机构：[1]China Academy of Engineering Physics, Institute of Fluid Physics, Interdisciplinary Laboratory of Physics and Biomedicine, No. 64, Mianshan Road, Mianyang, Sichuan 621900, China[2]China Academy of Engineering Physics, Terahertz Research Center, Mianyang, Sichuan 621900, China[3]Third Military Medical University, Southwest Hospital, Department of Neurosurgery, No. 30, Gaotanyan Street, Shapingba, Chongqing 400038, China
The refractive indices, absorption coefficients, and complex dielectric constants of paraffin-embedded brain glioma and normal brain tissues have been measured by a terahertz time-domain spectroscopy (THz-TDS) system in the 0.2- to 2.0-THz range. The spectral differences between gliomas and normal brain tissues were obtained. Compared with normal brain tissue, our results indicate that paraffin-embedded brain gliomas have a higher refractive index, absorption coefficient, and dielectric constant. Based on these results, the best THz frequencies for different methods of paraffin-embedded brain glioma imaging, such as intensity imaging, coherent imaging with continuum THz sources, and THz pulsed imaging with short-pulsed THz sources, are analyzed.
基金：
NSAF (Grant No. U1230128),
NSFC (Grant No. 61205100), Key Foundation of CAEP (Grant
No. 2012A0401016), CPSF (Grant No. 2014M552542XB),
NSF of Chongqing (Grant No. cstc2012jjB0081), and the
Incubation Foundation of Interdisciplinary Laboratory of
Physics and Biomedicine
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2014]版：
大类|3 区医学
小类|2 区光学3 区生化研究方法3 区核医学
最新[2023]版：
大类|3 区医学
小类|2 区生化研究方法3 区光学3 区核医学
第一作者：
第一作者机构：[1]China Academy of Engineering Physics, Institute of Fluid Physics, Interdisciplinary Laboratory of Physics and Biomedicine, No. 64, Mianshan Road, Mianyang, Sichuan 621900, China[2]China Academy of Engineering Physics, Terahertz Research Center, Mianyang, Sichuan 621900, China
共同第一作者：
通讯作者：
通讯机构：[1]China Academy of Engineering Physics, Institute of Fluid Physics, Interdisciplinary Laboratory of Physics and Biomedicine, No. 64, Mianshan Road, Mianyang, Sichuan 621900, China[2]China Academy of Engineering Physics, Terahertz Research Center, Mianyang, Sichuan 621900, China
推荐引用方式(GB/T 7714)：
Meng Kun,Chen Tu-nan,Chen Tao,et al.Terahertz pulsed spectroscopy of paraffin-embedded brain glioma.[J].Journal of biomedical optics.2014,19(7):077001.doi:10.1117/1.JBO.19.7.077001.
APA：
Meng Kun,Chen Tu-nan,Chen Tao,Zhu Li-guo,Liu Qiao...&Zhao Jian-heng.(2014).Terahertz pulsed spectroscopy of paraffin-embedded brain glioma..Journal of biomedical optics,19,(7)
MLA：
Meng Kun,et al."Terahertz pulsed spectroscopy of paraffin-embedded brain glioma.".Journal of biomedical optics 19..7(2014):077001
