机构:[a]Department of Nephrology and Institute of Nephrology, Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, Chengdu, China,四川省人民医院[b]Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Introduction: Primary mucosa-associated lymphoid tissue (MALT) lymphomas originating in thymus is rare. And, there have been few reports of patients with MALT coexisting with amyloidosis. As far as we know, this was the first case report on MALT lymphoma associated with renal amyloidosis. Patient concerns: A 57-year-old man presented with nephrotic syndrome. Further workup revealed IgM-Lambda type monoclonal gammopathy. Bone marrow biopsy showed 8% clonal plasma cells. Renal biopsy confirmed the diagnosis of Lambda light chain AL amyloidosis. positron emission tomography/computed tomography showed thymic lesions which upon biopsy were diagnosed as MALT lymphoma of the thymus. Diagnosis: Primary thymic MALT lymphoma complicated with renal amyloidosis. Interventions: The patient underwent surgical resection of the thymus mass and 2 courses of chemotherapy. Outcomes: Follow-up data showed that the patient survived 18 months after surgical excision and chemotherapy. Conclusion: The case highlights the importance of screening for malignancy in patients with renal amyloidosis.
第一作者机构:[a]Department of Nephrology and Institute of Nephrology, Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, Chengdu, China,
共同第一作者:
通讯作者:
通讯机构:[a]Department of Nephrology and Institute of Nephrology, Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, Chengdu, China,[*1]Department of Nephrology and Institute of Nephrology, Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, Chengdu, 610072, China
推荐引用方式(GB/T 7714):
Qin Chen,Yongjing Du,Singh Prince,et al.Primary thymic mucosa-associated lymphoid tissue lymphoma complicated with renal amyloidosis A first case report[J].MEDICINE.2020,99(13):doi:10.1097/MD.0000000000019462.
APA:
Qin Chen,Yongjing Du,Singh Prince,Ping Zhang,Guisen Li...&Wei Wang.(2020).Primary thymic mucosa-associated lymphoid tissue lymphoma complicated with renal amyloidosis A first case report.MEDICINE,99,(13)
MLA:
Qin Chen,et al."Primary thymic mucosa-associated lymphoid tissue lymphoma complicated with renal amyloidosis A first case report".MEDICINE 99..13(2020)