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Consensus on clinical diagnosis and medical treatment of HER2-low breast cancer (2022 edition)

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收录情况: ◇ ESCI

机构: [1]Sichuan Univ, West China Hosp, Dept Pathol, Chengdu, Peoples R China [2]Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Natl Clin Res Ctr Canc, Dept Internal Med,Canc Hosp, Beijing, Peoples R China [3]Peking Univ Canc Hosp & Inst, Breast Canc Prevent & Treatment Ctr, Minist Educ Beijing, Key Lab Carcinogenesis & Translat Res, Beijing, Peoples R China [4]Fudan Univ, Shanghai Canc Ctr, Dept Oncol, Shanghai, Peoples R China [5]Second Hosp Dalian Med Univ, Dept Cardiology2, Dalian, Peoples R China [6]Guangdong Prov Peoples Hosp, Dept Breast Canc, Ctr Canc, Guangzhou, Peoples R China [7]Sichuan Univ, West China Hosp, Breast Dis Ctr, Chengdu, Peoples R China [8]Kunming Med Univ, Yunnan Canc Hosp, Dept Breast Surg, Affiliated Hosp 3, Kunming, Peoples R China [9]First Affiliated Hosp USTC, Anhui Prov Hosp, Dept Hematol, Hefei 230001, Peoples R China [10]Chongqing Gen Hosp, Dept Breast & Thyroid Surg, Chongqing, Peoples R China [11]Fudan Univ, Shanghai Canc Ctr, Dept Breast Surg, Shanghai, Peoples R China [12]Peking Univ Canc Hosp & Inst, Dept Breast Oncol, Minist Educ Beijing, Key Lab Carcinogenesis & Translat Res, Beijing, Peoples R China [13]Liaoning Canc Hosp & Inst, Dept Breast Surg, Shenyang 110042, Liaoning, Peoples R China [14]First Hosp China Med Univ, Dept Radiol, Shenyang, Peoples R China [15]Tianjin Med Univ Canc Inst & Hosp, Dept Breast Med, Tianjin, Peoples R China [16]Sun Yat Sen Univ, Canc Ctr, Dept Hematol Oncol, Guangzhou, Peoples R China [17]Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Natl Canc Ctr, Dept VIP Med Serv,Canc Hosp, Beijing, Peoples R China [18]Shandong Canc Hosp, Breast Canc Ctr, Jinan, Shandong, Peoples R China [19]Chinese Acad Med Sci & Peking Union Med Coll, Clin Trial Ctr, Natl Canc Ctr, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China [20]Peking Univ First Hosp, Breast Dis Ctr, Beijing, Peoples R China [21]Xian Int Med Ctr Hosp, Dept Oncol, Xian, Peoples R China [22]Fudan Univ, Shanghai Canc Ctr, Dept Pathol, Shanghai, Peoples R China [23]Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Oncol, Guangzhou, Peoples R China [24]Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Natl Canc Ctr, Dept Pathol,Canc Hosp, Beijing, Peoples R China [25]Harbin Med Univ, Canc Hosp, Dept Oncol, Harbin, Peoples R China [26]Beijing Hosp, Dept Pathol, Beijing, Peoples R China [27]Qinghai Univ, Breast Dis Diag & Treatment Ctr, Affiliated Hosp, Xining 810000, Peoples R China
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关键词: Breast cancer HER2-low Antibody -drug conjugate

摘要:
Treatment of breast cancer with low expression of human epidermal growth factor receptor 2 (HER2; HER2low) has drawn much attention in recent years. With the proven therapeutic effect of trastuzumab deruxtecan (T-DXd) in patients with HER2-low (immunohistochemistry [IHC] 1 + , or IHC2 + /in situ hybridization [ISH]-) breast cancer, HER2-low may become a new subtype of targeted therapy for breast cancer. The expert committee formulated this consensus based on the current clinical studies and clinical medication experience. The currentconsensus is the collaborative work of an interdisciplinary working group, including experts in the fields of pathology and oncology. The purpose of this consensus was to guide the clinical diagnosis and treatment of HER2-low breast cancer, thereby prolonging the overall survival of patients.

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出版当年[2023]版:
Q1 ONCOLOGY
最新[2023]版:
Q1 ONCOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

第一作者:
第一作者机构: [1]Sichuan Univ, West China Hosp, Dept Pathol, Chengdu, Peoples R China
通讯作者:
通讯机构: [1]Sichuan Univ, West China Hosp, Dept Pathol, Chengdu, Peoples R China [19]Chinese Acad Med Sci & Peking Union Med Coll, Clin Trial Ctr, Natl Canc Ctr, Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China
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