机构：[1]Departments of Spine Surgery, Shengjing Hospital of China Medical University, Shenyang, China,中国医科大学附属盛京医院中国医科大学盛京医院[2]Department of Tissue Engineering, China Medical University, Shenyang, China,[3]Departments of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China,中国医科大学附属盛京医院中国医科大学盛京医院[4]NMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial and Institute of Regulatory Science for Medical Device and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China
The repair and reconstruction of bone defects and the inhibition of local tumor recurrence are two common problems in bone surgery. The rapid development of biomedicine, clinical medicine, and material science has promoted the research and development of synthetic degradable polymer anti-tumor bone repair materials. Compared with natural polymer materials, synthetic polymer materials have machinable mechanical properties, highly controllable degradation properties, and uniform structure, which has attracted more attention from researchers. In addition, adopting new technologies is an effective strategy for developing new bone repair materials. The application of nanotechnology, 3D printing technology, and genetic engineering technology is beneficial to modify the performance of materials. Photothermal therapy, magnetothermal therapy, and anti-tumor drug delivery may provide new directions for the research and development of anti-tumor bone repair materials. This review focuses on recent advances in synthetic biodegradable polymer bone repair materials and their antitumor properties.
基金：
Sichuan Science and Technology Program [2020YFH0008]; National Key R&D Program of China [2017YFA0105802]
第一作者机构：[1]Departments of Spine Surgery, Shengjing Hospital of China Medical University, Shenyang, China,[2]Department of Tissue Engineering, China Medical University, Shenyang, China,
通讯作者：
通讯机构：[2]Department of Tissue Engineering, China Medical University, Shenyang, China,[4]NMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial and Institute of Regulatory Science for Medical Device and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China
推荐引用方式(GB/T 7714)：
Yu Honghao,Liu Haifeng,Shen Yuan,et al.Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects[J].FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY.2023,11:doi:10.3389/fbioe.2023.1096525.
APA：
Yu, Honghao,Liu, Haifeng,Shen, Yuan&Ao, Qiang.(2023).Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,11,
MLA：
Yu, Honghao,et al."Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 11.(2023)
