机构：[1]Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China,四川大学华西医院[2]Department of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China,[3]Department of Evidence-Based Medicine and Clinical Epidemiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China四川大学华西医院
The inflammatory potential of diet has been shown to have an association with the risk of several cancer types, but the evidence is inconsistent regarding the related risk of urologic cancer (UC). Therefore, we conducted the present meta-analysis to investigate the association between the inflammatory potential of diet and UC.
PubMed, Embase and Web of Science were searched up to July 31, 2018. Two reviewers independently selected the studies and extracted the data. The pooled risk ratio (RR) and its 95% confidence interval (CI) were calculated using the Stata12.0 software package.
Nine case-control studies and three cohort studies including 83,197 subjects met the inclusion criteria. The overall meta-analysis results showed that individuals with the highest category of DII (dietary inflammatory index) were associated with an increased risk of prostate cancer (RR = 1.62, 95% CI: 1.30-2.02); subgroup analysis showed consistent results. For kidney and bladder cancer, significant positive associations were found in individuals with the highest category of DII score; however, no significant association was found between DII and the risk of urothelial cell carcinoma (UCC).
Available data suggest that more pro-inflammatory diets are associated with an increased risk of prostate cancer, kidney cancer and bladder cancer. However, further well designed large-scaled cohort studies are warranted to provide more conclusive evidence.
基金：
Science and
Technology Support Project of Science and
Technology Department of Sichuan Province,
Grant ID: 2016FZ0103; and Key Research and
Development Project of Science and Technology
Department of Sichuan Province, Grant ID:
2017SZ0067; and 1.3.5 project for disciplines of
excellence, West China Hospital, Sichuan University; Grant ID: ZY2016104. The study
sponsor had no role in the design and conduct of
the study; collection, management, analysis and
interpretation of the data; preparation, review or
approval of the article; and decision to submit the
article for publication.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|3 区生物
小类|3 区综合性期刊
最新[2023]版：
大类|3 区综合性期刊
小类|3 区综合性期刊
第一作者：
第一作者机构：[1]Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China,
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Lu Dong-Liang,Ren Zheng-Ju,Zhang Qin,et al.Meta-analysis of the association between the inflammatory potential of diet and urologic cancer risk.[J].PloS one.2018,13(10):e0204845.doi:10.1371/journal.pone.0204845.
APA：
Lu Dong-Liang,Ren Zheng-Ju,Zhang Qin,Ren Peng-Wei,Yang Bo...&Dong Qiang.(2018).Meta-analysis of the association between the inflammatory potential of diet and urologic cancer risk..PloS one,13,(10)
MLA：
Lu Dong-Liang,et al."Meta-analysis of the association between the inflammatory potential of diet and urologic cancer risk.".PloS one 13..10(2018):e0204845
