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Role of 68Ga-FAPI-04 PET/CT in the Initial Staging of Esophageal Cancer

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机构: [1]Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [2]Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [3]Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [4]Institute of Nuclear Medicine, Southwest Medical University, Luzhou, China. [5]Department of Nuclear Medicine, The Yibin No. 2 People's Hospital, Yibin, China. [6]Department of Thoracic Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
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To investigate the clinical value of 68Ga-FAPI-04 PET/CT for initial staging of esophageal cancer.A total of 44 newly diagnosed patients with esophageal cancer were included in the analysis on the basis of postoperative pathology or clinical and radiologic follow-up.All primary lesions showed increased 68Ga-FAPI-04 uptake, with an SUVmax of 14.92 ± 6.91. A total of 561 lymph nodes were verified by surgery (507) or clinical and radiologic follow-up (54), of which 92 lymph nodes were diagnosed as showing metastases. Seventy-five lymph nodes with metastases showed positive findings on 68Ga-FAPI-04, with a diameter of about 1.06 ± 0.53 cm and SUVmax of 8.10±4.71. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for lymph node metastasis detection were 81.5%, 99.3%, 96.6%, 96.2%, and 96.5%, respectively.68Ga-FAPI-04 PET/CT showed good diagnostic performance in detecting lymph node metastases of esophageal cancer.Thieme. All rights reserved.

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出版当年[2023]版:
大类 | 4 区 医学
小类 | 4 区 核医学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 核医学
第一作者:
第一作者机构: [1]Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [2]Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [3]Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [4]Institute of Nuclear Medicine, Southwest Medical University, Luzhou, China.
通讯作者:
通讯机构: [1]Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [2]Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [3]Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China. [4]Institute of Nuclear Medicine, Southwest Medical University, Luzhou, China. [*1]Department of Nuclear Medicine The Affiliated Hospital of Southwest Medical University, Luzhou, China
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