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Postoperative chemoradiotherapy versus radiotherapy alone for cervical cancer: A systematic review and meta-analysis

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收录情况: ◇ SCIE

机构: [1]Radiotherapy Department, Sichuan Cancer Hospital, Chengdu, China
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关键词: Cervical cancer chemoradiotherapy radiotherapy meta-analysisIntroduction

摘要:
The aim of this study was to compare the treatment outcomes of postoperative chemoradiotherapy (CRT) with radiotherapy (RT) alone in patients with cervical cancer. Based on articles published up to December 2014 a literature search in PubMed and EMBASE was conducted to identify eligible studies. Risk ratio (RR) and its 95% confidence interval (CI) were used as pooled statistics. A total of 4 articles consisting of 461 patients were selected for the meta-analysis. Results revealed that there were a significant overall survival improvements (RR=1.35, 95% CI: 1.15-1.60, p=0.0003), a significant reduction of local recurrence (RR=0.26, 95% CI: 0.14-0.51, p<0001) and distant recurrence (RR=0.41, 95% CI: 0.26-0.63, p<0.0001) in the patients who received postoperative CRT, comparing with the patients who received RT alone. In conclusion, the results suggest a significant benefit of CRT for patients with cervical cancer, comparing with RT alone treatment.

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出版当年[2016]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学
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出版当年[2016]版:
Q4 OBSTETRICS & GYNECOLOGY
最新[2023]版:
Q4 OBSTETRICS & GYNECOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

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第一作者机构: [1]Radiotherapy Department, Sichuan Cancer Hospital, Chengdu, China [*1]Radiotherapy Department, Sichuan Cancer Hospital, 55 of 4 section REN MIN NAN ROAD, Chengdu, 610041, China
通讯作者:
通讯机构: [1]Radiotherapy Department, Sichuan Cancer Hospital, Chengdu, China [*1]Radiotherapy Department, Sichuan Cancer Hospital, 55 of 4 section REN MIN NAN ROAD, Chengdu, 610041, China
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