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The clinical target volume delineation based on the correlation analysis of neck node levels in oral cavity squamous cell carcinoma (OCSCC)

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机构： [1]Department of Oncology, The General Hospital of Western Theater Command, Chengdu, China [2]Department of Oncology, The Afliated Hospital of Southwest Medical University, Luzhou, China [3]Department of Oncology, The First Afliated Hospital of Chengdu Medical College, Chengdu, China [4]Department of Nuclear Medicine, The General Hospital of Western Theater Command, Chengdu, China [5]Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan, Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute,. Sichuan Cancer Center, Afliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China

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关键词： Oral cavity squamous cell carcinoma Neck node levels Lymph node metastasis Correlation analysis

摘要：

The delineation of clinical target volume (CTV) base on the correlation analysis between neck node levels of OCSCC has not been reported in detail. This study analyzes the correlations between the neck node levels in 208 cases of OCSCC, and aims to provide preliminary reference for the CTV delineation in OCSCC patients.The records of 208 OCSCC patients were retrospectively analyzed. The neck node levels were evaluated according to the 2013 updated guidelines. The Chi-square test and logistic regression model were used to analyze the correlation of each level.The most common involved level in OCSCC is Ib (45.7%) and IIa (40.4%). Correlation analysis of OCSCC showed that nodal spread in level Ia is related to levels Ib and VIa. Level Ib is related to levels Ia, IIa, IX. Level IIa is related to levels Ib, IIb, III. Level IIb is related to levels IIa, III, Va. Level III is related to levels IIa, IIb, Va. Level Va is related to levels IIb and III. Level VIa is related to level Ia and T stage. Level IX is only related to level Ib. T stage is only related to level VIa. All the above P values are < 0.05.The related levels can be considered as high-risk region (HRR) and the unrelated levels as low-risk region (LRR) in the radiotherapy of OCSCC patients. This study can make the CTV delineation more individualized and accurate.© 2024. The Author(s).

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大类 | 2 区

医学

小类 | 3 区肿瘤学

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出版当年[2024]版：

无

最新[2023]版：

Q2 ONCOLOGY

影响因子： 3.4 最新[2023版] 3.8 最新五年平均 3.4 出版当年[2023版] 0 出版当年五年平均 3.4 出版前一年[2023版]

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第一作者机构： [1]Department of Oncology, The General Hospital of Western Theater Command, Chengdu, China

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