机构：[1]Department of Medical Oncology, Fujian Cancer Hospital, FujianMedical University Cancer Hospital, Fuzhou 350014, Fujian, China[2]Cancer Center of the First Hospital of Jilin University,Changchun 130021, Jilin, China[3]Cancer Center, Renmin Hospital of Wuhan University,Wuhan 430060, Hubei, China[4]Department of Gastrointestinal Surgery,Affiliated Tumor Hospital ofGuangxi Medical University, Nanning 530021, Guangxi, China[5]Department of Surgery, The First Affiliated Hospital of Sun Yat-SenUniversity, Guangzhou 510080, Guangdong, China中山大学附属第一医院[6]Department of Clinical Nutrition, West China Hospital of SichuanUniversity, Chengdu 610041, Sichuan, China[7]Department of Gastrointestinal Oncology, National ClinicalResearch Center for Cancer, Tianjin Key Laboratory of CancerPrevention and Therapy, TianjinMedical University Cancer Instituteand Hospital, Tianjin 300060, China[8]Department of Nutrition and Metabolism of Oncology, AffiliatedProvincial Hospital of Anhui Medical University,Hefei 230031, Anhui, China[9]Department of Clinical Nutrition, The First Hospital of HebeiMedical University, Shijiazhuang 050031, Hebei, China[10]Department of Gastrointestinal Surgery, Institute ofGastroenterology, The First Affiliated Hospital of KunmingMedical University, Kunming 650032, Yunnan, China[11]Department of Clinical Nutrition, The First People’s Hospital ofKashi, Xinjiang 844000, China[12]Department of Clinical Nutrition, Chongqing General Hospital,Chongqing 400014, China[13]Department of Colorectal and Anal Surgery, Huizhou MunicipalCentral Hospital, Huizhou 516001, Guangdong, China[14]Department of Radiation and Medical Oncology, ZhongnanHospital of Wuhan University, Wuhan 430071, Hubei, China[15]Department of Oncology, Xingtai People’s Hospital, HebeiMedicalUniversity, Xingtai 054031, Hebei, China[16]The First Department of the Tumor Hospital of Harbin MedicalUniversity, Harbin 150085, Heilongjiang, China[17]Department of Nutrition, Guangdong General Hospital, GuangdongAcademy of Medical Sciences, Guangzhou 510080, Guangdong,China广东省人民医院[18]Department of Oncology, Affiliated Cancer Hospital of ZhengzhouUniversity and Henan Cancer Hospital, Zhengzhou 450008, Henan,China河南省肿瘤医院[19]Department of General Surgery, Xiangya Hospital, Central SouthUniversity, Changsha 410008, Hunan, China[20]Comprehensive Oncology Department, Cancer Hospital, ChineseAcademy of Medical Sciences, Beijing 100021, China[21]Department of Oncology, Affiliated Hospital of Zunyi MedicalUniversity, Zunyi 563000, Guizhou, China[22]The Fourth Affiliated Hospital, Harbin Medical University,Harbin 150001, Heilongjiang, China[23]Cancer Center, The First People’s Hospital of Foshan,Foshan 528000, Guangdong, China[24]Department of Gastrointestinal Tumor Surgery, The First AffiliatedHospital of Xiamen University, Xiamen 361003, Fujian, China[25]Department of Nutrition, Ruijin Hospital, Shanghai Jiao TongUniversity School of Medicine, Shanghai 200025, China[26]Department of Nutrition, Tianjin Third Central Hospital,Tianjin 300170, China[27]Department of Surgery, The First Affiliated Hospital of JinanUniversity, Guangzhou 510632, Guangdong, China[28]Department of General Surgery, Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School,Nanjing 210008, Jiangsu, China[29]Department of Gastrointestinal Surgery, First Affiliated Hospital ofGuangxi Medical University, Nanning 530021, Guangxi, China[30]Department of Radiation and Medical Oncology, People’s Hospitalof Guangxi Zhuang Autonomous Region,Nanning 530021, Guangxi, China[31]Department of Clinical Nutrition, Peking University CancerHospital and Institute, Beijing 100142, China[32]Department of Nutrition, Tumor Hospital of Yunnan Province,Third Affiliated Hospital of Kunming Medical College,Kunming 650118, Yunnan, China[33]Department of Surgery, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan 430030,China华中科技大学同济医学院附属同济医院[34]Department of Nutrition, Guangzhou Red Cross Hospital,Guangzhou 510220, Guangdong, China[35]Department of Radiotherapy, , School of Medicine, Sichuan CancerHospital & Institute, Sichuan Cancer Center, University ofElectronic Science and Technology of China,Chengdu 