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The choose of different surgical therapies of hepatic alveolar echinococcosis: A single-center retrospective case-control study.

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机构: [a]Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, [b]Institute of hydatid disease prevention and control, Ganze prefecture, Sichuan Province, China, [c]Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065
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关键词: hepatic alveolar echinococcosis liver transplantation palliative hepatic resection radical hepatic resection

摘要:
The aim of this study was to evaluate different surgical therapies for hepatic alveolar echinococcosis in different clinical stages.We analyze the clinical data of 115 patients who received surgical treatment in West China Hospital from January 2004 to June 2016. Among these patients, 77 cases underwent radical hepatic resection (group A, n = 77); 17 cases underwent palliative resection (group B, n = 17), and 21 cases underwent liver transplantation (group C, n = 21) with 12 cases of orthotopic liver transplantation and 9 cases of liver autotransplantation.The postoperative complication rate of radical hepatic resection group was 13.0% (10/77), which is statistically significant (P < .05) than the rate of palliative resection group 29.4% (5/17) or liver transplantation group 23.8% (5/21). The follow-up period ranged from 1 to 72 months. The overall median survival rate of radical resection was 72/77, higher than the rate of palliative group (12/17) or transplantation group (17/21), which was also statistically significant (P < .01).In our study, we believe in that all stages of hepatic alveolar echinococcosis should take active surgical interventions, and radical hepatic resection should be considered as the first-choice treatment for early stage of alveolar echinococcosis, while palliative surgery is still helpful to relieve symptoms and improve the life quality for advanced patients. Liver transplantation might also be an alternative option for the late-stage hepatic alveolar echinococcosis.

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出版当年[2018]版:
大类 | 4 区 医学
小类 | 3 区 医学:内科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
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第一作者机构: [a]Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu,
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通讯机构: [a]Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, [b]Institute of hydatid disease prevention and control, Ganze prefecture, Sichuan Province, China, [*1]Department of Liver Surgery, Division of Liver Transplantation Center, Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, 610041 China
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