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The role of long non-coding RNAs in the development of adipose cells

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机构： [1]Educational and Scientific Institute of Neurosurgery, Рeoples’ Friendship University of Russia (RUDN University), Moscow, Russia [2]Department of Neurosurgery, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia [3]Department of Obstetrics and Gynecology, Tyumen State Medical University, 54 Odesskaya Street, 625023, Tyumen, Russia [4]Gastric Cancer Center, West China Hospital of Sichuan University, China [5]Department of Internal Diseases, Bashkir State Medical University, Ufa, Republic of Bashkortostan, 450008, Russia [6]Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China [7]City Clinical Hospital 𝒩◦21, Ufa, Republic of Bashkortostan, 450071, Russia [8]Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science, Tomsk, Russia

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In recent times, the rising prevalence of obesity and its associated comorbidities have had a severe impact on human health and social progress. Therefore, scientists are delving deeper into the pathogenesis of obesity, exploring the role of non-coding RNAs. Long non-coding RNAs (lncRNAs), once regarded as mere "noise" during genome transcription, have now been confirmed through numerous studies to regulate gene expression and contribute to the occurrence and progression of several human diseases. LncRNAs can interact with protein, DNA, and RNA, respectively, and participate in regulating gene expression by modulating the levels of visible modification, transcription, post-transcription, and biological environment. Increasingly, researchers have established the involvement of lncRNAs in regulating adipogenesis, development, and energy metabolism of adipose tissue (white and brown fat). In this article, we present a literature review of the role of lncRNAs in the development of adipose cells.© 2023 The Authors.

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出版当年[2023]版：

大类 | 3 区生物学

小类 | 3 区生化与分子生物学

最新[2023]版：

大类 | 3 区生物学

小类 | 3 区生化与分子生物学

第一作者：

第一作者机构： [1]Educational and Scientific Institute of Neurosurgery, Рeoples’ Friendship University of Russia (RUDN University), Moscow, Russia [2]Department of Neurosurgery, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia

通讯作者：

通讯机构： [1]Educational and Scientific Institute of Neurosurgery, Рeoples’ Friendship University of Russia (RUDN University), Moscow, Russia [*1]Рeoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation

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