610041, Sichuan, China四川省肿瘤医院[36]Department of Clinical Nutrition, Clifford Hospital, GuangzhouUniversity of Chinese Medicine, Guangzhou 510632, Guangdong,China[37]Department of Digestive Diseases, Xijing Hospital, FourthMilitaryMedical University, Xi’an 710032, Shanxi, China[38]Department of Hepatobiliary Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences andPeking Union Medical College, Beijing 100021, China[39]Department of Nutrition, Daping Hospital & Research Institute ofSurgery, Third Military Medical University, Chongqing 400042,China[40]Department of Gastrointestinal Surgery/Clinical Nutrition, BeijingShijitan Hospital, Capital Medical University, No.10 Tieyi Road,Haidian District, Beijing 100038, China[41]Department of Epidemiology, College of Public Health, ZhengzhouUniversity, Zhengzhou 450001, Henan, China
Background/objectives The assessment of nutritional status and the quality of life in patients with gastric cancer has become one of the important goals of current clinical treatment. The purpose of this study was to assess the nutritional status in hospitalized gastric cancer patients by using patient-generated subjective global assessment (PG-SGA) and to analyze the influence of nutritional status on the patients' quality of life (QOL). Methods We reviewed the pathological diagnosis of gastric cancer for 2322 hospitalized patients using PG-SGA to assess their nutritional status and collected data on clinical symptoms, the anthropometric parameters (height, weight, body mass index (BMI), mid-arm circumference (MAC), triceps skin-fold thickness (TSF), and hand-grip strength (HGS). We also collected laboratory data (prealbumin, albumin, hemoglobin) within 48 h after the patient was admitted to the hospital. The 30-item European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) was used for QOL assessment in all patients. Results By using PG-SGA, we found 80.4% of the patients were malnourished (score >= 4) and 45.1% of the patients required urgent nutritional support (score >= 9). In univariate analysis, old age (> 65 years, p < 0.001), female (p = 0.007), residence in a village (p = 0.004), a lower level of education (p < 0.001), and self-paying (p < 0.001) were indicated as risk factors of patients with gastric cancer to be suffering from severe malnutrition. There was a negative correlation between PG-SGA and various nutritional parameters (p < 0.05). The quality of life was significantly different in gastric cancer patients with different nutritional status (p < 0.01). Conclusion Malnutrition of hospitalized patients with gastric cancer in China is common and seriously affects the patients' quality of life. The nutritional status should be evaluated in a timely manner and reasonable nutritional intervention should be provided as soon as possible. The PG-SGA was fit for using as a clinical nutrition assessment method, being worthy of clinical application.
基金：
The National Key Research and Development Program [2017YFC1309200]
语种：
外文
高被引：
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2020]版：
大类|2 区医学
小类|2 区康复医学3 区肿瘤学3 区卫生保健与服务
最新[2023]版：
大类|3 区医学
小类|2 区康复医学3 区卫生保健与服务3 区肿瘤学
JCR分区：
出版当年[2020]版：
Q1REHABILITATIONQ2HEALTH CARE SCIENCES & SERVICESQ3ONCOLOGY
最新[2023]版：
Q1REHABILITATIONQ2HEALTH CARE SCIENCES & SERVICESQ2ONCOLOGY
第一作者机构：[1]Department of Medical Oncology, Fujian Cancer Hospital, FujianMedical University Cancer Hospital, Fuzhou 350014, Fujian, China
通讯作者：
推荐引用方式(GB/T 7714)：
Guo Zeng Qing,Yu Jia Mi,Li Wei,et al.Survey and analysis of the nutritional status in hospitalized patients with malignant gastric tumors and its influence on the quality of life[J].SUPPORTIVE CARE IN CANCER.2020,28(1):373-380.doi:10.1007/s00520-019-04803-3.
APA：
Guo, Zeng Qing,Yu, Jia Mi,Li, Wei,Fu, Zhen Ming,Lin, Yuan...&Shi, Han Ping.(2020).Survey and analysis of the nutritional status in hospitalized patients with malignant gastric tumors and its influence on the quality of life.SUPPORTIVE CARE IN CANCER,28,(1)
MLA：
Guo, Zeng Qing,et al."Survey and analysis of the nutritional status in hospitalized patients with malignant gastric tumors and its influence on the quality of life".SUPPORTIVE CARE IN CANCER 28..1(2020):373-380
