机构：[1]Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China四川大学华西医院[2]Department of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China[3]Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China四川大学华西医院[4]Department of Gastroenterology and Laboratory of Inflammatory Bowel Disease, the Center for Inflammatory Bowel Disease, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China四川大学华西医院
The cohort study conducted by Yu et al.,1 which utilized data from Norwegian and Swedish populations, captured our attention with its intriguing findings. The study revealed an eightfold increased risk of small bowel adenocarcinoma in patients diagnosed with Crohn’s disease (CD), a twofold increased risk of small bowel adenocarcinoma in patients diagnosed with ulcerative colitis (UC), and a twofold increased risk of neuroendocrine tumors in patients diagnosed with both CD and UC. However, because of the relatively low absolute excess risk associated with developing small bowel cancer, implementing early surveillance measures may not be cost-effective. The assessment of causality in observational studies is often challenging because of the presence of multiple confounding factors. The existence of a causal relationship between inflammatory bowel disease and small bowel malignancy remains unclear at present.
基金：
National Natural Science
Foundation of China [grant number 82070560] and 1.3.5
Project for Disiplines of Excellence, West China Hospital,
Sichuan University [grant number ZYGD23013]
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2024]版：
无
最新[2023]版：
大类|1 区医学
小类|1 区肿瘤学
第一作者：
第一作者机构：[1]Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University, Chengdu, China[2]Department of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China
通讯作者：
通讯机构：[3]Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China[4]Department of Gastroenterology and Laboratory of Inflammatory Bowel Disease, the Center for Inflammatory Bowel Disease, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China
推荐引用方式(GB/T 7714)：
Luo X J,An H J,Gan H T.Inflammatory bowel disease and risk of malignant neoplasm in the small bowel[J].Annals Of Oncology : Official Journal Of The European Society For Medical Oncology.2024,35(4):402-404.doi:10.1016/j.annonc.2023.12.012.
APA：
Luo X J,An H J&Gan H T.(2024).Inflammatory bowel disease and risk of malignant neoplasm in the small bowel.Annals Of Oncology : Official Journal Of The European Society For Medical Oncology,35,(4)
MLA：
Luo X J,et al."Inflammatory bowel disease and risk of malignant neoplasm in the small bowel".Annals Of Oncology : Official Journal Of The European Society For Medical Oncology 35..4(2024):402-404
医学