机构：[1]Department of Surgery, School of Medicine,Kyungpook National University [2]Department of Plastic Surgery, School of Medicine,Kyungpook National University [3]Kyungpook National University Chilgok Hospital [4]Kyungpook National University Hospital, Daegu, Korea [5]Department of Surgery, Sichuan Province Cancer Hospital, Chengdu, China, 四川省肿瘤医院[6]Joint Institute for Regenerative Medicine, Kyungpook National University, Daegu, Korea.
Filling materials for partial defect of the breast have rarely been developed because of safety and durability.
Two female patients (ages, 53 and 50 years) with breast cancer underwent partial mastectomy with sentinel lymph node biopsy.
Core needle biopsy revealed an invasive ductal carcinoma in both patients. Breast ultrasound showed hypoechoic nodules with irregular margins. Breast magnetic resonance imaging showed an irregularly shaped enhancing mass with duct extension in Patient 1 and irregularly shaped multifocal, enhancing masses with non-mass enhancement in Patient 2.
A combination method using acellular dermal matrix and oxidized regenerated cellulose was used for partial breast reconstruction. The safety and cosmetic outcomes were evaluated for both patients.
There were no significant complications, and the breast shape and volume were well maintained, even 2 years after surgery. There was no postoperative tumor recurrence.
The combination of acellular dermal matrix and oxidized regenerated cellulose for partial breast reconstruction can be a good option based on oncological safety and cosmetic outcome.
基金：
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (2014R1A5A2009242, 2019R1F1A1063853)
and by a grant from the National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea (1420040). And this research was supported by
a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare,
Republic of Korea (HI17C1142). This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (NRF-
2019R1A2C1006264). This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (2017M3A9G8083382)
第一作者机构：[1]Department of Surgery, School of Medicine,Kyungpook National University [3]Kyungpook National University Chilgok Hospital
通讯作者：
通讯机构：[1]Department of Surgery, School of Medicine,Kyungpook National University [3]Kyungpook National University Chilgok Hospital [6]Joint Institute for Regenerative Medicine, Kyungpook National University, Daegu, Korea. [*1]Department of Surgery, School of Medicine, Kyungpook National University, Hoguk-ro 807, Buk-gu, Daegu 41404, Republic of Korea
推荐引用方式(GB/T 7714)：
Lee Jeeyeon,Yang Jung Dug,Lee Jeong Woo,et al.Acellular dermal matrix combined with oxidized regenerated cellulose for partial breast reconstruction: Two case reports.[J].MEDICINE.2020,99(31):doi:10.1097/MD.0000000000021217.
APA：
Lee Jeeyeon,Yang Jung Dug,Lee Jeong Woo,Li Junjie,Jung Jin Hyang...&Park Ho Yong.(2020).Acellular dermal matrix combined with oxidized regenerated cellulose for partial breast reconstruction: Two case reports..MEDICINE,99,(31)
MLA：
Lee Jeeyeon,et al."Acellular dermal matrix combined with oxidized regenerated cellulose for partial breast reconstruction: Two case reports.".MEDICINE 99..31(2020)
