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Longitudinal Trajectories of Adiposity Indicators and Cancer Risk Over 14 Years: Evidence from Repeated Health Check-Ups of 10 Times or More - China, 2010-2023

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收录情况： ◇ 统计源期刊 ◇ CSCD-C ◇ 卓越：梯队期刊

作者：

机构： [1]Department of Urology, Innovation Institute for Integration of Medicine and Engineering, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, China. [2]Department of Urology, Lab of Health Data Science, West China Hospital, Key Laboratory of Bio-Resource and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu City, Sichuan Province, China. [3]Department of Urology, Lab of Health Data Science, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, China. [4]Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [5]Sichuan Public Health General Clinical Center, Chengdu, Sichuan Province, China.

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摘要：

Central obesity is a recognized risk factor for several types of cancers. However, most supporting evidence originates from Western populations and relies on single adiposity measurements, with limited longitudinal data available from China.Drawing on data from more than 25,000 Chinese adults who each underwent 10 or more health check-ups over 14 years, this study demonstrated that waist-related indicators - particularly Body Mass Index -adjusted waist circumference (WCadjBMI) and waist-to-hip ratio (WHRadjBMI) - and their inverted U-shaped trajectories are more strongly associated with cancer risk than BMI alone, especially in men and adults aged 50 years and above.Tracking changes in waist-related fat measures over time may help identify cancer risk earlier than BMI monitoring alone. Integrating central obesity measures into routine screening could improve targeted cancer prevention, particularly for the older and male populations, and advance the goals of Healthy China 2030.Copyright © 2025 by Chinese Center for Disease Control and Prevention.

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出版当年[2025]版：

大类 | 4 区医学

小类 | 4 区公共卫生、环境卫生与职业卫生

最新[2025]版：

大类 | 4 区医学

小类 | 4 区公共卫生、环境卫生与职业卫生

第一作者：

第一作者机构： [1]Department of Urology, Innovation Institute for Integration of Medicine and Engineering, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, China.

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通讯作者：

通讯机构： [1]Department of Urology, Innovation Institute for Integration of Medicine and Engineering, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, China. [3]Department of Urology, Lab of Health Data Science, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, China. [4]Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [5]Sichuan Public Health General Clinical Center, Chengdu, Sichuan Province, China.

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