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Application of single-cell technology in cancer research

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收录情况： ◇ EI

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机构： [a]State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China [b]Department of Radiation Oncology, Cancer Center, First People's Hospital of Foshan Affiliated to Sun Yat-sen University, Foshan 528000, China

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关键词： Individualized treatment Intratumor heterogeneity Rare tumor cells Single-cell technology Tumor epigenetics

摘要：

In this review, we have outlined the application of single-cell technology in cancer research. Single-cell technology has made encouraging progress in recent years and now provides the means to detect rare cancer cells such as circulating tumor cells and cancer stem cells. We reveal how this technology has advanced the analysis of intratumor heterogeneity and tumor epigenetics, and guided individualized treatment strategies. The future prospects now are to bring single-cell technology into the clinical arena. We believe that the clinical application of single-cell technology will be beneficial in cancer diagnostics and treatment, and ultimately improve survival in cancer patients. © 2017 The Authors

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出版当年[2017]版中科院分区表Review为是的期刊

：

大类 | 1 区

工程技术

小类 | 1 区生物工程与应用微生物

最新[2023]版

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大类 | 1 区

工程技术

小类 | 1 区生物工程与应用微生物

第一作者：

第一作者机构： [a]State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China [b]Department of Radiation Oncology, Cancer Center, First People's Hospital of Foshan Affiliated to Sun Yat-sen University, Foshan 528000, China

通讯作者：

通讯机构： [a]State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China

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