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A lipid droplet targeted fluorescent probe for high-efficiency image-guided photodynamic therapy of renal cell carcinoma.

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机构: [1]Department of Urology, Institute of Urology, Huaxi MR Research Center (HMRRC), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610064, P. R. China [2]Laboratory of Heart Valve Disease, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610064, P. R. China [3]Department of Cardiology, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610064, P. R. China
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摘要:
A one-step synthesized LD specific fluorescent probe TTIE with high specificity, good photostability and great capacity in generating cytotoxic reactive oxygen species (ROS) under low powered white light irradiation is designed and synthesized for LD specific image-guided photodynamic therapy (PDT) in human clear cell renal cell carcinoma (ccRCC) primary cells and tissues.

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出版当年[2021]版:
大类 | 2 区 化学
小类 | 2 区 化学综合
最新[2023]版:
大类 | 2 区 化学
小类 | 3 区 化学:综合
第一作者:
第一作者机构: [1]Department of Urology, Institute of Urology, Huaxi MR Research Center (HMRRC), State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610064, P. R. China
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通讯作者:
通讯机构: [2]Laboratory of Heart Valve Disease, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610064, P. R. China [3]Department of Cardiology, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610064, P. R. China
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