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A Multi-Dimensional Deep Ensemble Learning Model Predicts Pathological Response and Treatment Outcomes to Neoadjuvant Chemoradiotherapy in Esophageal Squamous Cell Carcinoma Using Pretreatment CT Images: A Multicenter, Retrospective Cohort Study

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机构: [1]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Radiat Oncol, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China [2]Wenzhou Med Univ, Sch Biomed Engn, Wenzhou, Peoples R China [3]Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Sichuan Clin Res Ctr Canc, Sichuan Canc Ctr,Dept Thorac Surg, Chengdu, Peoples R China [4]Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Tianjins Clin Res Ctr Canc, Key Lab Canc Prevent & Therapy, Tianjin, Peoples R China [5]Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Tianjins Clin Res Ctr Canc, Dept Radiat Oncol, Tianjin, Peoples R China [6]Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Sch Med, Dept Radiat Oncol, Shanghai, Peoples R China [7]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Natl Clin Res Ctr Canc, Dept VIP Med Serv,Canc Hosp, Beijing, Peoples R China [8]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Diagnost Radiol, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China [9]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Thorac Surg, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China [10]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Pathol, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China [11]Univ Elect Sci Technol China, Sichuan Canc Hosp & Inst, Sichuan Canc Ctr, Sch Med,Dept Radiat Oncol, Chengdu, Peoples R China
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摘要:
Purpose/Objective(s): Neoadjuvant chemoradiotherapy (nCRT) followed by esophagectomy is the standard treatment for esophageal squamous cell carcinoma (ESCC). However, accurate prediction of pathological complete response (pCR) and treatment outcome remains a major clinical challenge. This study aimed to develop and validate a multidimensional deep ensemble learning model (DELRN) using pretreatment CT imaging to predict pCR and stratify prognostic risk for ESCC patients undergoing nCRT.

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出版当年[2025]版:
大类 | 1 区 医学
小类 | 2 区 肿瘤学 2 区 核医学
最新[2025]版:
大类 | 1 区 医学
小类 | 2 区 肿瘤学 2 区 核医学
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出版当年[2024]版:
Q1 ONCOLOGY Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2024]版:
Q1 ONCOLOGY Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2024版] 最新五年平均 出版当年[2024版] 出版当年五年平均 出版前一年[2024版]

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第一作者机构: [1]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Radiat Oncol, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China
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