Pillarenes and calixarenes showed obvious inhibition of HPV16 L1 pentamer formation via their selective binding to Arg and Lys residues at the monomer interface, which was reversible after the release of cyclic arenes. Pillarenes are more effective than calixarenes in terms of the inhibition efficiency, attributing to the different kinetics and binding affinity.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [91027027, 20934002, 21272093]; State Key Laboratory of Supramolecular Structure and Materials
第一作者机构:[1]State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012, China
推荐引用方式(GB/T 7714):
Zheng Dong-Dong,Fu Ding-Yi,Wu Yuqing,et al.Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene[J].CHEMICAL COMMUNICATIONS.2014,50(24):3201-3203.doi:10.1039/c3cc49789e.
APA:
Zheng, Dong-Dong,Fu, Ding-Yi,Wu, Yuqing,Sun, Yu-Long,Tan, Li-Li...&Yang, Ying-Wei.(2014).Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene.CHEMICAL COMMUNICATIONS,50,(24)
MLA:
Zheng, Dong-Dong,et al."Efficient inhibition of human papillomavirus 16 L1 pentamer formation by a carboxylatopillarene and a p-sulfonatocalixarene".CHEMICAL COMMUNICATIONS 50..24(2014):3201-3203