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Tumor Type, Fusion Partner, and IHC Staining Patterns of 145 Solid Tumor Samples with NTRK3 Fusion: A Chinese Multicenter Retrospective Cross-Sectional Study

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收录情况： ◇ SCIE ◇ CPCI(ISTP)

作者：
Wu, Shafei[1] * ; Han, Yuchen[2] ; Zhang, Zhihong[3] ; Chen, Gang[4] ; Wang, Jian[5] ; Yang, Wentao[5] ; Meng, Bin[6] ; Sun, Yan[6] ; Liu, Yang[7] ; Li, Wencai[8] ; Li, Shenglei[8] ; Wang, Lifeng[9] ; Zhang, Hongying[10] ; Guo, Lingchuan[11] ; Liu, Yueping[12] ; Liu, Xiao-Ding[1] ; Hong, Ruping[13] ; Li, Kaimi[1] ; Liang, Zhiyong[1] ;
机构： [1]Peking Union Med Coll Hosp, Beijing, Peoples R China [2]Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Shanghai, Peoples R China [3]Jiangsu Prov Hosp, Nanjing, Peoples R China [4]Fujian Canc Hosp, Fuzhou, Peoples R China [5]Fudan Univ, Shanghai Canc Ctr, Shanghai, Peoples R China [6]Tianjin Med Univ, Canc Inst & Hosp, Tianjin, Peoples R China [7]Sichuan Canc Hosp, Chengdu, Peoples R China [8]Zhengzhou Univ, Affiliated Hosp 1, Zhengzhou, Peoples R China [9]Shanghai Jiao Tong Univ, Xin Hua Hosp, Sch Med, Shanghai, Peoples R China [10]Sichuan Univ, West China Hosp, Chengdu, Peoples R China [11]Soochow Univ, Affiliated Hosp 1, Suzhou, Peoples R China [12]Hebei Med Univ, Hosp 4, Shijiazhuang, Peoples R China [13]Chinese Acad Med Sci, Peking Union Med Coll, Peking Union Med Coll Hosp, Beijing, Peoples R China
出处：
DOI： 10.1016/j.labinv.2024.103417
ISSN：

摘要：
Background: The ESMO guidelines recommend using immunohistochemistry (IHC) as a screening method to select cases for additional next-generation sequencing (NGS) testing to detect neurotrophic tyrosine receptor kinase (NTRK) fusions. NTRK3 fusion, the most common fusion accounting for 60-80% of NTRK+ samples, warrants a comprehensive understanding of its tumor types, fusion partners, and IHC staining patterns to improve patient selection for targeted therapies.

语种：
外文
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中科院(CAS)分区：
出版当年[2025]版：
大类 | 2 区 医学
小类 | 2 区 医学：研究与实验 2 区 病理学
最新[2025]版：
大类 | 2 区 医学
小类 | 2 区 医学：研究与实验 2 区 病理学
JCR分区：
出版当年[2024]版：
Q1 PATHOLOGY Q2 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2024]版：
Q1 PATHOLOGY Q2 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子： 最新[2024版] 最新五年平均 出版当年[2024版] 出版当年五年平均 出版前一年[2024版]

第一作者：
第一作者机构： [1]Peking Union Med Coll Hosp, Beijing, Peoples R China
推荐引用方式(GB/T 7714)：
Wu Shafei,Han Yuchen,Zhang Zhihong,et al.Tumor Type, Fusion Partner, and IHC Staining Patterns of 145 Solid Tumor Samples with NTRK3 Fusion: A Chinese Multicenter Retrospective Cross-Sectional Study[J].LABORATORY INVESTIGATION.2025,105(3):51-52.doi:10.1016/j.labinv.2024.103417.
APA：
Wu, Shafei,Han, Yuchen,Zhang, Zhihong,Chen, Gang,Wang, Jian...&Liang, Zhiyong.(2025).Tumor Type, Fusion Partner, and IHC Staining Patterns of 145 Solid Tumor Samples with NTRK3 Fusion: A Chinese Multicenter Retrospective Cross-Sectional Study.LABORATORY INVESTIGATION,105,(3)
MLA：
Wu, Shafei,et al."Tumor Type, Fusion Partner, and IHC Staining Patterns of 145 Solid Tumor Samples with NTRK3 Fusion: A Chinese Multicenter Retrospective Cross-Sectional Study".LABORATORY INVESTIGATION 105..3(2025):51-52

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