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Investigations into the impact of non-coding RNA on the sensitivity of gastric cancer to radiotherapy

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机构： [1]Department of Medical Imaging, Central Hospital Affiliated to Chongqing University of Technology, Chongqing, China, [2]Department of Obstetrics and Gynecology, Tyumen State Medical University, Tyumen, Russia, [3]Department of Neurosurgery, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia, [4]Department of Internal Diseases, Bashkir State Medical University, Ufa, Russia, [5]Gastric Cancer Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China, [6]Department of Oncology and Radiology, Ural State Medical University, Yekaterinburg, Russia, [7]Department of Clinical Pharmacology, Smolensk State Medical University, Smolensk, Russia, [8]Educational and Scientific Institute of Neurosurgery, Reoples’ Friendship University of Russia (RUDN University), Moscow, Russia

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Non-coding RNAs (ncRNAs) are a newly discovered functional RNA different from messenger RNA, which can participate in regulating the occurrence and development of tumors. More and more research results show that ncRNAs can participate in the regulation of gastric cancer (GC) radiotherapy response, and its mechanism may be related to its effect on DNA damage repair, gastric cancer cell stemness, cell apoptosis, activation of epidermal growth factor receptor signaling pathway, etc. This article summarizes the relevant mechanisms of ncRNAs regulating the response to radiotherapy in gastric cancer, which will be directly important for the introduction of ncRNAs particularly microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) into clinical medicine as biomarkers and therapeutic targets.Copyright © 2023 Usman, Beilerli, Sufianov, Kudryashov, Ilyasova, Balaev, Danilov, Lu and Gareev.

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出版当年[2023]版：

大类 | 3 区医学

小类 | 3 区生理学

最新[2025]版：

大类 | 3 区医学

小类 | 2 区生理学

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第一作者机构： [1]Department of Medical Imaging, Central Hospital Affiliated to Chongqing University of Technology, Chongqing, China,

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