机构：[1]State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy , No. 17, 3rd Section of People's South Road, Chengdu 610041 , People's Republic of China.四川大学华西医院[2]Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University , 1 Jianshe Eastern Road, Zhengzhou 450052 , People's Republic of China.[3]Department of Nephrology, West China Hospital, Sichuan University , Chengdu 610041, Sichuan , People's Republic of China.四川大学华西医院[4]Department of Urinary Surgery, West China Hospital, West China Medical School, Sichuan University , Chengdu 610041 , People's Republic of China.四川大学华西医院[5]Laboratory of Cell and Molecular Biology and State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences , Beijing 100034 , People's Republic of China.
MicroRNAs (miRNAs) are one abundant class of small, endogenous non-coding RNAs, which regulate various biological processes by inhibiting expression of target genes. miRNAs have important functional roles in carcinogenesis and development of colorectal cancer (CRC), and emerging evidence has indicated the feasibility of miRNAs as robust cancer biomarkers. This review summarizes the progress in miRNA-related research, including study of its oncogene or tumour-suppressor roles and the advantages of miRNA biomarkers for CRC diagnosis, treatment and recurrence prediction. Along with analytical technique improvements in miRNA research, use of the emerging extracellular miRNAs is feasible for CRC diagnosis and prognosis.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|2 区生物学
小类|3 区生化与分子生物学
最新[2023]版：
大类|3 区生物学
小类|3 区生化与分子生物学
第一作者：
第一作者机构：[1]State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy , No. 17, 3rd Section of People's South Road, Chengdu 610041 , People's Republic of China.[2]Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University , 1 Jianshe Eastern Road, Zhengzhou 450052 , People's Republic of China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Chen Bing,Xia Zijing,Deng Ya-Nan,et al.Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis.[J].Open biology.2019,9(1):180212.doi:10.1098/rsob.180212.
APA：
Chen Bing,Xia Zijing,Deng Ya-Nan,Yang Yanfang,Zhang Peng...&Liang Shufang.(2019).Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis..Open biology,9,(1)
MLA：
Chen Bing,et al."Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis.".Open biology 9..1(2019):180212
