详情页 - 四川省肿瘤医院知识库

当前位置：首页 > 详情页

Unlocking the Potential of Extracellular Vesicles in Cardiovascular Disease

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China. [2]Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, China.

出处：

DOI：

ISSN：

关键词： CVD EVs exosomes microparticles

摘要：

Extracellular vesicles (EVs) are micro-nanoscale biological particles encapsulated by phospholipid bilayers, which regulate cell migration, angiogenesis and tumour cell growth by transmitting various biomolecules such as nucleic acids and proteins. EVs are composed of exosomes, microparticles and apoptotic bodies. Its benefits pass through biofilms and are not degraded by various enzymes, so it can be used as a biomarker in potential diseases and has attracted much attention from researchers. Current studies have found that EVs are involved in the development of various cardiovascular diseases (CVD), such as heart failure and myocardial ischemia-reperfusion injury. In addition, stem cell-derived EVs play an important role in the diagnosis and treatment of a variety of CVD. In this review, we present the biological features of EVs, the role of EVs in various CVD, and the challenges they encounter in the treatment of CVD.© 2025 The Author(s). Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

基金：

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2025]版：

无

最新[2023]版：

大类 | 2 区

医学

小类 | 2 区医学：研究与实验 3 区细胞生物学

第一作者：

第一作者机构： [1]Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China. [2]Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, China.

共同第一作者：

通讯作者：

通讯机构： [1]Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China. [2]Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Role of Extracellular Vesicles on Cancer Lymphangiogenesis and Lymph Node Metastasis [2]Advanced application of carbohydrate-based micro/nanoparticles for rheumatoid arthritis [3]Exosomes: a promising avenue for cancer diagnosis beyond treatment [4]Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells [5]Exploring exosomes: novel diagnostic and therapeutic frontiers in thyroid cancer [6]CVD phenotyping in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology [7]外泌体作为药物传递系统的前景及挑战 [8]Plant-derived exosomes in therapeutic nanomedicine, paving the path toward precision medicine [9]Exosomes in sarcoma: Prospects for clinical applications [10]Total, dietary, and supplemental calcium intake and risk of all-cause, cardiovascular, and cancer mortality among US adults: a prospective cohort study from the National Health and Nutrition Examination Survey