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Sequential Chemo-Immunotherapy as a Novel Bridging Strategy for Non-Complete Responders after Neoadjuvant Chemoradiotherapy in Esophageal Cancer: First Prospective Phase 2 Trial Challenging Immediate Surgery Paradigm

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机构: [1]Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Dept Radiat Oncol,Sch Med,Sichuan Canc Ctr, Radiat Oncol Key Lab Sichuan Prov, Chengdu, Peoples R China [2]Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Sichuan Canc Ctr, Dept Thorac Surg,Sch Med, Chengdu, Peoples R China [3]Univ Elect Sci & Technol China, Sichuan Hosp Canc & Inst, Sichuan Clin Res Ctr Canc, Sichuan Canc Ctr, Chengdu, Peoples R China [4]Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst,Dept Radiat Oncol, Sichuan Clin Res Ctr Canc,Sichuan Canc Ctr, Radiat Oncol Key Lab Sichuan Prov, Chengdu, Peoples R China
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Purpose/Objective(s): Non-clinical complete responders (non-CCR) after neoadjuvant chemoradiotherapy (NCRT) for locally advanced esophageal squamous cell carcinoma (LA-ESCC) face high recurrence risks with immediate surgery. This first study evaluates the efficacy and safety of sequential chemo-immunotherapy (SCI) as a bridge to surgery in this population.

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出版当年[2025]版:
大类 | 1 区 医学
小类 | 2 区 肿瘤学 2 区 核医学
最新[2025]版:
大类 | 1 区 医学
小类 | 2 区 肿瘤学 2 区 核医学
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出版当年[2024]版:
Q1 ONCOLOGY Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2024]版:
Q1 ONCOLOGY Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

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第一作者机构: [1]Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Dept Radiat Oncol,Sch Med,Sichuan Canc Ctr, Radiat Oncol Key Lab Sichuan Prov, Chengdu, Peoples R China
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