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Influence of occupation and education level on breast cancer stage at diagnosis, and treatment options in China A nationwide, multicenter 10-year epidemiological study

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机构: [a]Department of Breast Surgery, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, [b]Department of Cancer Epidemiology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, [c]Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, [d]Department of Breast Surgery, Zhejiang Cancer Hospital, Hangzhou, [e]Department of Breast Oncology, Sun Yat- Sen University Cancer Center, Guangzhou, [f]Department of Breast-thyroid Surgery, Xiangya Second Hospital, Central South University, Changsha, [g]Department of Breast Surgery, Liaoning Cancer Hospital, Shenyang, [h]Center of Breast Disease, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, [i]Department of Pathology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China
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关键词: breast cancer clinical and pathological characteristics education level occupation TNM staging treatment patterns

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The objective of this study was to evaluate the impact of occupation and education level of Chinese female breast cancer patients on their cancer staging at diagnosis, clinical and pathological features, rate of implementation, and selection of treatment. The medical charts of 4211 confirmed female breast cancer cases diagnosed between 1999 and 2008, from 7 breast cancer centers spread across the whole of China, were reviewed. Data including information on the patient's sociodemographic status, clinical and pathological characteristics, implementation of clinical examination and treatment modalities were analyzed. In parallel, the associations between different occupations and level of educational attainment were analyzed in relation to tumor stage through TNM staging, clinical and pathological characteristics, implementation of clinical examination, and treatment patterns. Multivariate logistic regression was used to identify whether the occupation and education level of patients are independent factors of TNM staging at diagnosis. There were significant differences among different occupation groups and the education level of patients in regards to pathological characteristics and treatment choice. Both the occupation and education level of patients were independent factors of TNM staging at diagnosis. For patients within the lower-income occupation or lower educational attainment group, the tumor stage waslater, the rates of implementation of relevant investigations were lower, as were the rates of radiotherapy, chemotherapy, and endocrine therapy. This study suggests that strategies should work toward developing more accurate and effective breast cancer prevention and treatment strategies aimed specifically at patients with lower educational attainment levels and at specific occupation groups.

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出版当年[2017]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 医学:内科
第一作者:
第一作者机构: [a]Department of Breast Surgery, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an,
通讯作者:
通讯机构: [a]Department of Breast Surgery, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, [*1]Department of Breast Surgery, the First Affiliated Hospital of Xi’an Jiaotong University, No. 277, West Yanta Road, Xi’an 710061, Shaanxi Province, China
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