详情页 - 四川省肿瘤医院知识库

当前位置：首页 > 详情页

Application of single-cell technology in cancer research

文献详情

资源类型：

收录情况： ◇ EI

作者：

机构： [a]State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China [b]Department of Radiation Oncology, Cancer Center, First People's Hospital of Foshan Affiliated to Sun Yat-sen University, Foshan 528000, China

出处：

DOI：

ISSN：

关键词： Individualized treatment Intratumor heterogeneity Rare tumor cells Single-cell technology Tumor epigenetics

摘要：

In this review, we have outlined the application of single-cell technology in cancer research. Single-cell technology has made encouraging progress in recent years and now provides the means to detect rare cancer cells such as circulating tumor cells and cancer stem cells. We reveal how this technology has advanced the analysis of intratumor heterogeneity and tumor epigenetics, and guided individualized treatment strategies. The future prospects now are to bring single-cell technology into the clinical arena. We believe that the clinical application of single-cell technology will be beneficial in cancer diagnostics and treatment, and ultimately improve survival in cancer patients. © 2017 The Authors

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2017]版中科院分区表Review为是的期刊

：

大类 | 1 区

工程技术

小类 | 1 区生物工程与应用微生物

最新[2023]版

：

大类 | 1 区

工程技术

小类 | 1 区生物工程与应用微生物

第一作者：

第一作者机构： [a]State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China [b]Department of Radiation Oncology, Cancer Center, First People's Hospital of Foshan Affiliated to Sun Yat-sen University, Foshan 528000, China

通讯作者：

通讯机构： [a]State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Single-cell RNA sequencing highlights intratumor heterogeneity and intercellular network featured in adamantinomatous craniopharyngioma [2]Intratumor Heterogeneity of MIF Expression Correlates With Extramedullary Involvement of Multiple Myeloma. [3]Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma [4]The characteristics of breast cancer subtypes: implications for treatment guidelines and individualized treatment strategies in China. [5]bITH, a blood-based metric of intratumor heterogeneity, is associated with clinical response to immune checkpoint blockade in non-small cell lung cancer [6]bITH, a blood-based metric of intratumor heterogeneity, is associated with clinical response to immune checkpoint blockade in non-small cell lung cancer [7]Comprehensive analysis of necroptotic patterns and associated immune landscapes in individualized treatment of skin cutaneous melanoma [8]Application of Inflatable Video-Assisted Mediastinoscopic Transhiatal Esophagectomy in Individualized Treatment of Esophageal Cancer [9]肿瘤标志物与癌症的个体化治疗 [10]Values of circulating tumor DNA for non-small cell lung cancer patients receiving neoadjuvant therapy, progress and challenges: a narrative review