Since 2013, highly pathogenic (HP) H5N6 influenza A viruses (IAVs) have emerged in poultry in Asia, especially Southeast Asia. These viruses have also caused sporadic infections in humans within the same geographic areas. Active IAV surveillance in wild birds sampled in Guangdong province, China from August 2014 through February 2015 resulted in the recovery of three H5N6 IAVs. These H5N6 IAV isolates possess the basic amino acid motif at the HA1-HA2 cleavage site that is associated with highly pathogenic IAVs infecting chickens. Noteworthy findings include: (1) the HP H5N6 IAV isolates were recovered from three species of apparently healthy wild birds (most other isolates of HP H5N6 IAV in Asia are recovered from dead wild birds or fecal samples in the environment) and (2) these isolates were apparently the first recoveries of HP H5N6 IAV for two of the three species thus expanding the demonstrated natural host range for these lineages of virus. This investigation provides additional insight into the natural history of HP H5N6 IAVs and identifies the occurrence of non-lethal, HP H5N6 IAV infections in wild birds thereby demonstrating the value of active IAV surveillance in wild birds.
基金：
Science and Technology Projects of Guangdong Province [20140224]; Guangdong Natural Science Funds for Distinguished Young Scholar [2014A030306046]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|3 区综合性期刊
小类|3 区综合性期刊
最新[2023]版：
大类|2 区综合性期刊
小类|2 区综合性期刊
第一作者：
第一作者机构：[1]South China Agr Univ, Coll Vet Med, Guangzhou 510642, Guangdong, Peoples R China;[2]Key Lab Zoonosis Prevent & Control Guangdong Prov, Guangzhou 510642, Guangdong, Peoples R China;[3]Sun Yat Sen Univ, Ctr Canc, Collaborat Innovat Ctr Canc Med, Dept Expt Res,State Key Lab Oncol South China, Guangzhou 510060, Guangdong, Peoples R China;
通讯作者：
通讯机构：[1]South China Agr Univ, Coll Vet Med, Guangzhou 510642, Guangdong, Peoples R China;[2]Key Lab Zoonosis Prevent & Control Guangdong Prov, Guangzhou 510642, Guangdong, Peoples R China;
推荐引用方式(GB/T 7714)：
Kang Yinfeng,Liu Lu,Feng Minsha,et al.Highly pathogenic H5N6 influenza A viruses recovered from wild birds in Guangdong, southern China, 2014-2015[J].SCIENTIFIC REPORTS.2017,7:-.doi:10.1038/srep44410.
APA：
Kang, Yinfeng,Liu, Lu,Feng, Minsha,Yuan, Runyu,Huang, Can...&Ren, Tao.(2017).Highly pathogenic H5N6 influenza A viruses recovered from wild birds in Guangdong, southern China, 2014-2015.SCIENTIFIC REPORTS,7,
MLA：
Kang, Yinfeng,et al."Highly pathogenic H5N6 influenza A viruses recovered from wild birds in Guangdong, southern China, 2014-2015".SCIENTIFIC REPORTS 7.(2017):-
