, Dong, Ai, Yang, Liu and Wei.

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出版当年[2021]版：

大类 | 3 区生物学

小类 | 2 区发育生物学 3 区细胞生物学

最新[2023]版：

大类 | 2 区生物学

小类 | 2 区发育生物学 3 区细胞生物学

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第一作者机构： [1]Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, China

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