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The efficacy of high-flow oxygen versus conventional oxygen for asthma control: a meta-analysis of randomized controlled studies

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机构： [1]Department of Gastroenterology, Suining First People's Hospital, Suining, Sichuan, China. [2]The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou, Sichuan, China. [3]Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital and Chongqing Cancer Institute and Chongqing Cancer Hospital, Chongqing, China. [4]Department of Thoracic Surgery, Suining Central Hospital, Suining, Sichuan, China.

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The efficacy of high-flow oxygen versus conventional oxygen therapy for asthma control remains controversial.This meta-analysis aims to explore the influence of high-flow oxygen versus conventional oxygen therapy on asthma control.We have searched PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases, and included randomized controlled trials (RCTs) assessing the efficacy of high-flow oxygen versus conventional oxygen therapy for asthma control.Four RCTs are included in this meta-analysis. Overall, compared with conventional oxygen therapy for asthma, high-flow oxygen is associated with a significantly lower dyspnoea score (standard mean difference (SMD) = -0.63; 95% confidence interval (CI): -1.08 to -0.17; p = 0.008), but reveals no remarkable influence on PaCO2 (SMD = 0.28; 95% CI: -0.22 to 0.77; p = 0.28), PaO2 (SMD = 0.44; 95% CI: -1.34 to 2.22; p = 0.63), intubation rate (OR = 1.09; 95% CI: 0.15 to 8.21; p = 0.93) or hospital length of stay (SMD = -0.07; 95% CI: -0.41 to 0.27; p = 0.67).High-flow oxygen may benefit to reduce/may be more beneficial in reducing the dyspnoea score than conventional oxygen therapy for asthma, but shows no improvement in PaCO2, PaO2, intubation or hospital length of stay.Copyright: © 2022 Termedia Sp. z o. o.

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出版当年[2022]版：

大类 | 4 区医学

小类 | 4 区皮肤病学 4 区过敏

最新[2023]版：

大类 | 4 区医学

小类 | 4 区过敏 4 区皮肤病学

第一作者：

第一作者机构： [1]Department of Gastroenterology, Suining First People's Hospital, Suining, Sichuan, China. [2]The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou, Sichuan, China.

通讯作者：

通讯机构： [4]Department of Thoracic Surgery, Suining Central Hospital, Suining, Sichuan, China. [*1]Suining Central Hospital, Suining, 629000, Sichuan, China

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